Publications by authors named "Michael C Hodder"

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Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling.
Eoghan J Mulholland, Hayley L Belnoue-Davis, Gabriel N Valbuena, Nuray Gunduz, Amelia Ligeza, Michael C Hodder

Nat Commun· June 2025

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NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Dustin J Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, Nicky J Willis, Kathryn Gilroy, Michael C Hodder

Nature· June 2021

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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.
Joshua D G Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A Ridgway, Dustin J Flanagan, Michael C Hodder

Nat Commun· June 2021

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Subversion of Niche-Signalling Pathways in Colorectal Cancer: What Makes and Breaks the Intestinal Stem Cell.
Nathalie Sphyris, Michael C Hodder, Owen J Sansom

Cancers (Basel)· February 2021

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MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice.
Marc E Healy, Yannick Boege, Michael C Hodder, Friederike Böhm, Mohsen Malehmir

Gastroenterology· July 2020

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RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes.
Joel Johansson, Mate Naszai, Michael C Hodder, Karen A Pickering, Bryan W Miller

Cell Stem Cell· April 2019

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Author Correction: Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.
David M Gay, Rachel A Ridgway, Miryam Müller, Michael C Hodder, Ann Hedley

Nat Commun· March 2019

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Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.
David M Gay, Rachel A Ridgway, Miryam Müller, Michael C Hodder, Ann Hedley

Nat Commun· February 2019

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Intestinal Stem Cell Dynamics: A Story of Mice and Humans.
Michael C Hodder, Dustin J Flanagan, Owen J Sansom

Cell Stem Cell· June 2018

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TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis.
Patrizia Cammareri, David F Vincent, Michael C Hodder, Rachel A Ridgway, Claudio Murgia

Cell Death Differ· October 2017

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HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
Kevin B Myant, Patrizia Cammareri, Michael C Hodder, Jimi Wills, Alex Von Kriegsheim

EMBO Mol Med· February 2017

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