Publications by authors named "Michael A Metrick"

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Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration.
Shunsuke Koga, Michael A Metrick, Lawrence I Golbe, Alessia Santambrogio, Minji Kim, Alexandra I Soto-Beasley, Ronald L Walton, Matthew C Baker, Cristhoper Fernandez De Castro, Michael DeTure

Acta Neuropathol Commun· June 2023

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Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay.
Alessia Santambrogio, Robert I Horne, Michael A Metrick, Nicholas C T Gallagher, Z Faidon Brotzakis

J Am Chem Soc· October 2025

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Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau.
Alessia Santambrogio, Sofia Lövestam, Michael A Metrick, Thomas Löhr, Peifeng Xu

FEBS Lett· October 2025

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Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α-Synuclein at Physiological pH with Sodium Salts.
Robert I Horne, Michael A Metrick, Wing Man, Dillon J Rinauro, Z Faidon Brotzakis

ACS Chem Neurosci· September 2023

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Computational maturation of a single-domain antibody against Aβ42 aggregation.
Jiacheng Lin, Chiara Figazzolo, Michael A Metrick, Pietro Sormanni, Michele Vendruscolo

Chem Sci· October 2021

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Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear.
Natalia C Ferreira, Jorge M Charco, Jakob Plagenz, Christina D Orru, Nathanial D Denkers, Michael A Metrick

Sci Rep· April 2021

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A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases.
Michael A Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell

Acta Neuropathol Commun· February 2020

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4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration.
Eri Saijo, Michael A Metrick, Shunsuke Koga, Piero Parchi, Irene Litvan

Acta Neuropathol· January 2020

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Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration.
Eri Saijo, Michael A Metrick, Shunsuke Koga, Piero Parchi, Irene Litvan

Acta Neuropathol· January 2020

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Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons.
Michael A Metrick, Natalia do Carmo Ferreira, Eri Saijo, Andrew G Hughson, Allison Kraus

Proc Natl Acad Sci U S A· November 2019

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Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease.
Allison Kraus, Eri Saijo, Michael A Metrick, Kathy Newell, Christina J Sigurdson

Acta Neuropathol· April 2019

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Hofmeister Ion-Induced Changes in Water Structure Correlate with Changes in Solvation of an Aggregated Protein Complex.
Taylor P Light, Karen M Corbett, Michael A Metrick, Gina MacDonald

Langmuir· February 2016

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The effects of buffers and pH on the thermal stability, unfolding and substrate binding of RecA.
Michael A Metrick, Joshua E Temple, Gina MacDonald

Biophys Chem· December 2013

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