Publications by authors named "Michael Fill"

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Age-Dependent Effects of Muscle Resting Calcium on Fasting Blood Glucose: Implications for Prediabetes Risk.
Eshwar R Tammineni, Lourdes Figueroa, Michael Fill, Sheila Riazi, Carlo Manno

Endocrinol Diabetes Metab· May 2025

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Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans.
Bo Sun, Mingke Ni, Yanhui Li, Zhenpeng Song, Hui Wang, Michael Fill

Circulation· March 2025

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Alda-1 attenuation of binge alcohol-caused atrial arrhythmias through a novel mechanism of suppressed c-Jun N-terminal Kinase-2 activity.
Jiajie Yan, Saugat Khanal, Yuanyuan Cao, Nikola Ricchiuti, Alma Nani, Michael Fill

J Mol Cell Cardiol· December 2024

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Polarity profiling of porous architectures: solvatochromic dye encapsulation in metal-organic frameworks.
Heidi A Schwartz, Murat Atar, Matthias Spilles, Michael Fill, Manuel Ott

J Mater Chem C Mater· June 2024

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Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals.
Catherine Carvajal, Jiajie Yan, Alma Nani, Jaime DeSantiago, Xiaoping Wan, Michael Fill

J Membr Biol· April 2024

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Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation.
Allison Tambeaux, Yuriana Aguilar-Sánchez, Demetrio J Santiago, Madeleine Mascitti, Karyn M DiNovo, Michael Fill

Pflugers Arch· May 2023

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A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice.
Bo Sun, Mingke Ni, Shanshan Tian, Wenting Guo, Shitian Cai, Michael Fill

J Cell Physiol· August 2022

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Simulating cardiac Ca release units: effects of RyR cluster size and Ca buffers on diastolic Ca leak.
Michael Fill, Dirk Gillespie

Pflugers Arch· March 2021

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Cardiac ryanodine receptor calcium release deficiency syndrome.
Bo Sun, Jinjing Yao, Mingke Ni, Jinhong Wei, Xiaowei Zhong, Michael Fill

Sci Transl Med· February 2021

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Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation.
Jinjing Yao, Bo Sun, Adam Institoris, Xiaoqin Zhan, Wenting Guo, Michael Fill

Cell Rep· September 2020

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Diminished inhibition and facilitated activation of RyR2-mediated Ca release is a common defect of arrhythmogenic calmodulin mutations.
Mads T Søndergaard, Yingjie Liu, Malene Brohus, Wenting Guo, Alma Nani, Michael Fill

FEBS J· November 2019

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Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease.
Timothy F Musial, Elizabeth Molina-Campos, Linda A Bean, Natividad Ybarra, Ronen Borenstein, Michael Fill

Neurobiol Learn Mem· October 2018

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Ryanodine Receptor Open Times Are Determined in the Closed State.
Michael Fill, Dirk Gillespie

Biophys J· October 2018

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Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.
Xianlong Gao, Xiaomin Wu, Jiajie Yan, Jingqun Zhang, Weiwei Zhao, Michael Fill

Cardiovasc Res· April 2018

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Role of Stress Kinase JNK in Binge Alcohol-Evoked Atrial Arrhythmia.
Jiajie Yan, Justin K Thomson, Weiwei Zhao, Xianlong Gao, Fei Huang, Michael Fill

J Am Coll Cardiol· April 2018

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Stress Signaling JNK2 Crosstalk With CaMKII Underlies Enhanced Atrial Arrhythmogenesis.
Jiajie Yan, Weiwei Zhao, Justin K Thomson, Xianlong Gao, Dominic M DeMarco, Michael Fill

Circ Res· March 2018

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Sarcoplasmic Reticulum Ca Release Uses a Cascading Network of Intra-SR and Channel Countercurrents.
Vilmos Zsolnay, Michael Fill, Dirk Gillespie

Biophys J· January 2018

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Sarcoplasmic reticulum Ca, Mg, K, and Cl concentrations adjust quickly as heart rate changes.
Claudio Berti, Vilmos Zsolnay, Thomas R Shannon, Michael Fill, Dirk Gillespie

J Mol Cell Cardiol· February 2017

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Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity.
Akira Uehara, Takashi Murayama, Midori Yasukochi, Michael Fill, Minoru Horie

J Gen Physiol· February 2017

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The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor.
Mads Toft Søndergaard, Yingjie Liu, Kamilla Taunsig Larsen, Alma Nani, Xixi Tian, Michael Fill

J Biol Chem· January 2017

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Nebivolol suppresses cardiac ryanodine receptor-mediated spontaneous Ca2+ release and catecholaminergic polymorphic ventricular tachycardia.
Zhen Tan, Zhichao Xiao, Jinhong Wei, Jingqun Zhang, Qiang Zhou, Michael Fill

Biochem J· November 2016

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Approaching ryanodine receptor therapeutics from the calcin angle.
Josefina Ramos-Franco, Michael Fill

J Gen Physiol· May 2016

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Cytosolic Ca²⁺ buffering determines the intra-SR Ca²⁺ concentration at which cardiac Ca²⁺ sparks terminate.
Elisa Bovo, Stefan R Mazurek, Michael Fill, Aleksey V Zima

Cell Calcium· September 2015

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Non-β-blocking R-carvedilol enantiomer suppresses Ca2+ waves and stress-induced ventricular tachyarrhythmia without lowering heart rate or blood pressure.
Jingqun Zhang, Qiang Zhou, Chris D Smith, Haiyan Chen, Zhen Tan, Michael Fill

Biochem J· September 2015

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The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice.
Jingqun Zhang, Biyi Chen, Xiaowei Zhong, Tao Mi, Ang Guo, Michael Fill

Biochem J· July 2014

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