Publications by authors named "Michael Karlsson"

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Diffuse traumatic brain injury in mice is associated with a transient mismatch of cerebral blood flow and energy metabolism.
Sertan Arkan, Michael Gottschalk, Saema Ansar, Jesper Peter Bömers, Johannes Ehinger, Michael Karlsson

J Cereb Blood Flow Metab· January 2026

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Effect of dimethyl fumarate on mitochondrial metabolism in a pediatric porcine model of asphyxia-induced in-hospital cardiac arrest.
Sarah Piel, Meagan J McManus, Kristina N Heye, Forrest Beaulieu, Hossein Fazelinia, Michael Karlsson

Sci Rep· June 2024

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Correlation of mitochondrial respiration in platelets, peripheral blood mononuclear cells and muscle fibers.
Emil Westerlund, Sigurður E Marelsson, Michael Karlsson, Fredrik Sjövall, Imen Chamkha

Heliyon· March 2024

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Mitochondrial function in peripheral blood cells across the human lifespan.
Johannes K Ehinger, Emil Westerlund, Eleonor Åsander Frostner, Michael Karlsson, Gesine Paul

NPJ Aging· February 2024

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Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat.
Sarah Piel, Joanna I Janowska, J Laurenson Ward, Meagan J McManus, Danielle I Aronowitz, Michael Karlsson

Mol Cell Biochem· June 2023

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Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Sarah Piel, Joanna I Janowska, J Laurenson Ward, Meagan J McManus, Joshua S Jose, Michael Karlsson

Sci Rep· November 2022

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Predictors of outcome in children with disorders of mitochondrial metabolism in the pediatric intensive care unit.
Johannes K Ehinger, Michael Karlsson, Fredrik Sjövall, Märta Leffler, Shana E McCormack

Pediatr Res· December 2021

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Evaluation of Diffusion Tensor Imaging and Fluid Based Biomarkers in a Large Animal Trial of Cyclosporine in Focal Traumatic Brain Injury.
Michael Karlsson, Zhihui Yang, Sanjeev Chawla, Nile Delso, Bryan Pukenas

J Neurotrauma· June 2021

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Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model.
Kumaran Senthil, Ryan W Morgan, Marco M Hefti, Michael Karlsson, Andrew J Lautz

Resusc Plus· June 2021

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Randomized blinded trial of automated REBOA during CPR in a porcine model of cardiac arrest.
Markus Harboe Olsen, Niels D Olesen, Michael Karlsson, Theodore Holmlöv, Lars Søndergaard

Resuscitation· March 2021

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Epinephrine's effects on cerebrovascular and systemic hemodynamics during cardiopulmonary resuscitation.
Constantine D Mavroudis, Tiffany S Ko, Ryan W Morgan, Lindsay E Volk, William P Landis, Michael Karlsson

Crit Care· September 2020

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Axonal transport dysfunction of mitochondria in traumatic brain injury: A novel therapeutic target.
Samuel S Shin, Michael Karlsson, Vanessa M Mazandi, Abhay Ranganathan, Thomas Hallowell

Exp Neurol· July 2020

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Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug.
Joanna I Janowska, Sarah Piel, Nahima Saliba, Claire D Kim, David H Jang, Michael Karlsson

Toxicol In Vitro· June 2020

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Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial.
Alexandra M Marquez, Ryan W Morgan, Tiffany Ko, William P Landis, Marco M Hefti, Michael Karlsson

J Am Heart Assoc· May 2020

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Real-time neurochemical measurement of dynamic metabolic events during cardiac arrest and resuscitation in a porcine model.
Sally A N Gowers, Isabelle C Samper, De-Shaine R K Murray, Georgia K Smith, Sarah Jeyaprakash, Michael Karlsson

Analyst· March 2020

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Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients.
Jesper Kelsen, Michael Karlsson, Magnus J Hansson, Zhihui Yang, Walter Fischer

J Neurotrauma· December 2019

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Hemodynamic-Directed Cardiopulmonary Resuscitation Improves Neurologic Outcomes and Mitochondrial Function in the Heart and Brain.
Andrew J Lautz, Ryan W Morgan, Michael Karlsson, Constantine D Mavroudis, Tiffany S Ko

Crit Care Med· March 2019

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Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury.
Michael Karlsson, Bryan Pukenas, Sanjeev Chawla, Johannes K Ehinger, Ross Plyler

J Neurotrauma· January 2019

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Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine.
Constantine D Mavroudis, Michael Karlsson, Tiffany Ko, Marco Hefti, Javier I Gentile

Eur J Cardiothorac Surg· July 2018

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Pulmonary Vasodilator Therapy in Shock-associated Cardiac Arrest.
Ryan W Morgan, Robert M Sutton, Michael Karlsson, Andrew J Lautz, Constantine D Mavroudis

Am J Respir Crit Care Med· April 2018

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Hospitalizations for mitochondrial disease across the lifespan in the U.S.
Shana E McCormack, Rui Xiao, Todd J Kilbaugh, Michael Karlsson, Rebecca D Ganetzky

Mol Genet Metab· June 2017

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Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction - An in vivo large animal model.
Michael Karlsson, Johannes K Ehinger, Sarah Piel, Fredrik Sjövall, Johanna Henriksnäs

Mitochondrion· November 2016

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Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency.
Johannes K Ehinger, Sarah Piel, Rhonan Ford, Michael Karlsson, Fredrik Sjövall

Nat Commun· August 2016

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Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction.
Michael A Ferguson, Robert M Sutton, Michael Karlsson, Fredrik Sjövall, Lance B Becker

J Bioenerg Biomembr· June 2016

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Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury.
Todd J Kilbaugh, Michael Karlsson, Ann-Christine Duhaime, Magnus J Hansson, Eskil Elmer

Mitochondrion· January 2016

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