Publications by authors named "Michael J Pether"

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Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists.
Iain M McDonald, Carol Austin, Ildiko M Buck, David J Dunstone, John Gaffen, Michael J Pether

J Med Chem· October 2007

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Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion.
Iain M McDonald, James W Black, Ildiko M Buck, David J Dunstone, Eric P Griffin, Michael J Pether

J Med Chem· June 2007

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Novel, achiral 1,3,4-benzotriazepine analogues of 1,4-benzodiazepine-based CCK(2) antagonists that display high selectivity over CCK(1) receptors.
Iain M McDonald, Carol Austin, Ildiko M Buck, David J Dunstone, Eric Griffin, Michael J Pether

J Med Chem· April 2006

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Scaffold hopping with molecular field points: identification of a cholecystokinin-2 (CCK2) receptor pharmacophore and its use in the design of a prototypical series of pyrrole- and imidazole-based CCK2 antagonists.
Caroline M R Low, Ildiko M Buck, Tracey Cooke, Julia R Cushnir, S Barret Kalindjian, Michael J Pether

J Med Chem· November 2005

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Optimization of the in vitro and in vivo properties of a novel series of 2,4,5-trisubstituted imidazoles as potent cholecystokinin-2 (CCK2) antagonists.
Ildiko M Buck, James W Black, Tracey Cooke, David J Dunstone, John D Gaffen, Michael J Pether

J Med Chem· November 2005

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omega-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H(3) receptor antagonists.
Matthew J Tozer, Ildiko M Buck, Tracey Cooke, S Barret Kalindjian, Michael J Pether

Bioorg Med Chem· February 2002

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