Publications by authors named "Michael Forgac"

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A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice.
Zhen Li, Mohammed A Alshagawi, Rebecca A Oot, Mariam K Alamoudi, Kevin Su, Michael Forgac

Oncotarget· August 2024

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Isoform a4 of the vacuolar ATPase a subunit promotes 4T1-12B breast cancer cell-dependent tumor growth and metastasis in vivo.
Kevin Su, Michael P Collins, Christina M McGuire, Mohammed A Alshagawi, Mariam K Alamoudi, Michael Forgac

J Biol Chem· October 2022

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Regulation and function of V-ATPases in physiology and disease.
Michael P Collins, Michael Forgac

Biochim Biophys Acta Biomembr· December 2020

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AKT Ser/Thr kinase increases V-ATPase-dependent lysosomal acidification in response to amino acid starvation in mammalian cells.
Michael P Collins, Laura A Stransky, Michael Forgac

J Biol Chem· July 2020

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Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells.
Christina M McGuire, Michael P Collins, GeHong Sun-Wada, Yoh Wada, Michael Forgac

J Biol Chem· July 2019

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A new twist to V-ATPases and cancer.
Michael Forgac

Oncotarget· August 2018

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Regulation of V-ATPase Assembly in Nutrient Sensing and Function of V-ATPases in Breast Cancer Metastasis.
Michael P Collins, Michael Forgac

Front Physiol· July 2018

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Glucose starvation increases V-ATPase assembly and activity in mammalian cells through AMP kinase and phosphatidylinositide 3-kinase/Akt signaling.
Christina M McGuire, Michael Forgac

J Biol Chem· June 2018

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Regulation of V-ATPase activity.
Christina McGuire, Laura Stransky, Kristina Cotter, Michael Forgac

Front Biosci (Landmark Ed)· January 2017

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Regulation of V-ATPase assembly and function of V-ATPases in tumor cell invasiveness.
Christina McGuire, Kristina Cotter, Laura Stransky, Michael Forgac

Biochim Biophys Acta· August 2016

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The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.
Kristina Cotter, Rachel Liberman, GeHong Sun-Wada, Yoh Wada, Dennis Sgroi, Michael Forgac

Oncotarget· July 2016

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The Function of V-ATPases in Cancer.
Laura Stransky, Kristina Cotter, Michael Forgac

Physiol Rev· July 2016

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Amino Acid Availability Modulates Vacuolar H+-ATPase Assembly.
Laura A Stransky, Michael Forgac

J Biol Chem· November 2015

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Recent Insights into the Structure, Regulation, and Function of the V-ATPases.
Kristina Cotter, Laura Stransky, Christina McGuire, Michael Forgac

Trends Biochem Sci· October 2015

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Activity of plasma membrane V-ATPases is critical for the invasion of MDA-MB231 breast cancer cells.
Kristina Cotter, Joseph Capecci, Souad Sennoune, Markus Huss, Martin Maier, Michael Forgac

J Biol Chem· February 2015

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Regulated assembly of vacuolar ATPase is increased during cluster disruption-induced maturation of dendritic cells through a phosphatidylinositol 3-kinase/mTOR-dependent pathway.
Rachel Liberman, Sarah Bond, Mara G Shainheit, Miguel J Stadecker, Michael Forgac

J Biol Chem· January 2014

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The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.
Joseph Capecci, Michael Forgac

J Biol Chem· November 2013

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Structural analysis of the N-terminal domain of subunit a of the yeast vacuolar ATPase (V-ATPase) using accessibility of single cysteine substitutions to chemical modification.
Rachel Liberman, Kristina Cotter, James D Baleja, Michael Forgac

J Biol Chem· August 2013

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Definition of membrane topology and identification of residues important for transport in subunit a of the vacuolar ATPase.
Masashi Toei, Satoko Toei, Michael Forgac

J Biol Chem· October 2011

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Regulation and isoform function of the V-ATPases.
Masashi Toei, Regina Saum, Michael Forgac

Biochemistry· June 2010

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Heme-binding protein HRG-1 is induced by insulin-like growth factor I and associates with the vacuolar H+-ATPase to control endosomal pH and receptor trafficking.
Katie M O'Callaghan, Veronica Ayllon, Jean O'Keeffe, Yanru Wang, Orla T Cox, Michael Forgac

J Biol Chem· January 2010

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Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cells.
Ayana Hinton, Souad R Sennoune, Sarah Bond, Min Fang, Moshe Reuveni, Michael Forgac

J Biol Chem· June 2009

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The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the vacuolar (H+)-ATPase in yeast.
Sarah Bond, Michael Forgac

J Biol Chem· December 2008

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Function and subunit interactions of the N-terminal domain of subunit a (Vph1p) of the yeast V-ATPase.
Jie Qi, Michael Forgac

J Biol Chem· July 2008

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Analysis of the membrane topology of transmembrane segments in the C-terminal hydrophobic domain of the yeast vacuolar ATPase subunit a (Vph1p) by chemical modification.
Yanru Wang, Masashi Toei, Michael Forgac

J Biol Chem· July 2008

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