Publications by authors named "Michael L Citro"

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Dual mechanisms of HNO generation by a nitroxyl prodrug of the diazeniumdiolate (NONOate) class.
Daniela Andrei, Debra J Salmon, Sonia Donzelli, Azadeh Wahab, John R Klose, Michael L Citro

J Am Chem Soc· November 2010

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Glycosylated PROLI/NO derivatives as nitric oxide prodrugs.
Rahul S Nandurdikar, Anna E Maciag, Sam Y Hong, Harinath Chakrapani, Michael L Citro

Org Lett· January 2010

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Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound.
Rahul S Nandurdikar, Anna E Maciag, Michael L Citro, Paul J Shami, Larry K Keefer

Bioorg Med Chem Lett· May 2009

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Aryl bis(diazeniumdiolates): potent inducers of S-glutathionylation of cellular proteins and their in vitro antiproliferative activities.
Daniela Andrei, Anna E Maciag, Harinath Chakrapani, Michael L Citro, Larry K Keefer

J Med Chem· December 2008

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Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.
Harinath Chakrapani, Ravi C Kalathur, Anna E Maciag, Michael L Citro, Xinhua Ji

Bioorg Med Chem· November 2008

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Cell-permeable esters of diazeniumdiolate-based nitric oxide prodrugs.
Harinath Chakrapani, Anna E Maciag, Michael L Citro, Larry K Keefer, Joseph E Saavedra

Org Lett· November 2008

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Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.
Carlos A Valdez, Joseph E Saavedra, Brett M Showalter, Keith M Davies, Thomas C Wilde, Michael L Citro

J Med Chem· July 2008

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Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound.
Harinath Chakrapani, Thomas C Wilde, Michael L Citro, Michael M Goodblatt, Larry K Keefer

Bioorg Med Chem· March 2008

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Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
Carlos A Velázquez, Qiao-Hong Chen, Michael L Citro, Larry K Keefer, Edward E Knaus

J Med Chem· March 2008

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Nitric oxide prodrugs: diazeniumdiolate anions of hindered secondary amines.
Harinath Chakrapani, Brett M Showalter, Michael L Citro, Larry K Keefer, Joseph E Saavedra

Org Lett· October 2007

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O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies.
Carlos A Velázquez, P N Praveen Rao, Michael L Citro, Larry K Keefer, Edward E Knaus

Bioorg Med Chem· July 2007

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Nitric oxide-releasing fabrics and other acrylonitrile-based diazeniumdiolates.
Frank DeRosa, Melina R Kibbe, Samer F Najjar, Michael L Citro, Larry K Keefer

J Am Chem Soc· April 2007

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Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450.
Keiko Inami, Raymond W Nims, Aloka Srinivasan, Michael L Citro, Joseph E Saavedra

Nitric Oxide· June 2006

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Nitric oxide releasing polyurethanes with covalently linked diazeniumdiolated secondary amines.
Melissa M Reynolds, Joseph A Hrabie, Bong K Oh, Jeffrey K Politis, Michael L Citro

Biomacromolecules· March 2006

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PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.
Joseph E Saavedra, Aloka Srinivasan, Gregory S Buzard, Keith M Davies, David J Waterhouse, Michael L Citro

J Med Chem· February 2006

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Injectable formulation of disodium 1-[2-(carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate (PROLI/NO), an ultrafast nitric oxide donor prodrug.
David J Waterhouse, Joseph E Saavedra, Keith M Davies, Michael L Citro, Xia Xu

J Pharm Sci· January 2006

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Diazeniumdiolate ions as leaving groups in anomeric displacement reactions: a protection-deprotection strategy for ionic diazeniumdiolates.
Brett M Showalter, Melissa M Reynolds, Carlos A Valdez, Joseph E Saavedra, Keith M Davies, Michael L Citro

J Am Chem Soc· October 2005

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Carbon-bound diazeniumdiolates from the reaction of nitric oxide with amidines.
Joseph A Hrabie, Michael L Citro, Gwendolyn N Chmurny, Larry K Keefer

J Org Chem· September 2005

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Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion.
Joseph E Saavedra, D Scott Bohle, Kamilah N Smith, Clifford George, Jeffrey R Deschamps, Michael L Citro

J Am Chem Soc· October 2004

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Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug.
Victoria J Findlay, Danyelle M Townsend, Joseph E Saavedra, Gregory S Buzard, Michael L Citro

Mol Pharmacol· May 2004

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Nitric oxide does not mediate but inhibits transformation and tumor phenotype.
Arindam Dhar, June M Brindley, Cristi Stark, Michael L Citro, Larry K Keefer

Mol Cancer Ther· December 2003

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JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.
Paul J Shami, Joseph E Saavedra, Lai Y Wang, Challice L Bonifant, Bhalchandra A Diwan, Michael L Citro

Mol Cancer Ther· April 2003

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Preparation and reactivity of O2-sulfonated diazeniumdiolates.
Raechelle A D'Sa, Yuhong Wang, Patrick H Ruane, Brett M Showalter, Joseph E Saavedra, Michael L Citro

J Org Chem· January 2003

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Mechanistic insight into exclusive nitric oxide recovery from a carbon-bound diazeniumdiolate.
Ernst V Arnold, Michael L Citro, Evelyn A Saavedra, Keith M Davies, Larry K Keefer

Nitric Oxide· September 2002

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A nitric oxide-releasing polydiazeniumdiolate derived from acetonitrile.
Ernst V Arnold, Michael L Citro, Larry K Keefer, Joseph A Hrabie

Org Lett· April 2002

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