Publications by authors named "Michael B Boffa"

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Evolving guidelines on lipoprotein(a).
Michael B Boffa, Marlys L Koschinsky, Robert A Hegele

Curr Opin Lipidol· December 2025

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Lipoprotein(a): An Underappreciated Inherited Risk Factor for Atherosclerosis, Aortic Stenosis, and Abdominal Aortic Aneurysm.
Marlys L Koschinsky, Dinesh K Kalra, Michael B Boffa

Annu Rev Med· November 2025

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The complex pro-atherosclerotic role of lipoprotein(a): a multiplicity of cellular targets.
Julia M Assini, Michael B Boffa, Marlys L Koschinsky

Curr Opin Lipidol· October 2025

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Lipoprotein(a) prolongs ex vivo plasma clot lysis times through effects on clot formation rate and fibrin structure.
Justin R Clark, Frances S Sutherland, Julia M Assini, Luke Daichedt, Robert Szabla, Michael B Boffa

J Thromb Haemost· October 2025

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Lp(a) as a Risk Factor for Peripheral Artery Disease: Context Is Everything.
Marlys L Koschinsky, Michael B Boffa

Arterioscler Thromb Vasc Biol· September 2025

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Variation in lipoprotein(a) response to potent lipid lowering: The role of apolipoprotein (a) isoform size.
Adedoyin Akinlonu, Michael B Boffa, Chen Lyu, Judy Zhong, Manila Jindal

J Clin Lipidol· May 2025

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Why has the "Lp(a) receptor" proven so elusive?
Gilles C Lambert, Michael B Boffa

Atherosclerosis· May 2025

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What's next for lipoprotein(a)? A National Lipid Association report from an Expert Panel Discussion.
Marlys L Koschinsky, Daniel E Soffer, Michael B Boffa

J Clin Lipidol· April 2025

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Fibrinogen and plasma clot properties are associated with apolipoprotein B and apolipoprotein B-containing lipoproteins in Africans.
Daniel Bruwer, Zelda de Lange-Loots, Marlys L Koschinsky, Michael B Boffa, Marlien Pieters

J Clin Lipidol· April 2025

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Lipoprotein(a) and cardiovascular disease.
Michael B Boffa, Marlys L Koschinsky

Biochem J· October 2024

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A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice.
Marlys L Koschinsky, Archna Bajaj, Michael B Boffa, Dave L Dixon, Keith C Ferdinand

J Clin Lipidol· June 2024

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Identification of heparin interaction sites on thrombin-activatable fibrinolysis inhibitor that modulate plasmin-mediated activation, thermal stability, and antifibrinolytic potential.
Tanya T Marar, Michael B Boffa

Res Pract Thromb Haemost· May 2024

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Optimization of plasma-based BioID identifies plasminogen as a ligand of ADAMTS13.
Hasam Madarati, Veronica DeYoung, Kanwal Singh, Taylor Sparring, Andrew C Kwong, Michael B Boffa

Sci Rep· April 2024

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High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner.
Julia M Assini, Justin R Clark, Amer Youssef, Chuce Xing, Alexandria M Doerfler, Michael B Boffa

Atherosclerosis· November 2023

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Profibrinolytic effects of rivaroxaban are mediated by thrombin-activatable fibrinolysis inhibitor and are attenuated by a naturally occurring stabilizing mutation in enzyme.
Justin J W Garabon, Michael B Boffa

J Thromb Thrombolysis· August 2023

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Lipoprotein(a) induces caspase-1 activation and IL-1 signaling in human macrophages.
Martina B Lorey, Amer Youssef, Lauri Äikäs, Matthew Borrelli, Martin Hermansson, Michael B Boffa

Front Cardiovasc Med· May 2023

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Surface LDLR is a major receptor for lipoprotein(a) clearance in male mice lacking PCSK9.
Anna Roubtsova, Corey A Scipione, Damien Garçon, Michael B Boffa, Nabil G Seidah

Biochim Biophys Acta Mol Cell Biol Lipids· April 2023

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Assays to quantify fibrinolysis: strengths and limitations. Communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee on fibrinolysis.
Ze Zheng, Liliya Mukhametova, Michael B Boffa, Ernest E Moore, Alisa S Wolberg

J Thromb Haemost· April 2023

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disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study.
Alexandria M Doerfler, So Hyun Park, Julia M Assini, Amer Youssef, Lavanya Saxena, Michael B Boffa

Mol Ther Methods Clin Dev· December 2022

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Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a).
Justin R Clark, Matthew Gemin, Amer Youssef, Santica M Marcovina, Annik Prat, Michael B Boffa

J Lipid Res· June 2022

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Understanding the ins and outs of lipoprotein (a) metabolism.
Michael B Boffa, Marlys L Koschinsky

Curr Opin Lipidol· June 2022

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Beyond fibrinolysis: The confounding role of Lp(a) in thrombosis.
Michael B Boffa

Atherosclerosis· May 2022

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Oxidized phospholipid modification of lipoprotein(a): Epidemiology, biochemistry and pathophysiology.
Marlys L Koschinsky, Michael B Boffa

Atherosclerosis· May 2022

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Apo(a) and ApoB Interact Noncovalently Within Hepatocytes: Implications for Regulation of Lp(a) Levels by Modulation of ApoB Secretion.
Amer Youssef, Justin R Clark, Santica M Marcovina, Michael B Boffa, Marlys L Koschinsky

Arterioscler Thromb Vasc Biol· March 2022

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Lipoprotein Proteomics and Aortic Valve Transcriptomics Identify Biological Pathways Linking Lipoprotein(a) Levels to Aortic Stenosis.
Raphaëlle Bourgeois, Jérôme Bourgault, Audrey-Anne Despres, Nicolas Perrot, Jakie Guertin, Michael B Boffa

Metabolites· July 2021

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