Publications by authors named "Michael Lockyer"

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Crystallographic and microcalorimetric analyses reveal the structural basis for high arginine specificity in the Salmonella enterica serovar Typhimurium periplasmic binding protein STM4351.
Anna L Stamp, Paul Owen, Kamel El Omari, Michael Lockyer, Heather K Lamb

Proteins· July 2011

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Structural and functional characterization of Salmonella enterica serovar Typhimurium YcbL: an unusual Type II glyoxalase.
Anna L Stamp, Paul Owen, Kamel El Omari, Charles E Nichols, Michael Lockyer

Protein Sci· October 2010

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Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH).
Roy R Chaudhuri, Andrew G Allen, Paul J Owen, Gil Shalom, Karl Stone, Michael Lockyer

BMC Genomics· July 2009

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Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium.
Heather K Lamb, Paul Thompson, Catherine Elliott, Ian G Charles, Jamie Richards, Michael Lockyer

Protein Sci· November 2007

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RSV604, a novel inhibitor of respiratory syncytial virus replication.
Joanna Chapman, Elizabeth Abbott, Dagmar G Alber, Robert C Baxter, Sian K Bithell, Michael J Lockyer

Antimicrob Agents Chemother· September 2007

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Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine.
Masayo Kotaka, Jingshan Ren, Michael Lockyer, Alastair R Hawkins, David K Stammers

J Biol Chem· October 2006

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Structure of Staphylococcus aureus guanylate monophosphate kinase.
Kamel El Omari, Balvinder Dhaliwal, Michael Lockyer, Ian Charles, Alastair R Hawkins

Acta Crystallogr Sect F Struct Biol Cryst Commun· October 2006

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Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate.
Balvinder Dhaliwal, Jingshan Ren, Michael Lockyer, Ian Charles, Alastair R Hawkins

Acta Crystallogr Sect F Struct Biol Cryst Commun· August 2006

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Structures of S. aureus thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding.
Masayo Kotaka, Balvinder Dhaliwal, Jingshan Ren, Charles E Nichols, Richard Angell, Michael Lockyer

Protein Sci· April 2006

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1,4-Benzodiazepines as inhibitors of respiratory syncytial virus.
Malcolm C Carter, Dagmar G Alber, Robert C Baxter, Sian K Bithell, Jo Budworth, Michael J Lockyer

J Med Chem· April 2006

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GTP cyclohydrolase II structure and mechanism.
Jingshan Ren, Masayo Kotaka, Michael Lockyer, Heather K Lamb, Alastair R Hawkins

J Biol Chem· November 2005

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Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase.
Balvinder Dhaliwal, Charles E Nichols, Jingshan Ren, Michael Lockyer, Ian Charles

FEBS Lett· September 2004

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