Publications by authors named "Michael D Cameron"

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Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex.
Linjie Yuan, Wenzhi Ji, Brendan G Dwyer, Joey Lu, Jing Bian, Michael D Cameron

Cancer Discov· December 2025

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A triple-action PROTAC for wild-type p53 cancer therapy.
Gregory H Bird, Utsarga Adhikary, Michael J Schmidt, Marina Godes, Bethany Tesar, Michael D Cameron

Cell Rep Med· December 2025

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Combining spironolactone to antiretroviral therapy accelerates HIV decay in humanized mice.
Lijun Ling, Luisa P Mori, Andrew Soper, Wenbo Yao, Andrew T McAuley, Michael D Cameron

Emerg Microbes Infect· December 2025

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GTP release-selective agonists prolong opioid analgesic efficacy.
Edward L Stahl, Matthew A Swanson, Vuong Q Dang, Michael D Cameron, Nicole M Kennedy

Nature· December 2025

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Structural determinants of non-covalent PPARγ inverse agonism and their therapeutic implications.
Kuang-Ting Kuo, Bilel Bdiri, Yuanjun He, Ruben D Garcia-Ordonez, Daniel P McDougal, Michael D Cameron

Nat Commun· December 2025

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Exogenous estrogen enhances T cell activation in male primates.
Patricia A Hahn, Joan Escrivà-Font, Eric S Alexander, Kimberly Weisgrau, Tianling Ou, Michael D Cameron

Cell Rep· September 2025

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Development of a Novel Compound Effective Against Juvenile, Adult, and Drug-Resistant Species.
Sevan N Alwan, Alexander B Taylor, Stanton F McHardy, Michael D Cameron, Philip T LoVerde

Pharmaceutics· September 2025

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MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastoma.
Rajappa S Kenchappa, Laszlo Radnai, Erica J Young, Natanael Zarco, Li Lin, Michael D Cameron

Cell· August 2025

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Development of clinically viable non-muscle myosin II small molecule inhibitors.
Laszlo Radnai, Erica J Young, Carlos Kikuti, Katalin Toth, Minghai Zhou, Michael D Cameron

Cell· August 2025

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Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau's Pre-mRNA Splicing.
Peiyuan Zhang, Amirhossein Taghavi, Masahito Abe, Haruo Aikawa, Yoshihiro Akahori, Michael D Cameron

ACS Chem Biol· July 2025

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Zika virus-induced fetal demise is triggered by strain- and dose-specific RLR-driven activation of the interferon response in the decidua, placenta, and fetus in mice.
Ellie K Bohm, David Castañeda, Qun Lu, Michael D Cameron, Matthew T Aliota

J Virol· June 2025

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Linker Optimization Enhances the Potency of Ribonuclease-Targeting Chimeras in Cancer Models.
Samantha M Meyer, Sandra Kovachka, Tenghui Wang, Michael D Cameron, Jessica L Childs-Disney

J Med Chem· June 2025

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A cryptic pocket in CB1 drives peripheral and functional selectivity.
Vipin Ashok Rangari, Evan S O'Brien, Alexander S Powers, Richard A Slivicki, Zachariah Bertels, Michael D Cameron

Nature· April 2025

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Zika virus-induced fetal demise is driven by strain- and dose-specific RLR-driven activation of the interferon response in the decidua, placenta, and fetus in mice.
Ellie K Bohm, David Castañeda, Qun Lu, Michael D Cameron, Matthew T Aliota

bioRxiv· February 2025

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Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic-like behaviors in mice.
Allison Volf, Tarsis F Brust, Robin R Kobylski, Kerri M Czekner, Edward L Stahl, Michael D Cameron

bioRxiv· February 2025

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Synthesis and evaluation of 3,4,5-trisubstituted triazoles as G protein-biased kappa opioid receptor agonists.
Ashley E Trojniak, Vuong Q Dang, Kerri M Czekner, Robin J Russo, Lilyan M Mather, Michael D Cameron

Eur J Med Chem· October 2024

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Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential.
Laszlo Radnai, Erica J Young, Carlos Kikuti, Madalyn Hafenbreidel, Rebecca F Stremel, Michael D Cameron

bioRxiv· October 2024

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SR9883 is a novel small-molecule enhancer of α4β2* nicotinic acetylcholine receptor signaling that decreases intravenous nicotine self-administration in rats.
Kevin M Braunscheidel, George Voren, Christie D Fowler, Qun Lu, Alexander Kuryatov, Michael D Cameron

Front Mol Neurosci· September 2024

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MT-125 Inhibits Non-Muscle Myosin IIA and IIB, Synergizes with Oncogenic Kinase Inhibitors, and Prolongs Survival in Glioblastoma.
Rajappa Kenchappa, Laszlo Radnai, Erica J Young, Natanael Zarco, Li Lin, Michael D Cameron

bioRxiv· April 2024

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HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents.
Karoline B Waitman, Larissa C de Almeida, Marina C Primi, Jorge A E G Carlos, Claudia Ruiz, Michael D Cameron

Eur J Med Chem· January 2024

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Basolateral amygdala corticotropin releasing factor receptor 2 interacts with nonmuscle myosin II to destabilize memory in males.
Madalyn Hafenbreidel, Surya Pandey, Sherri B Briggs, Meghana Arza, Shalakha Bonthu, Michael D Cameron

Neurobiol Learn Mem· December 2023

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Structure-Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 () for Autoimmune Disorders.
Yuanjun He, Di Zhu, Kevin Greenman, Claudia Ruiz, Jinsai Shang, Michael D Cameron

J Med Chem· November 2023

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1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors.
Maurício T Tavares, Arne Krüger, Sun L Rei Yan, Karoline B Waitman, Vinícius M Gomes, Michael D Cameron

Sci Rep· November 2023

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Probing a distinct druggable tubulin binding site with gatorbulins 1-7, their metabolic and physicochemical properties, and pharmacological consequences.
Qi-Yin Chen, Ranjala Ratnayake, Rafael Hortigüela, Gustavo M Seabra, Michael D Cameron

Bioorg Med Chem· October 2023

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Basolateral Amygdala Corticotrophin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory.
Madalyn Hafenbreidel, Sherri B Briggs, Meghana Arza, Shalakha Bonthu, Cadence Fisher, Michael D Cameron

bioRxiv· May 2023

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