Publications by authors named "Michael Devito"

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Collaborative evaluation of in silico predictions for high throughput toxicokinetics.
John F Wambaugh, Nisha S Sipes, Gilberto Padilla Mercado, Jon A Arnot, Linda Bertato, Michael J Devito

Toxicol In Vitro· January 2026

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An in vitro-in silico workflow for predicting renal clearance of environmental chemicals and drugs.
Courtney Sakolish, Hsing-Chieh Lin, Haley L Moyer, Lucie C Ford, Charles H Christen, Michael J DeVito

Toxicology· January 2026

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Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs).
Grace Patlewicz, Richard Judson, Katie Paul Friedman, Barbara A Wetmore, Michael J DeVito

J Toxicol Environ Health B Crit Rev· December 2025

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Transcriptomic dose response assessment of PFAS chemicals 3:3 fluorotelomer carboxylic acid, 7:3 fluorotelomer alcohol, and perfluorohexanesulfonamide.
Esra Mutlu, Leah Wehmas, Alison H Harrill, Michael Devito, Russell S Thomas

Toxicology· November 2025

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Database-calibrated toxicity values for human health assessment based on existing toxicology data for one thousand chemicals.
Alison H Harrill, Shintaro Hagiwara, Chelsea A Weitekamp, Paul C Stanish, Jonathan T Wall, Michael J Devito

J Toxicol Environ Health B Crit Rev· September 2025

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Applying New Approach Methods for Toxicokinetics for Chemical Risk Assessment.
John F Wambaugh, Katie Paul Friedman, Marc A Beal, Ivy Moffat, Michael F Hughes, Michael DeVito

Chem Res Toxicol· August 2025

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Immunotoxicity of Four Per- and Polyfluoroalkyl Substances Following 28-Day Oral Repeat Dosing in Rats Assessed by the Anti-Sheep Red Blood Cell IgM Response.
Michael F Hughes, Michael J DeVito, Grace Patlewicz, Russell S Thomas, Linda D Adams

Toxics· June 2025

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Non-Targeted Analysis (NTA) of Plasma and Liver from Sprague Dawley Rats Exposed to Perfluorohexanesulfonamide (PFHxSA), a Precursor to Perfluorohexane Sulfonic Acid (PFHxS).
Denise K MacMillan, Jackson G Bounds, William A Willis, Mark J Strynar, Barbara A Wetmore, Michael J Devito

Toxics· June 2025

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Subchronic Toxicities of Four Per- and Polyfluoroalkyl Substances (PFASs) by Oral Exposure in Sprague-Dawley Rats.
Elaina M Kenyon, Michael J Devito, Grace Patlewicz, Linda D Adams, Russell S Thomas

Toxics· June 2025

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Lessons learned from evaluating defined chemical mixtures in a high-throughput estrogen receptor assay system.
Fred Parham, Kristin M Eccles, Cynthia V Rider, Srilatha Sakamuru, Menghang Xia, Michael J DeVito

Toxicol Sci· May 2025

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Enabling transparent toxicokinetic modeling for public health risk assessment.
Sarah E Davidson-Fritz, Caroline L Ring, Marina V Evans, Celia M Schacht, Xiaoqing Chang, Michael J Devito

PLoS One· April 2025

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A physiologically based pharmacokinetic (PBPK) model describing the kinetics of a commercial mixture α-, β-, and γ-hexabromocyclododecane exposure in mice.
Claude Emond, Michael J DeVito, Linda S Birnbaum

Arch Toxicol· March 2025

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A new approach methodology to identify tumorigenic chemicals using short-term exposures and transcript profiling.
Victoria Ledbetter, Scott Auerbach, Logan J Everett, Beena Vallanat, Anna Lowit, Michael Devito

Front Toxicol· October 2024

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In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories.
David M Crizer, Julie R Rice, Marci G Smeltz, Katelyn S Lavrich, Krishna Ravindra, Michael DeVito

Toxics· September 2024

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A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS).
Richard S Judson, Doris Smith, Michael DeVito, John F Wambaugh, Barbara A Wetmore

Toxics· April 2024

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The 2022 world health organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls.
Michael DeVito, Bas Bokkers, Majorie B M van Duursen, Karin van Ede, Mark Feeley

Regul Toxicol Pharmacol· January 2024

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Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment.
Daniele Wikoff, Caroline Ring, Michael DeVito, Nigel Walker, Linda Birnbaum

Regul Toxicol Pharmacol· December 2023

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Dose Response, Dosimetric, and Metabolic Evaluations of Replacement PFAS Perfluoro-(2,5,8-trimethyl-3,6,9-trioxadodecanoic) Acid (HFPO-TeA).
Aero Renyer, Krishna Ravindra, Barbara A Wetmore, Jermaine L Ford, Michael DeVito

Toxics· November 2023

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A multi-tiered hierarchical Bayesian approach to derive toxic equivalency factors for dioxin-like compounds.
Caroline Ring, Alexander Blanchette, William D Klaren, Seneca Fitch, Laurie Haws, Michael DeVito

Regul Toxicol Pharmacol· September 2023

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Determinants of gene expression in the human liver: Impact of aging and sex on xenobiotic metabolism.
J Christopher Corton, Janice S Lee, Jie Liu, Hongzu Ren, Beena Vallanat, Michael DeVito

Exp Gerontol· November 2022

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A PBPK model describing the pharmacokinetics of γ-HBCD exposure in mice.
Claude Emond, Michael J DeVito, Linda S Birnbaum

Toxicol Appl Pharmacol· October 2021

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Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening.
Wei Qu, David M Crizer, Michael J DeVito, Suramya Waidyanatha, Menghang Xia

Toxicol In Vitro· June 2021

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Benchmark Concentrations for Untargeted Metabolomics Versus Transcriptomics for Liver Injury Compounds in In Vitro Liver Models.
David M Crizer, Sreenivasa C Ramaiahgari, Stephen S Ferguson, Julie R Rice, Paul E Dunlap, Michael J DeVito

Toxicol Sci· May 2021

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Evaluation of 5-day In Vivo Rat Liver and Kidney With High-throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes.
William M Gwinn, Scott S Auerbach, Fred Parham, Matthew D Stout, Suramya Waidyanatha, Michael J DeVito

Toxicol Sci· August 2020

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KRAS-retroviral fusion transcripts and gene amplification in arsenic-transformed, human prostate CAsE-PE cancer cells.
B Alex Merrick, Dhiral P Phadke, Meredith A Bostrom, Ruchir R Shah, Garron M Wright, Michael J DeVito

Toxicol Appl Pharmacol· June 2020

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