Publications by authors named "Michael D Stone"

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RNA structure analyzed by chemical probing and mutational profiling with sequencing (MaPseq).
Eva Edelson, Nicholas M Forino, Michael D Stone

Methods Enzymol· December 2025

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Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex.
Samantha L Sanford, Mareike Badstübner, Michael Gerber, William Mannherz, Noah Lampl, Michael D Stone

Nat Commun· December 2025

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OpenASO: RNA Rescue-designing splice-modulating antisense oligonucleotides through community science.
Victor Tse, Martin Guiterrez, Jill Townley, Jonathan Romano, Jennifer Pearl, Michael D Stone

RNA· July 2025

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Chemotherapeutic 6-thio-2'-deoxyguanosine selectively targets and inhibits telomerase by inducing a non-productive telomere-bound telomerase complex.
Samantha L Sanford, Mareike Badstübner, Michael Gerber, William Mannherz, Noah Lampl, Michael D Stone

bioRxiv· June 2025

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A novel splice site variant in leads to aberrant splicing and loss of DEGS1 enzyme activity, a VUS resolved.
Holly C Beale, Victor Tse, Joanna Y Lee, Jon Akutagawa, Yusuph Mavura, Michael D Stone

medRxiv· April 2025

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Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq.
Nicholas M Forino, Jia Zheng Woo, Arthur J Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Michael D Stone

Nat Commun· January 2025

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OpenASO: RNA Rescue - designing splice-modulating antisense oligonucleotides through community science.
Victor Tse, Martin Guiterrez, Jill Townley, Jonathan Romano, Jennifer Pearl, Michael D Stone

bioRxiv· October 2024

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Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq.
Nicholas M Forino, Jia Zheng Woo, Arthur J Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Michael D Stone

bioRxiv· August 2024

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An intronic RNA element modulates Factor VIII exon-16 splicing.
Victor Tse, Guillermo Chacaltana, Martin Gutierrez, Nicholas M Forino, Arcelia G Jimenez, Michael D Stone

Nucleic Acids Res· January 2024

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Real-time detection of human telomerase DNA synthesis by multiplexed single-molecule FRET.
Jendrik Hentschel, Mareike Badstübner, Junhong Choi, Clive R Bagshaw, Christopher P Lapointe, Michael D Stone

Biophys J· September 2023

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Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism.
Neelam Hassan, Celia L Gregson, Haotian Tang, Marc van der Kamp, Paul Leo, Michael D Stone

J Bone Miner Res· May 2023

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Rescue of blood coagulation Factor VIII exon-16 mis-splicing by antisense oligonucleotides.
Victor Tse, Guillermo Chacaltana, Martin Gutierrez, Nicholas M Forino, Arcelia G Jimenez, Michael D Stone

bioRxiv· April 2023

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RNA:RNA interaction in ternary complexes resolved by chemical probing.
Elnaz Banijamali, Lorenzo Baronti, Walter Becker, Joanna J Sajkowska-Kozielewicz, Ting Huang, Michael D Stone

RNA· March 2023

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Single-Molecule Mechanical Analysis of Strand Invasion in Human Telomere DNA.
Terren R Chang, Xi Long, Shankar Shastry, Joseph W Parks, Michael D Stone

Biochemistry· August 2022

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A method for campus-wide SARS-CoV-2 surveillance at a large public university.
Terren Chang, Jolene M Draper, Anouk Van den Bout, Ellen Kephart, Hannah Maul-Newby, Michael D Stone

PLoS One· January 2022

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The Processivity of Telomerase: Insights from Kinetic Simulations and Analyses.
Clive R Bagshaw, Jendrik Hentschel, Michael D Stone

Molecules· December 2021

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Cryo-EM structures tell a tale of two telomerases.
Nicholas M Forino, Jendrik Hentschel, Michael D Stone

Nat Struct Mol Biol· June 2021

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Folding heterogeneity in the essential human telomerase RNA three-way junction.
Christina Palka, Nicholas M Forino, Jendrik Hentschel, Rhiju Das, Michael D Stone

RNA· December 2020

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Clinical Guidelines on Paget's Disease of Bone.
Stuart H Ralston, Luis Corral-Gudino, Cyrus Cooper, Roger M Francis, William D Fraser, Michael D Stone

J Bone Miner Res· December 2019

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Single-Molecule Analysis of Reverse Transcriptase Enzymes.
Linnea I Jansson, Michael D Stone

Cold Spring Harb Perspect Biol· September 2019

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Oestrogen-deficiency induces bone loss by modulating CD14 monocyte and CD4 T cell DR3 expression and serum TL1A levels.
Fraser L Collins, Michael D Stone, Jane Turton, Laura R McCabe, Eddie C Y Wang

BMC Musculoskelet Disord· July 2019

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Telomere DNA G-quadruplex folding within actively extending human telomerase.
Linnea I Jansson, Jendrik Hentschel, Joseph W Parks, Terren R Chang, Cheng Lu, Michael D Stone

Proc Natl Acad Sci U S A· May 2019

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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline.
Stuart H Ralston, Luis Corral-Gudino, Cyrus Cooper, Roger M Francis, William D Fraser, Michael D Stone

J Bone Miner Res· April 2019

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Detailed view of human telomerase enzyme invites rethink of its structure.
Michael D Stone

Nature· May 2018

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Direct observation of nucleic acid binding dynamics by the telomerase essential N-terminal domain.
Shankar Shastry, Olga Steinberg-Neifach, Neal Lue, Michael D Stone

Nucleic Acids Res· April 2018

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