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Publications by authors named "Michael C Linhares"

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A novel series of non-carboxylic acid, non-hydantoin inhibitors of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and congeners.
Banavara L Mylari, Sandra J Armento, David A Beebe, Edward L Conn, James B Coutcher, Michael C Linhares

J Med Chem· October 2005


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A highly selective, non-hydantoin, non-carboxylic acid inhibitor of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran- 2-sulfonyl)-2-H-pyridazin-3-one.
Banavara L Mylari, Sandra J Armento, David A Beebe, Edward L Conn, James B Coutcher, Michael C Linhares

J Med Chem· June 2003


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A sorbitol dehydrogenase inhibitor of exceptional in vivo potency with a long duration of action: 1-(R)-[4-[4-(4,6-dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl]ethanol.
Banavara L Mylari, Peter J Oates, William J Zembrowski, David A Beebe, Edward L Conn, Michael C Linhares

J Med Chem· September 2002


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