Publications by authors named "Michael C Quirk"

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Changes in 24(S)-Hydroxycholesterol Are Associated with Cognitive Performance in Early Huntington's Disease: Data from the TRACK and ENROLL HD Cohorts.
Sarah M Gray, Jing Dai, Anne C Smith, Jacob T Beckley, Negah Rahmati, Michael C Quirk

J Huntingtons Dis· November 2024

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Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors.
Jacob T Beckley, Teresa K Aman, Michael A Ackley, Tatiana M Kazdoba, Michael C Lewis, Michael C Quirk

Br J Pharmacol· April 2024

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Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions.
Weiting Tang, Jacob T Beckley, Jin Zhang, Rui Song, Yuchen Xu, Michael C Quirk

Cell Mol Life Sci· January 2023

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SAGE-718: A First-in-Class -Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment.
Matthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, Zhu Bai, Jacob T Beckley, Michael C Quirk

J Med Chem· July 2022

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Allopregnanolone Mediates Affective Switching Through Modulation of Oscillatory States in the Basolateral Amygdala.
Pantelis Antonoudiou, Phillip L W Colmers, Najah L Walton, Grant L Weiss, Anne C Smith, Michael C Quirk

Biol Psychiatry· February 2022

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Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA receptor positive allosteric modulator.
Alison L Althaus, Michael A Ackley, Gabriel M Belfort, Steven M Gee, Jing Dai, Michael C Quirk

Neuropharmacology· December 2020

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Neuroactive Steroid -Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity.
Daniel S La, Francesco G Salituro, Gabriel Martinez Botella, Andrew M Griffin, Zhu Bai, Michael C Quirk

J Med Chem· August 2019

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Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study.
Gerard Sanacora, Michael R Johnson, Arif Khan, Sarah D Atkinson, Robert R Riesenberg, Michael C Quirk

Neuropsychopharmacology· March 2017

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EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA(Aα2/3)-positive allosteric modulators at nonsedating anxiolytic doses.
Edward P Christian, Dean H Snyder, Wei Song, David A Gurley, Joanne Smolka, Michael C Quirk

J Neurophysiol· January 2015

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A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration.
Michael C Quirk, Dara L Sosulski, Claudia E Feierstein, Naoshige Uchida, Zachary F Mainen

Front Syst Neurosci· July 2011

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Stimulus-specific adaptation in auditory cortex is an NMDA-independent process distinct from the sensory novelty encoded by the mismatch negativity.
Brandon J Farley, Michael C Quirk, James J Doherty, Edward P Christian

J Neurosci· December 2010

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A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.
Jana K Shirey, Ashley E Brady, Paulianda J Jones, Albert A Davis, Thomas M Bridges, Michael C Quirk

J Neurosci· November 2009

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Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.
Simon Sydserff, E J Sutton, Dekun Song, Michael C Quirk, Carla Maciag

Biochem Pharmacol· October 2009

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Representation of spatial goals in rat orbitofrontal cortex.
Claudia E Feierstein, Michael C Quirk, Naoshige Uchida, Dara L Sosulski, Zachary F Mainen

Neuron· August 2006

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Dynamic analyses of information encoding in neural ensembles.
Riccardo Barbieri, Loren M Frank, David P Nguyen, Michael C Quirk, Victor Solo

Neural Comput· February 2004

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Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience.
Kazu Nakazawa, Linus D Sun, Michael C Quirk, Laure Rondi-Reig, Matthew A Wilson

Neuron· April 2003

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Requirement for hippocampal CA3 NMDA receptors in associative memory recall.
Kazu Nakazawa, Michael C Quirk, Raymond A Chitwood, Masahiko Watanabe, Mark F Yeckel

Science· July 2002

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