Publications by authors named "Michael J Edel"

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An Optimized Method to Produce Human-Induced Pluripotent Stem Cell-Derived Limbal Stem Cells Easily Adaptable for Clinical Use.
Michael J Edel, Helena Sarret Casellas, Jordi Requena Osete, Núria Nieto-Nicolau, Francisco Arnalich-Montiel

Stem Cells Dev· February 2025

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Blocking IL-6 signaling prevents astrocyte-induced neurodegeneration in an iPSC-based model of Parkinson's disease.
Meritxell Pons-Espinal, Lucas Blasco-Agell, Irene Fernandez-Carasa, Pol Andrés-Benito, Angelique di Domenico, Michael J Edel

JCI Insight· February 2024

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Proteomic Analysis of Human iPSC-Derived Neural Stem Cells and Motor Neurons Identifies Proteasome Structural Alterations.
Iñaki Álvarez, Adrián Tirado-Herranz, Belén Alvarez-Palomo, Jordi Requena Osete, Michael J Edel

Cells· December 2023

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Exploiting endocytosis for transfection of mRNA for cytoplasmatic delivery using cationic gold nanoparticles.
Muriel F Gustà, Michael J Edel, Vivian A Salazar, Belén Alvarez-Palomo, Manel Juan

Front Immunol· May 2023

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A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries.
Hoda Elkhenany, Pablo Bonilla, Esther Giraldo, Ana Alastrue Agudo, Michael J Edel

Biomedicines· December 2021

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A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells.
Ana Belén Alvarez-Palomo, Jordi Requena-Osete, Raul Delgado-Morales, Victoria Moreno-Manzano, Carme Grau-Bove, Michael J Edel

Stem Cells· July 2021

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Induced pluripotent stem cell-derived lung alveolar epithelial type II cells reduce damage in bleomycin-induced lung fibrosis.
Belén Alvarez-Palomo, Luis Ignacio Sanchez-Lopez, Yuben Moodley, Michael J Edel, Anna Serrano-Mollar

Stem Cell Res Ther· June 2020

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Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases.
Belen Alvarez-Palomo, Carme Barrot-Feixat, Helena Sarret, Jordi Requena, Montserrat Pau, Michael J Edel

Oncotarget· October 2019

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Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling.
Jordi Requena, Ana Belen Alvarez-Palomo, Montserrat Codina-Pascual, Raul Delgado-Morales, Sebastian Moran, Michael J Edel

Stem Cells· April 2019

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Adapting Cord Blood Collection and Banking Standard Operating Procedures for HLA-Homozygous Induced Pluripotent Stem Cells Production and Banking for Clinical Application.
Belén Alvarez-Palomo, Joaquim Vives, Ricardo P P Casaroli-Marano, Susana G G Gomez, Luciano Rodriguez Gómez, Michael J Edel

J Clin Med· April 2019

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iPS-Cell Technology and the Problem of Genetic Instability-Can It Ever Be Safe for Clinical Use?
Stephen W Attwood, Michael J Edel

J Clin Med· February 2019

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Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons.
Raquel Martín-Ibáñez, Mónica Pardo, Albert Giralt, Andrés Miguez, Inés Guardia, Michael J Edel

Development· April 2017

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Effects of the Post-Spinal Cord Injury Microenvironment on the Differentiation Capacity of Human Neural Stem Cells Derived from Induced Pluripotent Stem Cells.
Clara López-Serrano, Abel Torres-Espín, Joaquim Hernández, Ana B Alvarez-Palomo, Jordi Requena, Michael J Edel

Cell Transplant· October 2016

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Prospects for clinical use of reprogrammed cells for autologous treatment of macular degeneration.
Ana Belen Alvarez Palomo, Samuel McLenachan, Fred K Chen, Lyndon Da Cruz, Rodney J Dilley, Michael J Edel

Fibrogenesis Tissue Repair· May 2015

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The Possible Future Roles for iPSC-Derived Therapy for Autoimmune Diseases.
Meilyn Hew, Kevin O'Connor, Michael J Edel, Michaela Lucas

J Clin Med· May 2015

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Bioengineering and Stem Cell Technology in the Treatment of Congenital Heart Disease.
Alexis Bosman, Michael J Edel, Gillian Blue, Rodney J Dilley, Richard P Harvey

J Clin Med· April 2015

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Myogenic Precursors from iPS Cells for Skeletal Muscle Cell Replacement Therapy.
Isart Roca, Jordi Requena, Michael J Edel, Ana Belén Alvarez-Palomo

J Clin Med· January 2015

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mRNA transfection of mouse and human neural stem cell cultures.
Samuel McLenachan, Dan Zhang, Ana Belén Alvarez Palomo, Michael J Edel, Fred K Chen

PLoS One· September 2014

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The Power and the Promise of Cell Reprogramming: Personalized Autologous Body Organ and Cell Transplantation.
Ana Belen Alvarez Palomo, Michaela Lucas, Rodney J Dilley, Samuel McLenachan, Fred Kuanfu Chen, Michael J Edel

J Clin Med· April 2014

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Plant hormones increase efficiency of reprogramming mouse somatic cells to induced pluripotent stem cells and reduce tumorigenicity.
Ana Belén Alvarez Palomo, Samuel McLenachan, Jordi Requena Osete, Cristina Menchón, Carme Barrot, Michael J Edel

Stem Cells Dev· March 2014

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Cyclin A1 is essential for setting the pluripotent state and reducing tumorigenicity of induced pluripotent stem cells.
Samuel McLenachan, Cristina Menchón, Angel Raya, Antonella Consiglio, Michael J Edel

Stem Cells Dev· October 2012

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The cell cycle inhibitor p27Kip¹ controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist.
Cristina Menchón, Michael J Edel, Juan Carlos Izpisua Belmonte

Cell Cycle· May 2011

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A protocol to assess cell cycle and apoptosis in human and mouse pluripotent cells.
Michael J Edel, Cristina Menchon, Jose Miguel Andres Vaquero, Juan Carlos Izpisua Belmonte

Cell Commun Signal· April 2011

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Rem2 GTPase controls proliferation and apoptosis of neurons during embryo development.
Michael J Edel, Stéphanie Boué, Cristina Menchon, Adriana Sánchez-Danés, Juan Carlos Izpisua Belmonte

Cell Cycle· September 2010

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The cell cycle and pluripotency: Is there a direct link?
Michael J Edel, Juan Carlos Izpisua Belmonte

Cell Cycle· July 2010

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