Publications by authors named "Michael Lerch"

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Is Ultrahigh Dose Rate Critical for the Effectiveness of Microbeam Radiation Therapy in a Broad-Beam Combined Treatment?
Elette Engels, Helen B Forrester, Verdiana Trappetti, Kellie Mouchemore, Mitzi Klein, Michael L F Lerch

Adv Radiat Oncol· February 2026

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The Role of Intrinsically Disordered Domains in Regulating G Protein-Coupled Receptor Signaling.
Jun Xu, Ruoyi Qiu, Alexander M Garces, Harald Hübner, Xinyu Xu, Michael T Lerch

J Am Chem Soc· December 2025

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A procedure for accurate dose measurement in radiotherapy research at millimetre-sized synchrotron beams.
Catharina Mewes, Michael Lerch, Marco Petasecca, Johannes Klingenberg, Guilherme Abreu Faria

Phys Med Biol· November 2025

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Point cloud dosimetry framework for preclinical microbeam radiation therapy.
Jack Humphreys, Christopher White, Florian Mentzel, David Bolst, Jason Paino, Michael Lerch

Phys Med· November 2025

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Radiation Effects in Electret Organic Thin-Film Transistors Due to High Flux and High Dose X-Ray Irradiation.
Alexandria Mitchell, Jessie A Posar, James Cayley, Georgia York, Michael Lerch

Adv Mater· November 2025

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A biased allosteric modulator functions as a molecular glue to induce βAR dimerization.
Brian Kobilka, Jiemin Shen, Teja Peddada, Konstantin Komolov, Francesco De Pascali, Michael Lerch

Res Sq· November 2025

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The Potential of Dosimetry and the Visualization of Microbeam Arrays in NIPAM Gel at the PETRA III Synchrotron.
Thomas Breslin, Malin Kügele, Vincent de Rover, Stefan Fiedler, Tobias Lindner, Michael Lerch

Gels· October 2025

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A biased allosteric modulator functions as a molecular glue to induce βAR dimerization.
Jiemin Shen, Teja Nikhil Peddada, Konstantin E Komolov, Francesco De Pascali, Alexander M Garces, Michael T Lerch

bioRxiv· October 2025

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Playing Hard with Si: Challenges and Opportunities for New Materials in Radiation Therapy Dosimetry.
James Cayley, Ilia Filipev, Jeremy A Davis, Vincent de Rover, Dean Cutajar, Michael L F Lerch

Adv Mater· September 2025

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A canine head phantom for quality assurance in multiport microbeam radiation therapy: animal phantom fabrication and dosimetry protocol.
John Paul O Bustillo, Vincent de Rover, Elette E M Engels, James Cayley, Matthew Cameron, Michael L F Lerch

Biomed Phys Eng Express· September 2025

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The role of intrinsically disordered domains in regulating G protein coupled receptor signaling.
Jun Xu, Ruoyi Qiu, Alexander M Garces, Harald Hübner, Xinyu Xu, Michael T Lerch

bioRxiv· September 2025

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Capturing protein dynamics across timescales with site-directed spin labeling electron paramagnetic resonance spectroscopy.
Patrick C Brennan, Julian D Grosskopf, Alexander M Garces, Cassandra L Trier, Michael T Lerch

Curr Opin Struct Biol· August 2025

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Comparison of Deep Learning Models for fast and accurate dose map prediction in Microbeam Radiation Therapy.
Lorenzo Arsini, Jack Humphreys, Christopher White, Florian Mentzel, Jason Paino, Michael Lerch

Phys Med· August 2025

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Treatment planning for in vivo multi-fraction, multi-port, multi-modal Synchrotron Radiotherapy.
Micah J Barnes, Matthew Cameron, Elette Engels, Mitzi Klein, Cristian Fernandez-Palomo, Michael Lerch

Phys Med· August 2025

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A high-sensitivity stopped-flow EPR system to monitor millisecond conformational kinetics in spin-labeled proteins.
Alexander M Garces, Richard R Mett, Candice S Klug, Jason W Sidabras, Michael T Lerch

Protein Sci· August 2025

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Comparison of LEM and MKM based RBE-weighted doses from microdosimetric measurements with silicon 3D microdosimeter.
Emanuele Maria Data, James Vohradsky, Benjamin James, Vladimir Pan, David Bolst, Michael Lerch

Phys Med· August 2025

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Fast and Fractionated: Correlation of Dose Attenuation and the Response of Human Cancer Cells in a New Anthropomorphic Brain Phantom.
Bernd Frerker, Elette Engels, Jason Paino, Vincent de Rover, John Paul Bustillo, Michael Lerch

Biomimetics (Basel)· July 2025

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Improved EPR sensitivity for aqueous biological samples using low-volume multi-channel cells and dielectric resonators.
Richard R Mett, Alexander M Garces, Anand Anilkumar, Joseph T Wehrley, Michael T Lerch

bioRxiv· June 2025

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ProGuide: a flexible framework for modeling global conformational rearrangements in proteins using DEER-derived distance restraints.
Julian D Grosskopf, Peter Kasson, Michael T Lerch

bioRxiv· June 2025

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The inhibition of photocatalytic activity of rutile nanoparticles surface encrustation with La(OH) quantum dots.
Nuwangi P Cooray, Rajib Chandra Das, Philip J Barker, Michael Lerch, Jung Ho Kim

J Mater Chem B· May 2025

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Combinational Radiotherapies Improve Brain Cancer Treatment at High Dose Rates In Vitro.
Michael Valceski, Elette Engels, Sarah Vogel, Jason Paino, Dylan Potter, Michael Lerch

Cancers (Basel)· May 2025

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Three-dimensional bioprinted in vitro glioma tumor constructs for synchrotron microbeam radiotherapy dosimetry and biological study using gelatin methacryloyl hydrogel.
John Paul O Bustillo, Elette E M Engels, Vincent de Rover, Kiarn Roughley, Julia Rebecca D Posadas, Michael L F Lerch

Sci Rep· April 2025

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Quantum-Dot Ceramic Composites for Oxidative Stress Mitigation under Broad-Spectrum Radiation Exposure.
Rajib Chandra Das, Marcela L Chaki Borrás, Jung Ho Kim, Martin Carolan, Ronald Sluyter, Michael Lerch

ACS Appl Mater Interfaces· March 2025

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Structure and dynamics determine G protein coupling specificity at a class A GPCR.
Marina Casiraghi, Haoqing Wang, Patrick C Brennan, Chris Habrian, Harald Hübner, Michael T Lerch

Sci Adv· March 2025

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A High-Sensitivity Stopped-Flow EPR System to Monitor Millisecond Conformational Kinetics in Spin-Labeled Proteins.
Alexander M Garces, Richard R Mett, Candice S Klug, Jason W Sidabras, Michael T Lerch

bioRxiv· March 2025

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