Publications by authors named "Michael L Hutton"

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Discovery and clinical translation of ceperognastat, an O-GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease.
William Kielbasa, Paul Goldsmith, Kevin B Donnelly, Hugh N Nuthall, Sergey Shcherbinin, Michael L Hutton

Alzheimers Dement (N Y)· December 2024

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Imbalance in the response of pre- and post-synaptic components to amyloidopathy.
Terri-Leigh Stephen, Francesco Tamagnini, Judith Piegsa, Katherine Sung, Joshua Harvey, Michael L Hutton

Sci Rep· October 2019

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Alzheimer's Disease-Related Dementias Summit 2016: National research priorities.
Roderick A Corriveau, Walter J Koroshetz, Jordan T Gladman, Sophia Jeon, Debra Babcock, Michael L Hutton

Neurology· December 2017

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Altered Synapse Stability in the Early Stages of Tauopathy.
Johanna S Jackson, Jonathan Witton, James D Johnson, Zeshan Ahmed, Mark Ward, Michael L Hutton

Cell Rep· March 2017

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Conformation determines the seeding potencies of native and recombinant Tau aggregates.
Benjamin Falcon, Annalisa Cavallini, Rachel Angers, Sarah Glover, Tracey K Murray, Michael L Hutton

J Biol Chem· January 2015

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Anti-Aβ antibody target engagement: commentary regarding Watt et al. Acta Neuropathol 127:803-810 (2014).
Eric Siemers, Robert A Dean, Ronald B DeMattos, Michael L Hutton, Kaj Blennow

Acta Neuropathol· October 2014

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Astrocytes and neuroinflammation in Alzheimer's disease.
Emma C Phillips, Cara L Croft, Ksenia Kurbatskaya, Michael J O'Neill, Michael L Hutton

Biochem Soc Trans· October 2014

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Recommendations of the Alzheimer's disease-related dementias conference.
Thomas J Montine, Walter J Koroshetz, Debra Babcock, Dennis W Dickson, Wendy R Galpern, Michael L Hutton

Neurology· August 2014

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A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity.
Zeshan Ahmed, Jane Cooper, Tracey K Murray, Katya Garn, Emily McNaughton, Michael L Hutton

Acta Neuropathol· May 2014

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SLC20A2 and THAP1 deletion in familial basal ganglia calcification with dystonia.
Matt Baker, Audrey J Strongosky, Monica Y Sanchez-Contreras, Shan Yang, Will Ferguson, Michael L Hutton

Neurogenetics· March 2014

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A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice.
Ronald B Demattos, Jirong Lu, Ying Tang, Margaret M Racke, Cindy A Delong, Michael L Hutton

Neuron· December 2012

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Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.
Xiyun Chai, Su Wu, Tracey K Murray, Robert Kinley, Claire V Cella, Michael L Hutton

J Biol Chem· September 2011

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Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis.
Jennifer Webster, Eric M Reiman, Victoria L Zismann, Keta D Joshipura, John V Pearson, Michael L Hutton

Int J Mol Epidemiol Genet· July 2011

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Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging.
Zeshan Ahmed, Hong Sheng, Ya-Fei Xu, Wen-Lang Lin, Amy E Innes, Michael L Hutton

Am J Pathol· July 2010

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Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Jason J Corneveaux, Winnie S Liang, Eric M Reiman, Jennifer A Webster, Amanda J Myers, Michael L Hutton

Neurobiol Aging· June 2010

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Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression.
Jason B Tatom, David B Wang, Robert D Dayton, Omar Skalli, Michael L Hutton

Mol Ther· April 2009

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Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia.
Rosa Rademakers, Jason L Eriksen, Matt Baker, Todd Robinson, Zeshan Ahmed, Michael L Hutton

Hum Mol Genet· December 2008

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Early onset familial Alzheimer Disease with spastic paraparesis, dysarthria, and seizures and N135S mutation in PSEN1.
Leslie A Rudzinski, Rita M Fletcher, Dennis W Dickson, Richard Crook, Michael L Hutton

Alzheimer Dis Assoc Disord· November 2008

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Progranulin gene mutation with an unusual clinical and neuropathologic presentation.
Christian Wider, Ryan J Uitti, Zbigniew K Wszolek, John Y Fang, Keith A Josephs, Michael L Hutton

Mov Disord· June 2008

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APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway.
Sigrid B Sando, Stacey Melquist, Ashley Cannon, Michael L Hutton, Olav Sletvold

BMC Neurol· April 2008

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Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment.
Richard J Caselli, Eric M Reiman, Dona E C Locke, Michael L Hutton, Joseph G Hentz

Arch Neurol· September 2007

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GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Eric M Reiman, Jennifer A Webster, Amanda J Myers, John Hardy, Travis Dunckley, Michael L Hutton

Neuron· June 2007

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TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease.
Catalina Amador-Ortiz, Wen-Lang Lin, Zeshan Ahmed, David Personett, Peter Davies, Michael L Hutton

Ann Neurol· May 2007

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Microtubule-associated protein tau as a therapeutic target in neurodegenerative disease.
Hanno M Roder, Michael L Hutton

Expert Opin Ther Targets· April 2007

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Progressive supranuclear palsy: pathology and genetics.
Dennis W Dickson, Rosa Rademakers, Michael L Hutton

Brain Pathol· January 2007

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