Publications by authors named "Michael Assfalg"

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The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells.
Angela Lauriola, Juliana Haydeé Enriqué Steinberg, Motoharu Sarubo, Elena Maspero, Fabiana Alejandra Rossi, Michael Assfalg

Mol Cell· November 2025

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SpectraSage unveils specific proteolytic patterns of 20S on mono-ubiquitylated Tau proteoforms involved in neurodegeneration.
Gabriele Antonio Zingale, Irene Pandino, Daniele Trivellato, Dario Cavaterra, Francesca Munari, Michael Assfalg

Chem Sci· September 2025

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Multiple and Alternative Sites Make Tau Protein an Adaptable Sticky Surface for the SH3 Domain of Fyn Kinase.
Roberto Tira, Giulia Leo, Laura Prandini, Carlo Giorgio Barracchia, Mariapina D'Onofrio, Michael Assfalg

Angew Chem Int Ed Engl· July 2025

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Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain.
Giovanna Viola, Daniele Trivellato, Mikko Laitaoja, Janne Jänis, Isabella C Felli, Michael Assfalg

Proc Natl Acad Sci U S A· April 2025

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Prebiotic synthesis of the major classes of iron-sulfur clusters.
Simone Scintilla, Daniele Rossetto, Martin Clémancey, Julia Rendon, Antonio Ranieri, Michael Assfalg

Chem Sci· March 2025

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Untangling the Complexity and Impact of Tau Protein Ubiquitination.
Daniele Trivellato, Francesca Munari, Michael Assfalg, Stefano Capaldi, Mariapina D'Onofrio

Chembiochem· November 2024

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Stable ubiquitin conjugation for biological interrogation of ubiquitinated tau repeat domain.
Giovanna Viola, Daniele Trivellato, Lorenzo Meulli, Roberto Tira, Angela Lauriola, Michael Assfalg

Bioorg Chem· September 2024

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Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2.
Deborah Grifagni, Elena Lenci, Alessia De Santis, Andrea Orsetti, Carlo Giorgio Barracchia, Michael Assfalg

ACS Med Chem Lett· February 2024

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Site-Specific Ubiquitination of Tau Amyloids Promoted by the E3 Ligase CHIP.
Francesca Parolini, Elham Ataie Kachoie, Giulia Leo, Laura Civiero, Luigi Bubacco, Michael Assfalg

Angew Chem Int Ed Engl· December 2023

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Ultrasmall Gold Nanoparticles as Clients of Biomolecular Condensates.
Giovanna Viola, Fulvio Floriani, Carlo Giorgio Barracchia, Francesca Munari, Mariapina D'Onofrio, Michael Assfalg

Chemistry· August 2023

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Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer's Associated Tau Protein.
Roberto Tira, Giovanna Viola, Carlo Giorgio Barracchia, Francesca Parolini, Francesca Munari, Michael Assfalg

J Agric Food Chem· August 2023

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Site-directed double monoubiquitination of the repeat domain of the amyloid-forming protein tau impairs self-assembly and coacervation.
Daniele Trivellato, Fulvio Floriani, Carlo Giorgio Barracchia, Francesca Munari, Mariapina D'Onofrio, Michael Assfalg

Bioorg Chem· March 2023

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New Paradigm for Nano-Bio Interactions: Multimolecular Assembly of a Prototypical Disordered Protein with Ultrasmall Nanoparticles.
Giovanna Viola, Carlo Giorgio Barracchia, Roberto Tira, Francesca Parolini, Giulia Leo, Michael Assfalg

Nano Lett· November 2022

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Camouflaged Fluorescent Silica Nanoparticles Target Aggregates and Condensates of the Amyloidogenic Protein Tau.
Carlo Giorgio Barracchia, Francesca Parolini, Angela Volpe, Daniele Gori, Francesca Munari, Michael Assfalg

Bioconjug Chem· July 2022

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Structural Basis for Chaperone-Independent Ubiquitination of Tau Protein by Its E3 Ligase CHIP.
Francesca Munari, Luca Mollica, Carlo Valente, Francesca Parolini, Elham Ataie Kachoie, Michael Assfalg

Angew Chem Int Ed Engl· April 2022

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Ubiquitination of Alzheimer's-related tau protein affects liquid-liquid phase separation in a site- and cofactor-dependent manner.
Francesca Parolini, Roberto Tira, Carlo Giorgio Barracchia, Francesca Munari, Stefano Capaldi, Michael Assfalg

Int J Biol Macromol· March 2022

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Inhibition of Human Monoamine Oxidases A and B by Specialized Metabolites Present in Fresh Common Fruits and Vegetables.
Claudio Marcello Marzo, Sofia Gambini, Stefania Poletti, Francesca Munari, Michael Assfalg

Plants (Basel)· January 2022

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Protein Adsorption and Conformational Changes.
Michael Assfalg

Molecules· November 2021

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Alpha-Synuclein-Nanoparticle Interactions: Understanding, Controlling and Exploiting Conformational Plasticity.
Mariapina D'Onofrio, Francesca Munari, Michael Assfalg

Molecules· November 2020

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Dynamic molecular exchange and conformational transitions of alpha-synuclein at the nano-bio interface.
Roberto Tira, Elena De Cecco, Valentina Rigamonti, Carlo Santambrogio, Carlo Giorgio Barracchia, Michael Assfalg

Int J Biol Macromol· July 2020

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A community-built calibration system: The case study of quantification of metabolites in grape juice by qNMR spectroscopy.
Biagia Musio, Rosa Ragone, Stefano Todisco, Antonino Rizzuti, Mario Latronico, Michael Assfalg

Talanta· July 2020

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Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau.
Carlo Giorgio Barracchia, Roberto Tira, Francesca Parolini, Francesca Munari, Luigi Bubacco, Michael Assfalg

Molecules· June 2020

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Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies.
Francesca Munari, Carlo Giorgio Barracchia, Francesca Parolini, Roberto Tira, Luigi Bubacco, Michael Assfalg

Int J Mol Sci· June 2020

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Semisynthetic and Enzyme-Mediated Conjugate Preparations Illuminate the Ubiquitination-Dependent Aggregation of Tau Protein.
Francesca Munari, Carlo G Barracchia, Cinzia Franchin, Francesca Parolini, Stefano Capaldi, Michael Assfalg

Angew Chem Int Ed Engl· April 2020

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Solution NMR insights into dynamic supramolecular assemblies of disordered amyloidogenic proteins.
Francesca Munari, Mariapina D'Onofrio, Michael Assfalg

Arch Biochem Biophys· April 2020

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