Publications by authors named "Michael D Edstein"

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Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with .
Rebecca Webster, Damian A Oyong, Stacey Llewellyn, Azrin N Abd-Rahman, Adam J Potter, Michael D Edstein

Sci Transl Med· November 2025

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Therapeutic efficacy monitoring of pyronaridine-artesunate (Pyramax®) in treating uncomplicated Plasmodium falciparum malaria in Gia Lai province, Vietnam from 2022 to 2023.
Nguyen Van Thanh, Huynh Hong Quang, Nguyen Ngoc San, Nguyen Kien Cuong, Nguyen Thi Minh Trinh, Michael D Edstein

J Antimicrob Chemother· October 2025

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Exploring the Utility of Cell-Penetrating Peptides as Vehicles for the Delivery of Distinct Antimalarial Drug Cargoes.
Caitlin L Gare, Isabella R Palombi, Andrew M White, Marina Chavchich, Michael D Edstein

ChemMedChem· January 2025

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Therapeutic efficacy of pyronaridine-artesunate (Pyramax) in treating malaria in the central highlands of Vietnam.
Nguyen Duc Manh, Nguyen Van Thanh, Huynh Hong Quang, Nguyen Thi Thanh Van, Nguyen Ngoc San, Michael D Edstein

Antimicrob Agents Chemother· September 2024

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Cross-sectional survey of asymptomatic malaria in Dak Nong province in the Central Highlands of Vietnam for the malaria elimination roadmap.
Huynh Hong Quang, Marina Chavchich, Nguyen Thi Minh Trinh, Nguyen Duc Manh, Michael D Edstein

PLoS One· July 2024

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Rapid and non-invasive detection of malaria parasites using near-infrared spectroscopy and machine learning.
Maggy T Sikulu-Lord, Michael D Edstein, Brendon Goh, Anton R Lord, Jye A Travis

PLoS One· March 2024

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Cytochrome P450 2D6 profiles and anti-relapse efficacy of tafenoquine against in Australian Defence Force personnel.
Simone Dowd, Nanhua Chen, Michelle L Gatton, Michael D Edstein, Qin Cheng

Antimicrob Agents Chemother· December 2023

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Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum.
Bridget E Barber, Azrin N Abd-Rahman, Rebecca Webster, Adam J Potter, Stacey Llewellyn, Michael D Edstein

Clin Infect Dis· June 2023

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Transmission Blocking Activity of Low-dose Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum.
Rebecca Webster, Hayley Mitchell, Jenny M Peters, Juanita Heunis, Brighid O'Neill, Michael D Edstein

Clin Infect Dis· February 2023

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Quantification of Tafenoquine and 5,6-Orthoquinone Tafenoquine by UHPLC-MS/MS in Blood, Plasma, and Urine, and Application to a Pharmacokinetic Study.
Geoffrey W Birrell, Karin Van Breda, Bridget Barber, Rebecca Webster, James S McCarthy, Michael D Edstein

Molecules· November 2022

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The Effect of Regularly Dosed Acetaminophen vs No Acetaminophen on Renal Function in Plasmodium knowlesi Malaria (PACKNOW): A Randomized, Controlled Trial.
Daniel J Cooper, Matthew J Grigg, Katherine Plewes, Giri S Rajahram, Kim A Piera, Michael D Edstein

Clin Infect Dis· October 2022

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Cross-sectional study of asymptomatic malaria and seroepidemiological surveillance of seven districts in Gia Lai province, Vietnam.
Nguyen Ngoc San, Nguyen Xuan Kien, Nguyen Duc Manh, Nguyen Van Thanh, Marina Chavchich, Michael D Edstein

Malar J· February 2022

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Pyronaridine-Artesunate (Pyramax) for Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of Vietnam.
Nguyen Duc Manh, Nguyen Van Thanh, Huynh Hong Quang, Nguyen Thi Thanh Van, Nguyen Ngoc San, Michael D Edstein

Antimicrob Agents Chemother· November 2021

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The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Katherine M Ellis, Leonardo Lucantoni, Marina Chavchich, Matthew Abraham, Amanda De Paoli, Michael D Edstein

Antimicrob Agents Chemother· October 2021

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Entomological survey in two communes with residual malaria transmission in Gia Lai Province in the central highlands of Vietnam.
Thai Quang Nguyen, Manh Duc Nguyen, Vinh Xuan Pham, Huan Mah Ro, Michael D Edstein

Malar J· October 2021

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Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity.
Jan Frydrych, Dianne T Keough, Marina Chavchich, Jye Travis, Martin Dračínský, Michael D Edstein

Eur J Med Chem· July 2021

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Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines.
Daniel L Priebbenow, Mitch Mathiew, Da-Hua Shi, Jitendra R Harjani, Julia G Beveridge, Michael D Edstein

J Med Chem· April 2021

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The application of spectroscopy techniques for diagnosis of malaria parasites and arboviruses and surveillance of mosquito vectors: A systematic review and critical appraisal of evidence.
Brendon Goh, Koek Ching, Ricardo J Soares Magalhães, Silvia Ciocchetta, Michael D Edstein

PLoS Negl Trop Dis· April 2021

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Multidrug-Resistant Plasmodium falciparum Parasites in the Central Highlands of Vietnam Jeopardize Malaria Control and Elimination Strategies.
Huynh Hong Quang, Marina Chavchich, Nguyen Thi Minh Trinh, Kimberly A Edgel, Michael D Edstein

Antimicrob Agents Chemother· March 2021

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The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network.
Mohammad S Hossain, Robert J Commons, Nicholas M Douglas, Kamala Thriemer, Bereket H Alemayehu, Michael D Edstein

PLoS Med· November 2020

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Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against .
Geoffrey W Birrell, Matthew P Challis, Amanda De Paoli, Dovile Anderson, Shane M Devine, Michael D Edstein

Mol Cell Proteomics· February 2020

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Efficacy and Pharmacokinetics of the 2-Aminomethylphenol Antimalarial JPC-3210 in the Monkey-Human Malaria Model.
Fiona J McCallum, Geoffrey W Birrell, Marina Chavchich, Ivor Harris, Nicanor Obaldia, Michael D Edstein

Antimicrob Agents Chemother· February 2020

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Pharmacokinetics and Antimalarial Activity of Artesunate-Amodiaquine plus Methylene Blue in Healthy Volunteers.
Chu Xuan Anh, Marina Chavchich, Geoffrey W Birrell, Karin Van Breda, Thomas Travers, Michael D Edstein

Antimicrob Agents Chemother· February 2020

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Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation.
Tomáš Klejch, Dianne T Keough, Marina Chavchich, Jye Travis, Jan Skácel, Michael D Edstein

Eur J Med Chem· December 2019

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Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration.
Christopher J Parkinson, Geoffrey W Birrell, Marina Chavchich, Donna Mackenzie, Richard K Haynes, Michael D Edstein

J Antimicrob Chemother· October 2019

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