Publications by authors named "Michael A Repka"

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Development of 3D-printed chitosan/p-coumaric acid scaffolds for wound healing: antibacterial properties and drug release kinetics.
Nouf D Alshammari, Prateek Uttreja, Rasha Elkanayati, Leela Raghava Jaidev Chakka, Sateesh Kumar Vemula, Michael A Repka

Eur J Pharm Biopharm· February 2026

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Twin-screw melt granulation of Eudragit® FS100: optimization of coating-free delayed-release matrix tablets with HPMC K4M modulation.
Indrajeet Karnik, Prateek Uttreja, Nagarjuna Narala, Srikanth Baisa, Rasha M Elkanayati, Michael A Repka

Int J Pharm· December 2025

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Fabrication of Gastroretentive and Extended-Release Famotidine Floating Tablets via Fused Deposition Modeling.
Esraa Al Shawakri, Eman A Ashour, Rasha M Elkanayati, Mashan Almutairi, Sundus Omari, Michael A Repka

AAPS PharmSciTech· October 2025

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Investigating the Potential of Poly(2-ethyl-2-oxazoline) and Its Polymer Blends for Enhancing Fenofibrate Amorphous Solid Dispersion Dissolution Profile.
Ziru Zhang, Rasha M Elkanayati, Sheng Feng, Indrajeet Karnik, Sateesh Kumar Vemula, Michael A Repka

Pharmaceutics· September 2025

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Novel development of Poly(2-ethyl-2-oxazoline)-based mucoadhesive buccal film for poorly water-soluble drug delivery via hot-melt extrusion.
Ziru Zhang, Sheng Feng, Rasha El-Kanayati, Indrajeet Karnik, Sateesh Kumar Vemula, Michael A Repka

Eur J Pharm Biopharm· May 2025

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Kollicoat Smartseal 100P for Developing Theophylline Pellets: Exploring Taste-Masking Potential for Pediatric Applications.
Neeraja Komanduri, Mashan Almutairi, Rasha M Elkanayati, Nagireddy Dumpa, Arun Butreddy, Michael A Repka

Pharmaceutics· March 2025

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Clotrimazole mucoadhesive films with extended-release properties for vaginal candidiasis-A hot-melt extrusion application.
Kirti Sawant, Rasha M Elkanayati, Ahmed Almotairy, Michael A Repka, Mashan Almutairi

J Pharm Sci· February 2025

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Personalized Medicine Through Semisolid-Extrusion Based 3D Printing: Dual-Drug Loaded Gummies for Enhanced Patient Compliance.
Aditi Holkunde, Indrajeet Karnik, Prateek Uttreja, Nagarjuna Narala, Honghe Wang, Michael A Repka

Pharm Res· January 2025

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Self-Emulsifying Drug Delivery Systems (SEDDS): Transition from Liquid to Solid-A Comprehensive Review of Formulation, Characterization, Applications, and Future Trends.
Prateek Uttreja, Indrajeet Karnik, Ahmed Adel Ali Youssef, Nagarjuna Narala, Rasha M Elkanayati, Michael A Repka

Pharmaceutics· January 2025

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Formulation, Development, and Characterization of AMB-Based Subcutaneous Implants using PCL and PLGA via Hot-Melt Extrusion.
Kshitij Chitnis, Nagarjuna Narala, Sateesh Kumar Vemula, Sagar Narala, Sivaram Munnangi, Michael A Repka

AAPS PharmSciTech· December 2024

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Twin Screw Melt Granulation of Simvastatin: Drug Solubility and Dissolution Rate Enhancement Using Polymer Blends.
Rasha M Elkanayati, Indrajeet Karnik, Prateek Uttreja, Nagarjuna Narala, Sateesh Kumar Vemula, Michael A Repka

Pharmaceutics· December 2024

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Development of Mathematical Function Control-Based 3D Printed Tablets and Effect on Drug Release.
Honghe Wang, Indrajeet Karnik, Prateek Uttreja, Peilun Zhang, Sateesh Kumar Vemula, Michael A Repka

Pharm Res· November 2024

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Advancements in Colon-Targeted Drug Delivery: A Comprehensive Review on Recent Techniques with Emphasis on Hot-Melt Extrusion and 3D Printing Technologies.
Nouf D Alshammari, Rasha Elkanayati, Sateesh Kumar Vemula, Esraa Al Shawakri, Prateek Uttreja, Michael A Repka

AAPS PharmSciTech· October 2024

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Development and in vitro Evaluation of Cannabidiol Mucoadhesive Buccal Film Formulations Using Hot-Melt Extrusion Technology.
Iman E Taha, Mahmsoud A ElSohly, Mohamed M Radwan, Sundus Omari, Michael A Repka

Med Cannabis Cannabinoids· October 2024

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Quality by Design (QbD) Approach to Develop Colon-Specific Ketoprofen Hot-Melt Extruded Pellets: Impact of Eudragit S 100 Coating on the In Vitro Drug Release.
Sateesh Kumar Vemula, Sagar Narala, Prateek Uttreja, Nagarjuna Narala, Bhaskar Daravath, Michael A Repka

Pharmaceutics· September 2024

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Quality by design approach for fabrication of extended-release buccal films for xerostomia employing hot-melt extrusion technology.
Rasha M Elkanayati, Alaa Y Darwesh, Iman Taha, Honghe Wang, Prateek Uttreja, Michael A Repka

Eur J Pharm Biopharm· July 2024

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Formulation and evaluation of inhaled Sildenafil-loaded PLGA microparticles for treatment of pulmonary arterial hypertension (PAH): A novel high drug loaded formulation and scalable process via hot melt extrusion technology (Part Ⅰ).
Mashan Almutairi, Amr Hefnawy, Ahmed Almotairy, Ahmed Alobaida, Mohammed Alyahya, Michael A Repka

Int J Pharm· April 2024

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Development of multiple structured extended release tablets via hot melt extrusion and dual-nozzle fused deposition modeling 3D printing.
Peilun Zhang, Jinghan Li, Eman A Ashour, Sooyeon Chung, Honghe Wang, Michael A Repka

Int J Pharm· March 2024

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Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation-Where Are We Now?
Hemlata Patil, Sateesh Kumar Vemula, Sagar Narala, Preethi Lakkala, Siva Ram Munnangi, Michael A Repka

AAPS PharmSciTech· February 2024

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Formulation Development of Solid Self-Nanoemulsifying Drug Delivery Systems of Quetiapine Fumarate via Hot-Melt Extrusion Technology: Optimization Using Central Composite Design.
Prateek Uttreja, Ahmed Adel Ali Youssef, Indrajeet Karnik, Kavish Sanil, Nagarjuna Narala, Michael A Repka

Pharmaceutics· February 2024

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Development and Evaluation of Polymeric Mixed Micelles Prepared using Hot-Melt Extrusion for Extended Delivery of Poorly Water-Soluble Drugs.
Sheng Feng, Ziru Zhang, Ahmed Almotairy, Michael A Repka

J Pharm Sci· November 2023

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A Comparative Assessment of Cocrystal and Amorphous Solid Dispersion Printlets Developed by Hot Melt Extrusion Paired Fused Deposition Modeling for Dissolution Enhancement and Stability of Ibuprofen.
Preethi Mandati, Dinesh Nyavanandi, Sagar Narala, Abdullah Alzahrani, Sateesh Kumar Vemula, Michael A Repka

AAPS PharmSciTech· October 2023

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Development of Subdermal Implants Using Direct Powder Extrusion 3D Printing and Hot-Melt Extrusion Technologies.
Derick Muhindo, Eman A Ashour, Mashan Almutairi, Michael A Repka

AAPS PharmSciTech· October 2023

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Twin Screw Melt Granulation: A Single Step Approach for Developing Self-Emulsifying Drug Delivery System for Lipophilic Drugs.
Dinesh Nyavanandi, Preethi Mandati, Sagar Narala, Abdullah Alzahrani, Praveen Kolimi, Michael A Repka

Pharmaceutics· September 2023

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Investigation of hot melt extrusion process parameters on solubility and tabletability of atorvastatin calcium in presence of Neusilin US2.
Ahmed Almotairy, Mashan Almutairi, Abdulmajeed Althobaiti, Mohammed Alyahya, Sandeep Sarabu, Michael A Repka

J Drug Deliv Sci Technol· January 2023

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