Publications by authors named "Michael Eldon"

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Safety, Tolerability, and Pharmacokinetics of RT234 (Vardenafil Inhalation Powder): A First-in-Human, Ascending Single- and Multiple-Dose Study in Healthy Subjects.
Michael A Eldon, Edwin L Parsley, Mari Maurer, Thomas E Tarara, Jerry Okikawa

J Aerosol Med Pulm Drug Deliv· August 2021

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Comparative bioavailability of inhaled treprostinil administered as LIQ861 and Tyvaso® in healthy subjects.
Robert F Roscigno, Toby Vaughn, Ed Parsley, Thomas Hunt, Michael A Eldon

Vascul Pharmacol· June 2021

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Human Abuse Potential of Oral NKTR-181 in Recreational Opioid Users: A Randomized, Double-Blind, Crossover Study.
Xue Ge, Jack E Henningfield, Suresh Siddhanti, Janet Jobes, Lin Lu, Michael A Eldon

Pain Med· February 2020

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Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors.
Sherwin K B Sy, Yen Lin Chia, Toufigh Gordi, Ute Hoch, Michael A Eldon

Cancer Chemother Pharmacol· May 2018

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Human Abuse Potential of the New Opioid Analgesic Molecule NKTR-181 Compared with Oxycodone.
Lynn Webster, Jack Henningfield, August R Buchhalter, Suresh Siddhanti, Lin Lu, Michael A Eldon

Pain Med· February 2018

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Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy.
Deborah Charych, Samira Khalili, Vidula Dixit, Peter Kirk, Thomas Chang, Michael Eldon

PLoS One· October 2017

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Pharmacologic Profile of Naloxegol, a Peripherally Acting -Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation.
Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza, Michael Eldon

J Pharmacol Exp Ther· May 2017

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Etirinotecan pegol administration is associated with lower incidences of neutropenia compared to irinotecan administration.
S Kenneth Sy, Theresa D Sweeney, Chunmei Ji, Ute Hoch, Michael A Eldon

Cancer Chemother Pharmacol· January 2017

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Safety, tolerability, pharmacokinetics, and pharmacodynamic effects of naloxegol at peripheral and central nervous system receptors in healthy male subjects: A single ascending-dose study.
Michael A Eldon, Alan R Kugler, Robert A Medve, Khanh Bui, Kathleen Butler

Clin Pharmacol Drug Dev· November 2015

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Safety, tolerability, and pharmacokinetics of multiple ascending doses of naloxegol.
Michael A Eldon, Alan R Kugler, Robert A Medve, Khanh Bui, Kathleen Butler

Clin Pharmacol Drug Dev· November 2015

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NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer.
Chris E Adkins, Mohamed I Nounou, Tanvirul Hye, Afroz S Mohammad, Tori Terrell-Hall, Michael A Eldon

BMC Cancer· October 2015

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Nonclinical pharmacokinetics and activity of etirinotecan pegol (NKTR-102), a long-acting topoisomerase 1 inhibitor, in multiple cancer models.
Ute Hoch, Carl-Michael Staschen, Randall K Johnson, Michael A Eldon

Cancer Chemother Pharmacol· December 2014

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A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation.
Lynn Webster, Sunita Dhar, Michael Eldon, Lorianne Masuoka, Jaakko Lappalainen

Pain· September 2013

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A multicenter, phase I, dose-escalation study to assess the safety, tolerability, and pharmacokinetics of etirinotecan pegol in patients with refractory solid tumors.
Gayle S Jameson, John T Hamm, Glen J Weiss, Carlos Alemany, Stephen Anthony, Michael A Eldon

Clin Cancer Res· January 2013

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Pharmacokinetics and tolerability of amikacin administered as BAY41-6551 aerosol in mechanically ventilated patients with gram-negative pneumonia and acute renal failure.
Charles-Edouard Luyt, Michael A Eldon, Heino Stass, Dennis Gribben, Kevin Corkery

J Aerosol Med Pulm Drug Deliv· August 2011

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Pharmacokinetics and tolerability of BAY41-6551 in subjects with chronic kidney disease.
Heino Stass, Kevin Corkery, Dennis Gribben, Michael A Eldon

J Aerosol Med Pulm Drug Deliv· August 2011

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Clinical pharmacokinetics and pharmacodynamics of inhaled insulin.
John S Patton, Julie G Bukar, Michael A Eldon

Clin Pharmacokinet· January 2005

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Lung deposition and pharmacokinetics of cyclosporine after aerosolization in lung transplant patients.
Gilbert J Burkart, Gerald C Smaldone, Michael A Eldon, Raman Venkataramanan, James Dauber

Pharm Res· February 2003

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The effect of food on the bioavailability of norethindrone and ethinyl estradiol from norethindrone acetate/ethinyl estradiol tablets intended for continuous hormone replacement therapy.
Rebecca A Boyd, Elizabeth A Zegarac, Michael A Eldon

J Clin Pharmacol· January 2003

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Improved lung delivery from a passive dry powder inhaler using an Engineered PulmoSphere powder.
Sarma P Duddu, Steven A Sisk, Yulia H Walter, Thomas E Tarara, Kevin R Trimble, Michael A Eldon

Pharm Res· May 2002

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