Publications by authors named "Michael B Fessler"

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Differential roles for Irgm1 in myeloid cells for immune resistance to pathogenic bacteria.
Brian E Fee, Lanette R Fee, Aemilia R Sprouse, Bruce A Vallance, Prashant Rai, Michael B Fessler

J Leukoc Biol· November 2025

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GM-CSF-dependent CD301b mouse lung dendritic cells confer tolerance to inhaled allergens.
Christina L Wilkinson, Keiko Nakano, Sara A Grimm, Gregory S Whitehead, Yukitomo Arao, Michael B Fessler

Nat Commun· September 2025

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(Inter)feron the Reaper: New Insights on an Old Cytokine in Secondary Bacterial Pneumonia.
Prashant Rai, Michael B Fessler

Am J Respir Cell Mol Biol· August 2025

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TAK1 inhibition activates pore-forming proteins to block intracellular bacterial growth through modulating mitochondria.
Wilfred López-Pérez, Roland E González-Calderón, Kazuhito Sai, Prashant Rai, Jacqueline M MacStudy, Michael B Fessler

Cell Death Dis· June 2025

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DGKα and ζ Deficiency Causes Regulatory T-Cell Dysregulation, Destabilization, and Conversion to Pathogenic T-Follicular Helper Cells to Trigger IgG1-Predominant Autoimmunity.
Lei Li, Hongxiang Huang, Hongxia Wang, Yun Pan, Huishan Tao, Michael B Fessler

bioRxiv· May 2025

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Bromine-Based Derivatization of Carboxyl-Containing Metabolites for Liquid Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry.
Kaylie I Kirkwood-Donelson, Prashant Rai, Lalith Perera, Michael B Fessler, Alan K Jarmusch

J Am Soc Mass Spectrom· April 2025

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Mechanisms and effects of activation of innate immunity by mitochondrial nucleic acids.
Prashant Rai, Michael B Fessler

Int Immunol· February 2025

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Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates.
Peer W F Karmaus, Scott M Gordon, Marcus Y Chen, Alison A Motsinger-Reif, Rodney W Snyder, Michael B Fessler

J Lipid Res· December 2024

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Flotillin-2 dampens T cell antigen sensitivity and functionality.
Sookjin Moon, Fei Zhao, Mohammad N Uddin, Charles J Tucker, Peer Wf Karmaus, Michael B Fessler

JCI Insight· December 2024

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Type I interferon signaling and peroxisomal dysfunction contribute to enhanced inflammatory cytokine production in IRGM1-deficient macrophages.
Brian E Fee, Lanette R Fee, Mark Menechella, Bethann Affeldt, Aemilia R Sprouse, Michael B Fessler

J Biol Chem· November 2024

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Production and Release of Proinflammatory Mediators by the Cockroach Allergen Bla g 1 via a Shared Membrane-Destabilization Mechanism.
Alexander C Y Foo, Matthew L Edin, Wan-Chi Lin, Fred B Lih, Scott A Gabel, Michael B Fessler

Biochemistry· July 2024

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Tissue-Resident Alveolar Macrophages Reduce Ozone-induced Inflammation via MerTK-mediated Efferocytosis.
Marissa A Guttenberg, Aaron T Vose, Anastasiya Birukova, Kaitlyn Lewars, R Ian Cumming, Michael B Fessler

Am J Respir Cell Mol Biol· June 2024

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GM-CSF-dependent CD301b+ lung dendritic cells confer tolerance to inhaled allergens.
Christina L Wilkinson, Keiko Nakano, Sara A Grimm, Gregory S Whitehead, Yukitomo Arao, Michael B Fessler

Res Sq· June 2024

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Flotillin-2 dampens T cell antigen-sensitivity and functionality.
Sookjin Moon, Fei Zhao, Mohammad N Uddin, Charles J Tucker, Peer W F Karmaus, Michael B Fessler

bioRxiv· April 2024

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Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis.
Yosuke Sakamachi, Emma Wiley, Alma Solis, Collin G Johnson, Xianglin Meng, Michael B Fessler

bioRxiv· April 2024

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Sterol biosynthesis regulates TLR signaling and the innate immune response in a Smith-Lemli-Opitz syndrome model.
Kristin Gabor, Emily V Mesev, Jennifer Madenspacher, Julie Meacham, Prashant Rai, Michael B Fessler

J Clin Invest· January 2024

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Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates.
Peer W F Karmaus, Aleksandra Tata, Julie M Meacham, Frank Day, David Thrower, Michael B Fessler

Am J Respir Cell Mol Biol· December 2023

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Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice.
Michael B Fessler, Jennifer H Madenspacher, Paul J Baker, Kerry L Hilligan, Andrea C Bohrer

Am J Respir Cell Mol Biol· December 2023

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Oxysterols in Infectious Diseases.
Cheng X Foo, Michael B Fessler, Katharina Ronacher

Adv Exp Med Biol· December 2023

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IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice.
Prashant Rai, Martin Sharpe, Charan K Ganta, Paul J Baker, Katrin D Mayer-Barber, Michael B Fessler

J Clin Invest· November 2023

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Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway.
Kenneth K Y Ting, Pei Yu, Riley Dow, Eric Floro, Hisham Ibrahim, Michael B Fessler

J Immunol· November 2023

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DNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer.
Wenling Li, Hideki Nakano, Wei Fan, Yuanyuan Li, Payel Sil, Michael B Fessler

JCI Insight· September 2023

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Race-specific association of an IRGM risk allele with cytokine expression in human subjects.
Teminioluwa Ajayi, Prashant Rai, Min Shi, Kristin A Gabor, Peer W F Karmaus, Michael B Fessler

Sci Rep· August 2023

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We need to talk about lung cancer's cholesterol-hoarding problem.
Michael B Fessler

Cell Stem Cell· June 2023

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Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma.
Eunice Y Lee, Wonson Choi, Adam B Burkholder, Lalith Perera, Jasmine A Mack, Michael B Fessler

Front Genet· June 2023

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