Acta Neuropathol Commun June 2023 PMID 37264457

Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration.

Shunsuke Koga, Michael A Metrick, Lawrence I Golbe, Alessia Santambrogio, Minji Kim, Alexandra I Soto-Beasley, Ronald L Walton, Matthew C Baker, Cristhoper Fernandez De Castro, Michael DeTure, David Russell, Bradford A Navia, Christine Sandiego, Owen A Ross, Michele Vendruscolo

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Mentions

Peak: 6 in Jun 2023

across 2 sources since Jun 2023

Extended reach

6,776

potential audience

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Mentions per month

Jun 2023 – Oct 2023

Where it's discussed

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YouTube1 videos

AI synopsis

What people are saying

The analysis indicates a generally positive reception, with comments like 'Fascinating case report' and 'Learn more,' demonstrating high interest and recognition of the report's importance. The tone is curious and appreciative, reflecting a moderate level of engagement that values the case's complexity without delving deeply into technical specifics.

AgreementModerate agreement

Most discussions recognize the significance of the case report, with positive comments emphasizing its importance and novelty.

InterestHigh interest

Interest is high, as posts express curiosity and enthusiasm about the complex case details and implications.

EngagementModerate engagement

Posts show moderate engagement by highlighting key findings and encouraging further exploration, but lack deep technical analysis.

ImpactModerate impact

The discussions suggest the report could influence future research or clinical understanding, though some see it as a preliminary step.

Abstract in brief

This case report discusses a patient with an unclassified tauopathy that shows features of both PSP and CBD, two distinct neurodegenerative diseases, confirmed through clinical history, neuropathology, imaging, and advanced molecular analysis.
The patient's brain exhibited mixed tau pathologies typical of PSP (like tufted astrocytes and neuronal loss in specific regions) and CBD (such as astrocytic plaques), with machine learning models and biochemical tests supporting the coexistence of these two conditions.
The findings highlight the complexity of tauopathies, suggesting that some patients may have overlapping features that require sophisticated diagnostics for accurate classification and understanding of their neurodegenerative processes.

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All mentions

Unclassified Tauopathy with Features of PSP and CBD Explained

Social RTCL TV · Oct 1, 2023 39 views

Invicro

@Invicro · X

Fascinating case report detailing a patient who had an unclassified tauopathy and features of both PSP and CBD. Learn more: https://t.co/7LGkz0S9kN https://t.co/29pXXJTJ7b

Aug 23, 2023 · 489 followers View post →

Enfermedad PSP

@enfermedadPSP · X

Jun 29, 2023 · 440 followers View post →

Arenn Carlos, MD

@ArennCarlos · X

RT @shunsuke_koga:

Jun 10, 2023 · 2 shares · 142 followers View post →

Kristophe Diaz, PhD

@KristopheDiaz · X

RT @shunsuke_koga:

Jun 10, 2023 · 2 shares · 3,495 followers View post →

Shunsuke Koga, MD, PhD

@shunsuke_koga · X

Jun 9, 2023 · 6 likes · 2 shares · 140 followers View post →

PsychiatryAI.com

@PsychiatryAIcom · X

Jun 4, 2023 · 436 followers View post →

My Neuropath News

@NeuropathClinic · X

Jun 4, 2023 · 2 likes · 1 share · 1,581 followers View post →