Publications by authors named "Michael Landowski"

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Association Between C22:5-Containing Lipids and RPE Pathologies in Mice with Tmem135 Overexpression.
Michael Landowski, Sakae Ikeda, Akihiro Ikeda

Adv Exp Med Biol· May 2025

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Mitochondrial fusion controls the development of specialized mitochondrial structure and metabolism in rod photoreceptor cells.
Michael Landowski, Ryo Hagimori, Purnima Gogoi, Vijesh J Bhute, Sakae Ikeda

bioRxiv· May 2025

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Roles of transmembrane protein 135 in mitochondrial and peroxisomal functions - implications for age-related retinal disease.
Michael Landowski, Purnima Gogoi, Sakae Ikeda, Akihiro Ikeda

Front Ophthalmol (Lausanne)· January 2024

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A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration.
Michael Landowski, Samuel Grindel, Ying Hao, Sakae Ikeda, Catherine Bowes Rickman

J Vis Exp· March 2023

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Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Michael Landowski, Vijesh J Bhute, Samuel Grindel, Zachary Haugstad, Yeboah K Gyening

Commun Biol· January 2023

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Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models.
Michael Landowski, Catherine Bowes Rickman

J Ocul Pharmacol Ther· March 2022

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A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups.
Michael Landowski, Vijesh J Bhute, Tetsuya Takimoto, Samuel Grindel, Pawan K Shahi

Sci Rep· January 2022

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Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice.
Michael Landowski, Samuel Grindel, Pawan K Shahi, Abigail Johnson, Daniel Western

Invest Ophthalmol Vis Sci· October 2020

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High-density lipoproteins are a potential therapeutic target for age-related macular degeneration.
Una L Kelly, Daniel Grigsby, Martha A Cady, Michael Landowski, Nikolai P Skiba

J Biol Chem· September 2020

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Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in Mice.
Erica L Macke, Erika Henningsen, Erik Jessen, Nicholas A Zumwalde, Michael Landowski

Genetics· January 2020

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Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
Michael Landowski, Una Kelly, Mikael Klingeborn, Marybeth Groelle, Jin-Dong Ding

Proc Natl Acad Sci U S A· February 2019

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Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.
Christopher B Toomey, Michael Landowski, Mikael Klingeborn, Una Kelly, John Deans

Invest Ophthalmol Vis Sci· February 2018

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Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.
Jin-Dong Ding, Una Kelly, Michael Landowski, Christopher B Toomey, Marybeth Groelle

Am J Pathol· January 2015

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Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemia.
Michael Landowski, Marie-Françoise O'Donohue, Christopher Buros, Roxanne Ghazvinian, Nathalie Montel-Lehry

Hum Genet· November 2013

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Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome.
Adrianna Vlachos, Jason E Farrar, Eva Atsidaftos, Ellen Muir, Anupama Narla, Michael Landowski

Blood· October 2013

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Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia.
Hanna T Gazda, Milena Preti, Mee Rie Sheen, Marie-Françoise O'Donohue, Adrianna Vlachos, Michael Landowski

Hum Mutat· July 2012

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Expression of the active Notch1 decreases MTC tumor growth in vivo.
Renata Jaskula-Sztul, Pongthep Pisarnturakit, Michael Landowski, Herbert Chen, Muthusamy Kunnimalaiyaan

J Surg Res· November 2011

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The ribosomal basis of Diamond-Blackfan Anemia: mutation and database update.
Ilenia Boria, Emanuela Garelli, Hanna T Gazda, Anna Aspesi, Paola Quarello, Michael Landowski

Hum Mutat· December 2010

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