Publications by authors named "Michael Kyba"

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Matrix metalloproteinases are hallmark early biomarkers and therapeutic targets in FSHD.
Usuk Jung, Erdong Wei, Haseeb Ahsan, Ana Mitanoska, Kenric Chen, Michael Kyba

JCI Insight· November 2025

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Modeling CIC::DUX4 sarcoma reveals oncogene-mediated MHCI-dependent immune evasion.
Ajay Ram Vachanaram, Erdong Wei, Ana Mitanoska, William Bassett, Michael Kyba

Mol Cancer· November 2025

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Preclinical quality, safety, and efficacy of a CGMP iPSC-derived myogenic progenitor product for the treatment of muscular dystrophies.
Karim Azzag, Alessandro Magli, James Kiley, Darin Sumstad, Diane Kadidlo, Michael Kyba

Mol Ther· October 2025

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Estrogen Receptor Regulates Male Satellite Cells in a Female, but Not Male, Environment.
Ahmed S Shams, Brian P Sullivan, Erik A Toso, Dawn A Lowe, Michael Kyba

Cells· October 2025

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Long-Term Engraftment and Satellite Cell Expansion from Human PSC Teratoma-Derived Myogenic Progenitors.
Zahra Khosrowpour, Nivedha Ramaswamy, Elise N Engquist, Berkay Dincer, Alisha M Shah, Michael Kyba

Cells· July 2025

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Development of p300-targeting degraders with enhanced selectivity and onset of degradation.
Graham P Marsh, Mark S Cooper, Sean Goggins, Stephen J Reynolds, Dean F Wheeler, Michael Kyba

RSC Med Chem· May 2025

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Dux Is Dispensable for Skeletal Muscle Regeneration: A Study Inspired by a "Red Flagged" Publication and Editorial Oversight.
Kenric Chen, Erdong Wei, Ana Mitanoska, Micah D Gearhart, Michael Kyba

Cells· May 2025

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Estradiol deficiency as a consequence of aging contributes to the depletion of the satellite cell pool in female mice.
Brian P Sullivan, Alexie A Larson, Ahmed S Shams, Shawna L McMillin, Mara C Ebeling, Michael Kyba

Aging Cell· April 2025

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When everything is a master regulator, nothing is.
Robert S Krauss, Michael Kyba

Mol Biol Cell· March 2025

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Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma.
Erdong Wei, Ana Mitanoska, Quinn O'Brien, Kendall Porter, MacKenzie Molina, Michael Kyba

Mol Cancer· October 2024

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Multiparametric identification of putative senescent cells in skeletal muscle via mass cytometry.
Yijia Li, Nameera Baig, Daniel Roncancio, Kris Elbein, Dawn Lowe, Michael Kyba

Cytometry A· August 2024

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Cardiac Development Long Non-Coding RNA () Is Activated during Human Heart Development and Contributes to Cardiac Specification and Homeostasis.
Isabela T Pereira, Rubens Gomes-Júnior, Aruana Hansel-Frose, Rhaíza S V França, Man Liu, Michael Kyba

Cells· June 2024

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The homeobox transcription factor DUXBL controls exit from totipotency.
Maria Vega-Sendino, Felipe F Lüttmann, Teresa Olbrich, Yanpu Chen, Carsten Kuenne, Michael Kyba

Nat Genet· April 2024

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Skin muscle is the initial site of viral replication for arboviral bunyavirus infection.
Christine A Schneider, Jacqueline M Leung, Paola Carolina Valenzuela-Leon, Natalya A Golviznina, Erik A Toso, Michael Kyba

Nat Commun· February 2024

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Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain.
Fikru B Bedada, Brian R Thompson, Jennifer L Mikkila, Sunny S-K Chan, Si Ho Choi, Michael Kyba

Sci Rep· February 2024

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Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Darko Bosnakovski, Erik A Toso, Elizabeth T Ener, Micah D Gearhart, Lulu Yin, Michael Kyba

iScience· October 2023

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Facioscapulohumeral muscular dystrophy's game of homeodomains: therapy wants a biomarker as a sword wants a whetstone.
Michael Kyba, Darko Bosnakovski

Brain Commun· September 2023

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Genetically prolonged beige fat in male mice confers long-lasting metabolic health.
Ruifan Wu, Jooman Park, Yanyu Qian, Zuoxiao Shi, Ruoci Hu, Michael Kyba

Nat Commun· May 2023

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The Satellite Cell Colony Forming Cell Assay as a Tool to Measure Self-Renewal and Differentiation Potential.
Ahmed S Shams, Michael Kyba

Methods Mol Biol· April 2023

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DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Raghav Ramabadran, Jarey H Wang, Jaime M Reyes, Anna G Guzman, Sinjini Gupta, Michael Kyba

Nat Cell Biol· April 2023

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Proliferation and Maturation: Janus and the Art of Cardiac Tissue Engineering.
Bhairab N Singh, Dogacan Yucel, Bayardo I Garay, Elena G Tolkacheva, Michael Kyba

Circ Res· February 2023

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Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes.
Bayardo I Garay, Sophie Givens, Phablo Abreu, Man Liu, Doğacan Yücel, Michael Kyba

Stem Cell Reports· January 2023

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Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Darko Bosnakovski, Erik A Toso, Elizabeth T Ener, Micah D Gearhart, Lulu Yin, Michael Kyba

bioRxiv· January 2023

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Not young but still immature: a HIF-1α-mediated maturation checkpoint in regenerating muscle.
Rahagir Salekeen, Michael Kyba

J Clin Invest· December 2022

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The chemokine receptor CXCR4 regulates satellite cell activation, early expansion, and self-renewal, in response to skeletal muscle injury.
Ahmed S Shams, Robert W Arpke, Micah D Gearhart, Johannes Weiblen, Ben Mai, Michael Kyba

Front Cell Dev Biol· September 2022

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