Publications by authors named "Michael C Gregory"

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Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1.
Yilin Liu, Yelena Grinkova, Michael C Gregory, Ilia G Denisov, James R Kincaid

Biochemistry· November 2021

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Influence of Transmembrane Helix Mutations on Cytochrome P450-Membrane Interactions and Function.
Ghulam Mustafa, Prajwal P Nandekar, Tyler J Camp, Neil J Bruce, Michael C Gregory

Biophys J· February 2019

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Human Cytochrome CYP17A1: The Structural Basis for Compromised Lyase Activity with 17-Hydroxyprogesterone.
Piotr J Mak, Ruchia Duggal, Ilia G Denisov, Michael C Gregory, Stephen G Sligar

J Am Chem Soc· June 2018

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Nanodiscs: A Controlled Bilayer Surface for the Study of Membrane Proteins.
Mark A McLean, Michael C Gregory, Stephen G Sligar

Annu Rev Biophys· May 2018

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Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202.
Michael C Gregory, Piotr J Mak, Yogan Khatri, James R Kincaid, Stephen G Sligar

Biochemistry· February 2018

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Interaction of KRas4b with anionic membranes: A special role for PIP.
Michael C Gregory, Mark A McLean, Stephen G Sligar

Biochem Biophys Res Commun· May 2017

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Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis.
Ruchia Duggal, Yilin Liu, Michael C Gregory, Ilia G Denisov, James R Kincaid

Biochem Biophys Res Commun· August 2016

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Unveiling the crucial intermediates in androgen production.
Piotr J Mak, Michael C Gregory, Ilia G Denisov, Stephen G Sligar, James R Kincaid

Proc Natl Acad Sci U S A· December 2015

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Active site proton delivery and the lyase activity of human CYP17A1.
Yogan Khatri, Michael C Gregory, Yelena V Grinkova, Ilia G Denisov, Stephen G Sligar

Biochem Biophys Res Commun· January 2014

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Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17.
Piotr J Mak, Michael C Gregory, Stephen G Sligar, James R Kincaid

Biochemistry· January 2014

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Kinetic solvent isotope effect in human P450 CYP17A1-mediated androgen formation: evidence for a reactive peroxoanion intermediate.
Michael C Gregory, Ilia G Denisov, Yelena V Grinkova, Yogan Khatri, Stephen G Sligar

J Am Chem Soc· November 2013

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