Publications by authors named "Michael McCullar"

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Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors.
Yong Xu, Benjamin G Brenning, Steven G Kultgen, Jason M Foulks, Adrianne Clifford, Michael V McCullar

ACS Med Chem Lett· January 2015

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A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas.
Jason M Foulks, Kent J Carpenter, Bai Luo, Yong Xu, Anna Senina, Michael V McCullar

Neoplasia· May 2014

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Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2).
Yong Xu, Xiao-Hui Liu, Michael Saunders, Scott Pearce, Jason M Foulks, Michael V McCullar

Bioorg Med Chem Lett· January 2014

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Discovery of Novel Putative Inhibitors of UDP-GlcNAc 2-Epimerase as Potent Antibacterial Agents.
Yong Xu, Benjamin Brenning, Adrianne Clifford, David Vollmer, Jared Bearss, Michael V McCullar

ACS Med Chem Lett· December 2013

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Pharmacologic activation of PKM2 slows lung tumor xenograft growth.
K Mark Parnell, Jason M Foulks, Rebecca N Nix, Adrianne Clifford, Jeremy Bullough, Michael V McCullar

Mol Cancer Ther· August 2013

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Synthesis and structure-activity relationship of 2-arylamino-4-aryl-pyrimidines as potent PAK1 inhibitors.
Yong Xu, Jason M Foulks, Adrianne Clifford, Benjamin Brenning, Shuping Lai, Michael V McCullar

Bioorg Med Chem Lett· July 2013

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Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Koc-Kan Ho, K Mark Parnell, Yi Yuan, Yong Xu, Steven G Kultgen, Michael V McCullar

Bioorg Med Chem Lett· January 2013

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Epigenetic drug discovery: targeting DNA methyltransferases.
Jason M Foulks, K Mark Parnell, Rebecca N Nix, Suzanna Chau, Krzysztof Swierczek, Michael V McCullar

J Biomol Screen· January 2012

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Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies.
John Lyons, Emel Bayar, Gil Fine, Michael McCullar, Randee Rolens

Curr Opin Investig Drugs· December 2003

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