Publications by authors named "Michael B Battles"

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Design of orthogonal constant domain interfaces to aid proper heavy/light chain pairing of bispecific antibodies.
Kyle A Barlow, Michael B Battles, Michael E Brown, Kaleigh Canfield, Xiaojun Lu

MAbs· December 2025

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Structure-based engineering of a novel CD3ε-targeting antibody for reduced polyreactivity.
Catherine Y Liu, Cory L Ahonen, Michael E Brown, Ling Zhou, Martin Welin, Michael B Battles

MAbs· March 2023

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Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.
C Garrett Rappazzo, Longping V Tse, Chengzi I Kaku, Daniel Wrapp, Mrunal Sakharkar, Michael B Battles

Science· February 2021

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An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19.
C Garrett Rappazzo, Longping V Tse, Chengzi I Kaku, Daniel Wrapp, Mrunal Sakharkar, Michael B Battles

bioRxiv· November 2020

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Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2-imidazo[4,5-]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus.
Sandrine Vendeville, Abdellah Tahri, Lili Hu, Samuel Demin, Ludwig Cooymans, Michael B Battles

J Med Chem· August 2020

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Alternative conformations of a major antigenic site on RSV F.
Harrison G Jones, Michael B Battles, Chun-Chi Lin, Siro Bianchi, Davide Corti

PLoS Pathog· July 2019

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Respiratory syncytial virus entry and how to block it.
Michael B Battles, Jason S McLellan

Nat Rev Microbiol· April 2019

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Iterative screen optimization maximizes the efficiency of macromolecular crystallization.
Harrison G Jones, Daniel Wrapp, Morgan S A Gilman, Michael B Battles, Nianshuang Wang

Acta Crystallogr F Struct Biol Commun· February 2019

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Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein.
Michael B Battles, Vicente Más, Eduardo Olmedillas, Olga Cano, Mónica Vázquez

Nat Commun· November 2017

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Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Daiyin Tian, Michael B Battles, Syed M Moin, Man Chen, Kayvon Modjarrad

Nat Commun· November 2017

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Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.
Dirk Roymans, Sarhad S Alnajjar, Michael B Battles, Panchan Sitthicharoenchai, Polina Furmanova-Hollenstein

Nat Commun· August 2017

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NKG2D Ligand-Targeted Bispecific T-Cell Engagers Lead to Robust Antitumor Activity against Diverse Human Tumors.
Claire Godbersen, Tiffany A Coupet, Amelia M Huehls, Tong Zhang, Michael B Battles

Mol Cancer Ther· July 2017

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Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
Adriana Badarau, Harald Rouha, Stefan Malafa, Michael B Battles, Laura Walker

MAbs· October 2016

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Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Michael B Battles, Johannes P Langedijk, Polina Furmanova-Hollenstein, Supranee Chaiwatpongsakorn, Heather M Costello

Nat Chem Biol· February 2016

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Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies.
Sebastian K Grimm, Michael B Battles, Margaret E Ackerman

PLoS One· January 2016

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Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.
Harald Rouha, Adriana Badarau, Zehra C Visram, Michael B Battles, Bianka Prinz

MAbs· September 2015

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A color-based stable multi-copy integrant selection system for Pichia pastoris using the attenuated ADE1 and ADE2 genes as auxotrophic markers.
Min Du, Michael B Battles, Juergen H Nett

Bioeng Bugs· January 2012

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