Publications by authors named "Michael Lutteropp"

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An Innovative Approach to Optimize First-In-Human Minimal Anticipated Biological Effect Level Based Starting Dose in Oncology Trials for Bispecific T-Cell Engagers: Experience from A Solid Tumor Bispecific T-Cell Engager.
Di Zhou, Roman Kischel, Sabine Stienen, Danielle Townsley, Alexander Sternjak, Michael Lutteropp

Clin Pharmacol Ther· January 2025

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Preclinical Assessment of a MUC12-Targeted BiTE (Bispecific T-cell Engager) Molecule.
Elizabeth Pham, Matthias Friedrich, Famke Aeffner, Michael Lutteropp, Natalie F Mariano

Mol Cancer Ther· October 2021

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CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells.
Regina Jitschin, Domenica Saul, Martina Braun, Sehmus Tohumeken, Simon Völkl, Michael Lutteropp

J Immunother Cancer· November 2018

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Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option.
Hauke Stamm, Felix Klingler, Eva-Maria Grossjohann, Jana Muschhammer, Eik Vettorazzi, Michael Lutteropp

Oncogene· September 2018

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Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.
Tiago C Luis, Sidinh Luc, Takuo Mizukami, Hanane Boukarabila, Supat Thongjuea, Michael Lutteropp

Nat Immunol· December 2016

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Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.
Roy Drissen, Natalija Buza-Vidas, Petter Woll, Supat Thongjuea, Adriana Gambardella, Michael Lutteropp

Nat Immunol· June 2016

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Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.
Charlotta Böiers, Joana Carrelha, Michael Lutteropp, Sidinh Luc, Joanna C A Green

Cell Stem Cell· November 2013

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Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
Alejandra Sanjuan-Pla, Iain C Macaulay, Christina T Jensen, Petter S Woll, Tiago C Luis, Michael Lutteropp

Nature· October 2013

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FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
Adam J Mead, Shabnam Kharazi, Deborah Atkinson, Iain Macaulay, Christian Pecquet, Michael Lutteropp

Cell Rep· June 2013

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Dicer is selectively important for the earliest stages of erythroid development.
Natalija Buza-Vidas, Valeriu B Cismasiu, Susan Moore, Adam J Mead, Petter S Woll, Michael Lutteropp

Blood· September 2012

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The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
Sidinh Luc, Tiago C Luis, Hanane Boukarabila, Iain C Macaulay, Natalija Buza-Vidas, Michael Lutteropp

Nat Immunol· February 2012

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FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
Natalija Buza-Vidas, Petter Woll, Anne Hultquist, Sara Duarte, Michael Lutteropp

Blood· August 2011

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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Monika Mortensen, Elizabeth J Soilleux, Gordana Djordjevic, Rebecca Tripp, Michael Lutteropp

J Exp Med· March 2011

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