Publications by authors named "Michael Kalafatis"

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Quercetin Increases Expression of Membrane-TRAIL in Glioblastoma Cells Resulting in Apoptosis.
Erin M Thorpe, Gaëlle Muller-Greven, Jamila Hirbawi, Candece L Gladson, Michael Kalafatis

Cancers (Basel)· September 2025

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Exploring the anti-cancer effects of through network pharmacology and molecular modeling.
Erin M Thorpe, Michael Kalafatis, Yan Xu

Genes Dis· November 2023

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COVID-19: A Serious Vascular Disease with Primary Symptoms of a Respiratory Ailment.
Michael Kalafatis

J Appl Lab Med· September 2021

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Ursolic Acid Promotes the Sensitization of rhTRAIL-resistant Triple-negative Breast Cancer.
Jasmine M Manouchehri, Michael Kalafatis

Anticancer Res· December 2018

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Sensitization of recombinant human tumor necrosis factor-related apoptosis-inducing ligand-resistant malignant melanomas by quercetin.
Katherine A Turner, Jasmine M Manouchehri, Michael Kalafatis

Melanoma Res· August 2018

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TRAIL-Induced Apoptosis in TRAIL-Resistant Breast Carcinoma Through Quercetin Cotreatment.
Jasmine M Manouchehri, Katherine A Turner, Michael Kalafatis

Breast Cancer (Auckl)· January 2018

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Sensitization of rhTRAIL-resistant Triple-negative Breast Carcinoma Through Silibinin Co-Treatment.
Jasmine M Manouchehri, Michael Kalafatis

Anticancer Res· December 2017

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The Case Back on the TRAIL: Death Receptors as Markers for rhTRAIL Sensitivity.
Katherine A Turner, Michael Kalafatis

J Appl Lab Med· September 2017

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Spellbinding Effects of the Acidic COOH-Terminus of Factor Va Heavy Chain on Prothrombinase Activity and Function.
Jamila Hirbawi, Michael Kalafatis

ACS Omega· September 2017

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The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin.
Joesph R Wiencek, Jamila Hirbawi, Vivien C Yee, Michael Kalafatis

J Biol Chem· January 2016

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Amino acid region 1000-1008 of factor V is a dynamic regulator for the emergence of procoagulant activity.
Joesph R Wiencek, Mahesheema Na, Jamila Hirbawi, Michael Kalafatis

J Biol Chem· December 2013

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Cleavage at both Arg306 and Arg506 is required and sufficient for timely and efficient inactivation of factor Va by activated protein C.
Melissa A Barhoover, Michael Kalafatis

Blood Coagul Fibrinolysis· June 2011

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Contribution of amino acid region 659-663 of Factor Va heavy chain to the activity of factor Xa within prothrombinase .
Jamila Hirbawi, John L Vaughn, Michael A Bukys, Hans L Vos, Michael Kalafatis

Biochemistry· October 2010

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Cooperative regulation of the activity of factor Xa within prothrombinase by discrete amino acid regions from factor Va heavy chain.
Melissa A Barhoover, Tivadar Orban, Michael A Bukys, Michael Kalafatis

Biochemistry· December 2008

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Contribution of amino acid region 334-335 from factor Va heavy chain to the catalytic efficiency of prothrombinase.
Melissa A Barhoover, Tivadar Orban, Daniel O Beck, Michael A Bukys, Michael Kalafatis

Biochemistry· July 2008

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Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase.
Jamila Hirbawi, Michael A Bukys, Melissa A Barhoover, Evrim Erdogan, Michael Kalafatis

Biochemistry· July 2008

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The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase.
Michael A Bukys, Tivadar Orban, Paul Y Kim, Michael E Nesheim, Michael Kalafatis

Thromb Haemost· March 2008

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Identification of an inactivating cleavage site for alpha-thrombin on the heavy chain of factor Va.
Evrim Erdogan, Michael A Bukys, Thomas Orfeo, Kenneth G Mann, Michael Kalafatis

Thromb Haemost· November 2007

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A control switch for prothrombinase: characterization of a hirudin-like pentapeptide from the COOH terminus of factor Va heavy chain that regulates the rate and pathway for prothrombin activation.
Michael A Bukys, Paul Y Kim, Michael E Nesheim, Michael Kalafatis

J Biol Chem· December 2006

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The structural integrity of anion binding exosite I of thrombin is required and sufficient for timely cleavage and activation of factor V and factor VIII.
Michael A Bukys, Tivadar Orban, Paul Y Kim, Daniel O Beck, Michael E Nesheim, Michael Kalafatis

J Biol Chem· July 2006

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Completed three-dimensional model of human coagulation factor va. Molecular dynamics simulations and structural analyses.
Tivadar Orban, Michael Kalafatis, Valentin Gogonea

Biochemistry· October 2005

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Incorporation of factor Va into prothrombinase is required for coordinated cleavage of prothrombin by factor Xa.
Michael A Bukys, Melissa A Blum, Paul Y Kim, Nicole Brufatto, Michael E Nesheim, Michael Kalafatis

J Biol Chem· July 2005

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Coagulation factor V: a plethora of anticoagulant molecules.
Michael Kalafatis

Curr Opin Hematol· March 2005

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The contribution of amino acid region ASP695-TYR698 of factor V to procofactor activation and factor Va function.
Daniel O Beck, Michael A Bukys, Lisam S Singh, Katalin A Szabo, Michael Kalafatis

J Biol Chem· January 2004

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Structural requirements for expression of factor Va activity.
Michael Kalafatis, Daniel O Beck, Kenneth G Mann

J Biol Chem· August 2003

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