Publications by authors named "Michael D Wyatt"

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AI-based mining of biomedical literature: Applications for drug repurposing for the treatment of dementia.
Aliaksandra Sikirzhytskaya, Ilya Tyagin, S Scott Sutton, Michael D Wyatt, Ilya Safro

Artif Intell Med· October 2025

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Structural regulation of PLK1 activity: implications for cell cycle function and drug discovery.
Danda Chapagai, Klaus Strebhardt, Michael D Wyatt, Campbell McInnes

Cancer Gene Ther· June 2025

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Schizophrenia, Off-Label Antipsychotics, and Dementia Risk in People With HIV.
Joseph Magagnoli, Tammy H Cummings, Michael D Wyatt, Michael Shtutman, S Scott Sutton

J Acquir Immune Defic Syndr· February 2025

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Semi-Synthesis of Dimeric Cannabidiol Derivatives and Evaluation of their Affinity at Neurological Targets.
Zachary Stryker, Jorge I Castillo-Arellano, Stephen J Cutler, Michael D Wyatt, Francisco León

J Nat Prod· February 2025

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The impact of diet-induced obesity on 5 fluorouracil-induced tumor and liver immune cell cytotoxicity.
Brandon N VanderVeen, Thomas D Cardaci, Brooke M Bullard, Christian A Unger, Jeffrey C Freeman, Michael D Wyatt

Am J Physiol Cell Physiol· January 2025

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Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among people with HIV.
Tammy H Cummings, Joseph Magagnoli, Aliaksandra Sikirzhytskaya, Ilya Tyagin, Ilya Safro, Michael D Wyatt

AIDS· December 2024

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Suppression of HIV-TAT and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters.
B Celia Cui, Marina Aksenova, Aliaksandra Sikirzhytskaya, Diana Odhiambo, Elizaveta Korunova, Michael D Wyatt

J Neurovirol· August 2024

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AI-based mining of biomedical literature: Applications for drug repurposing for the treatment of dementia.
Aliaksandra Sikirzhytskaya, Ilya Tyagin, S Scott Sutton, Michael D Wyatt, Ilya Safro

Res Sq· August 2024

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AI-based mining of biomedical literature: Applications for drug repurposing for the treatment of dementia.
Aliaksandra Sikirzhytskaya, Ilya Tyagin, S Scott Sutton, Michael D Wyatt, Ilya Safro

bioRxiv· June 2024

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Synthesis and Monoamine Oxidase Inhibitory Activity of Halogenated Flavones.
Jorge I Castillo-Arellano, Zachary Stryker, Michael D Wyatt, Francisco León

ACS Med Chem Lett· May 2024

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Collateral damage of NUDT15 deficiency in cancer provides a cancer pharmacogenetic therapeutic window with thiopurines.
Jacob C Massey, Joseph Magagnoli, S Scott Sutton, Phillip J Buckhaults, Michael D Wyatt

bioRxiv· April 2024

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Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among patients with human immunodeficiency virus.
Tammy H Cummings, Joseph Magagnoli, Aliaksandra Sikirzhytskaya, Ilya Tyagin, Ilya Safro, Michael D Wyatt

medRxiv· January 2024

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Suppression of HIV and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters.
B Celia Cui, Marina Aksenova, Aliaksandra Sikirzhytskaya, Diana Odhiambo, Elizaveta Korunova, Michael D Wyatt

bioRxiv· September 2023

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Structural Basis for Variations in Polo-like Kinase 1 Conformation and Intracellular Stability Induced by ATP-Competitive and Novel Noncompetitive Abbapolin Inhibitors.
Danda Chapagai, George Merhej, Campbell McInnes, Michael D Wyatt

ACS Chem Biol· July 2023

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Inhibitors of the PLK1 polo-box domain: drug design strategies and therapeutic opportunities in cancer.
Jessy M Stafford, Michael D Wyatt, Campbell McInnes

Expert Opin Drug Discov· January 2023

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Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.
Megha Jhanji, Chintada Nageswara Rao, Jacob C Massey, Marion C Hope, Xueyan Zhou, Michael D Wyatt

Nat Commun· June 2022

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Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE.
Sandra N Craig, Merissa Baxter, Danda Chapagai, Jessy M Stafford, Elmar Nurmemmedov, Michael D Wyatt

Eur J Med Chem· January 2022

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Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells.
Danda Chapagai, Gurusankar Ramamoorthy, Jessy Varghese, Elmar Nurmemmedov, Campbell McInnes, Michael D Wyatt

J Med Chem· July 2021

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Corrigendum to "The soluble nectin-4 ecto-domain promotes breast cancer induced angiogenesis via endothelial Integrin-β4" [Int J Biochem Cell Biol, 2018, Sep, 102, 151-160].
Sumit Siddharth, Anmada Nayak, Sarita Das, Deepika Nayak, Jyochanamayi Panda, Michael D Wyatt

Int J Biochem Cell Biol· January 2021

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Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly.
B Celia Cui, Vitali Sikirzhytski, Marina Aksenova, Matthew D Lucius, Gabrielle H Levon, Michael D Wyatt

Biochem Pharmacol· December 2020

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Improving oncology biosimilar launches in the EU, the USA, and Japan: an updated Policy Review from the Southern Network on Adverse Reactions.
Charles L Bennett, Martin W Schoen, Shamia Hoque, Bartlett J Witherspoon, David M Aboulafia, Michael D Wyatt

Lancet Oncol· December 2020

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Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation.
Marina Aksenova, Justin Sybrandt, Biyun Cui, Vitali Sikirzhytski, Hao Ji, Michael D Wyatt

J Neuroimmune Pharmacol· June 2020

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Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor.
Merissa Baxter, Danda Chapagai, Sandra Craig, Cecilia Hurtado, Jessy Varghese, Michael D Wyatt

ChemMedChem· June 2020

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Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice.
Anusha Chaparala, Deepak Poudyal, Hossam Tashkandi, Erin E Witalison, Alexander A Chumanevich, Michael D Wyatt

Oncotarget· June 2020

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Microbes as Drugs: The Potential of Pharmabiotics.
Chloé E LeBegue, Bryan L Love, Michael D Wyatt

Pharmacotherapy· February 2020

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