Publications by authors named "Michael A Winters"

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Characterization of pneumococcal conjugates in vaccine process development by multi-detection hydrodynamic chromatography.
Xiujuan Jia, James Z Deng, Michael A Winters, Mellie June Paulines, Weidong Tong

J Pharm Biomed Anal· August 2025

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CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin.
Jackson K B Cahn, Henry Ludwicki, Jillian Shingler, Shannon Gulvin, Young Zhang, Michael A Winters

Biotechnol Bioeng· August 2025

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Automated, Quantitative Capillary Western Blots to Analyze Host Cell Proteins in COVID-19 Vaccine Produced in Vero Cell Line.
Paul F Gillespie, Yanjie Wang, Kuo Yin, Emily Groegler, Nicholas Cunningham, Michael A Winters

Vaccines (Basel)· December 2024

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Purification processes of live virus vaccine candidates expressed in adherent Vero cell lines via multimodal chromatography in flowthrough mode.
Spyridon Konstantinidis, Murphy R Poplyk, Wanli Justin Ma, Devan Reilly, Young Zhang, Michael A Winters

Biotechnol Bioeng· August 2024

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Adaptation of an rVSV Ebola vaccine purification process for rapid development of a viral vaccine candidate for SARS-CoV-2.
Laura E Kuczynski, James R Shallow, Matthew P Watson, Michael L Homsy, Thomas Svab, Michael A Winters

Biotechnol J· January 2024

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Impact of aluminum adjuvants on the stability of pneumococcal polysaccharide-protein conjugate vaccines.
William J Smith, Rachel Thompson, Patricia M Egan, Yuhua Zhang, Lani Indrawati, Michael A Winters

Vaccine· August 2023

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Protein adsorption on core-shell resins for flow-through purifications: Effect of protein molecular size, shape, and salt concentration.
Xue Mi, Sheng-Ching Wang, Michael A Winters, Giorgio Carta

Biotechnol Prog· January 2023

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Understanding the Spike Protein in COVID-19 Vaccine in Recombinant Vesicular Stomatitis Virus (rVSV) Using Automated Capillary Western Blots.
Paul F Gillespie, Yanjie Wang, Carl Hofmann, Laura E Kuczynski, Michael A Winters

ACS Omega· January 2023

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Regeneration of Capto Core 700 resin through high throughput and laboratory scale studies and impact on production of a SARS-CoV-2 vaccine candidate.
Spyridon Konstantinidis, Seth R Reinhart, Christine Castagna, Murphy R Poplyk, Richard R Rustandi, Michael A Winters

Biotechnol J· October 2022

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Functional profiling of Covid 19 vaccine candidate by flow virometry.
Ashley Prout, Richard R Rustandi, Christopher Tubbs, Michael A Winters, Philip McKenna

Vaccine· September 2022

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Analytical technology development to monitor the stability of Polysaccharide-Protein conjugate vaccines.
William J Smith, Patrick L Ahl, Bei Wang, Melissa Hamm, Richard R Rustandi, Michael A Winters

Vaccine· July 2022

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Multi-attribute characterization of pneumococcal conjugate vaccine by Size-exclusion chromatography coupled with UV-MALS-RI detections.
James Z Deng, Catherine Lancaster, Michael A Winters, Katherine M Phillips, Ping Zhuang

Vaccine· March 2022

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real time monitoring of emulsification and homogenization processes for vaccine adjuvants.
Nicole M Ralbovsky, Randal J Soukup, Justin P Lomont, Mackenzie L Lauro, Amanda Gulasarian, Michael A Winters

Analyst· January 2022

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Protein Adsorption on Core-shell Particles: Comparison of Capto™ Core 400 and 700 Resins.
Xue Mi, Preston Fuks, Sheng-Ching Wang, Michael A Winters, Giorgio Carta

J Chromatogr A· August 2021

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Immunogenicity of PCV24, an expanded pneumococcal conjugate vaccine, in adult monkeys and protection in mice.
Debra McGuinness, Robin M Kaufhold, Patrick M McHugh, Michael A Winters, William J Smith

Vaccine· July 2021

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Immunogenicity Comparison of a Next Generation Pneumococcal Conjugate Vaccine in Animal Models and Human Infants.
Jinfu Xie, Yuhua Zhang, Ivette Caro-Aguilar, Lani Indrawati, William J Smith, Michael A Winters

Pediatr Infect Dis J· January 2020

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Safety and immunogenicity of 15-valent pneumococcal conjugate vaccine (PCV15) in healthy infants.
David Greenberg, Patricia A Hoover, Timo Vesikari, Christopher Peltier, David C Hurley, Michael A Winters

Vaccine· October 2018

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Immunogenicity differences of a 15-valent pneumococcal polysaccharide conjugate vaccine (PCV15) based on vaccine dose, route of immunization and mouse strain.
Ivette Caro-Aguilar, Lani Indrawati, Robin M Kaufhold, Christine Gaunt, Yuhua Zhang, Michael A Winters

Vaccine· February 2017

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Large-scale, nonchromatographic purification of plasmid DNA.
Jason C Murphy, Michael A Winters, Sangeetha L Sagar

Methods Mol Med· October 2006

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Sterilizing filtration of plasmid DNA: effects of plasmid concentration, molecular weight, and conformation.
Matthew P Watson, Michael A Winters, Sangeetha L Sagar, John O Konz

Biotechnol Prog· June 2006

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Monitoring of RNA clearance in a novel plasmid DNA purification process.
Jason C Murphy, Michael A Winters, Matthew P Watson, John O Konz, Sangeetha L Sagar

Biotechnol Prog· January 2006

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Plasmid DNA purification by selective calcium silicate adsorption of closely related impurities.
Michael A Winters, Jesse D Richter, Sangeetha L Sagar, Ann L Lee, Russel J Lander

Biotechnol Prog· March 2004

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Fractional precipitation of plasmid DNA from lysate by CTAB.
Russel J Lander, Michael A Winters, Francis J Meacle, Barry C Buckland, Ann L Lee

Biotechnol Bioeng· September 2002

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