Publications by authors named "Michael Michaelides"

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The Neuroscience of Drug Reward and Addiction.
Nora D Volkow, Michael Michaelides, Ruben Baler

Physiol Rev· October 2019

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Bifunctional modulation of NMDA and opioid receptors in ketamine reinforcement and misuse: implications for substance use disorder treatment.
Marjorie R Levinstein, Ingrid Schoenborn, Peter Manza, Alan F Schatzberg, Carlos A Zarate, Michael Michaelides

Biol Psychiatry· December 2025

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The role of central versus peripheral opioid receptors in fentanyl-induced brain hypoxia.
Eugene A Kiyatkin, Feonil G Limiac, Michael R Noya, Juan L Gomez, Michael Michaelides

J Neurophysiol· December 2025

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Early life adversity increases striatal dopamine D1 receptor density and promotes social alcohol drinking in mice, especially males.
Lucy G Anderson, Anna Tischer, Roland Bock, Michael Michaelides, Veronica A Alvarez

bioRxiv· November 2025

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A reversible allosteric inhibitor of GlyT2 alleviates neuropathic pain without on-target side effects.
Ryan P Cantwell Chater, Julian Peiser-Oliver, Tanmay K Pati, Ada S Quinn, Irina Lotsaris, Michael Michaelides

bioRxiv· November 2025

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Cocaine chemogenetics blunts drug-seeking by synthetic physiology.
Juan L Gomez, Christopher J Magnus, Jordi Bonaventura, Oscar Solis, Fallon P Curry, Michael Michaelides

Nature· October 2025

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Misleading Labeling of S-Methadone as a Novel N-Methyl-D-Aspartate Receptor Antagonist.
Sergi Ferré, Michael Michaelides

J Clin Psychiatry· September 2025

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The dopaminergic effects of esketamine are mediated by a dual mechanism involving glutamate and opioid receptors.
Arianna Rizzo, Maria Zelai Garçon-Poca, Amelie Essmann, Adriana Jesus Souza, Michael Michaelides

Mol Psychiatry· August 2025

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A putative binding model of nitazene derivatives at the μ-opioid receptor.
Joseph Clayton, Lei Shi, Michael J Robertson, Georgios Skiniotis, Michael Michaelides

Neuropharmacology· August 2025

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Locomotor activity depends on β-arrestin recruitment by the dopamine D receptor in the striatal D-D receptor heteromer.
Alexandra H Evans, Marc Ciruela-Jardí, William Rea, Bradley M Keegan, Marjorie R Levinstein, Michael Michaelides

Pharmacol Res· August 2025

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Sigma-1 Receptor Promotes Glycolysis in Neuronal Systems by Suppressing GRIM19.
Simon Couly, Yuko Yasui, Ioannis Grammatikakis, Yuriko Kimura, Josh Hinkle, Michael Michaelides

bioRxiv· July 2025

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Frontostriatal regulation of brain circuits contributes to flexible decision making.
Ying Duan, Zilu Ma, Pei-Jung Tsai, Hanbing Lu, Xiang Xiao, Michael Michaelides

Neuropsychopharmacology· June 2025

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Reply to "Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the μ-opioid receptor ligand (S)-methadone'".
Marjorie R Levinstein, Paulo A De Oliveira, Nil Casajuana-Martin, Cesar Quiroz, Reece C Budinich, Michael Michaelides

Mol Psychiatry· April 2025

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Redefining Ketamine Pharmacology for Antidepressant Action: Synergistic NMDA and Opioid Receptor Interactions?
Marjorie R Levinstein, Reece C Budinich, Jordi Bonaventura, Alan F Schatzberg, Carlos A Zarate, Michael Michaelides

Am J Psychiatry· March 2025

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A Putative Binding Model of Nitazene Derivatives at the -Opioid Receptor.
Joseph Clayton, Lei Shi, Michael J Robertson, Georgios Skiniotis, Michael Michaelides

bioRxiv· February 2025

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Repetitive Grooming Behavior Following Aversive Stimulus Coincides with a Decrease in Anterior Hypothalamic Area Activity.
Brenton T Laing, Megan S Anderson, Aishwarya Jayan, Anika S Park, Lydia J Erbaugh, Michael Michaelides

eNeuro· January 2025

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Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor.
Yiyun Yu, Miyeon Jang, Julie Miyashiro, Richard F Clark, Gui-Dong Zhu, Michael R Michaelides

J Med Chem· October 2024

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Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with Target Engagement.
Robin R Frey, Navendu Jana, Jacob V Gorman, Jin Wang, Heath A Smith, Michael R Michaelides

J Med Chem· October 2024

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Preexisting risk-avoidance and enhanced alcohol relief are driven by imbalance of the striatal dopamine receptors in mice.
Miriam E Bocarsly, Marlisa J Shaw, Emilya Ventriglia, Lucy G Anderson, Hannah C Goldbach, Michael Michaelides

Nat Commun· October 2024

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Evaluation of [F]fluoroestradiol and ChRERα as a gene expression PET reporter system in rhesus monkey brain.
Bing Li, Palak Wadhwa, Walter Lerchner, Paolo Zanotti-Fregonara, Jeih-San Liow, Michael Michaelides

Mol Ther· July 2024

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Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet.
András H Lékó, Adriana Gregory-Flores, Renata C N Marchette, Juan L Gomez, Janaina C M Vendruscolo, Michael Michaelides

Commun Biol· May 2024

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Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone.
Marjorie R Levinstein, Paulo A De Oliveira, Nil Casajuana-Martin, Cesar Quiroz, Reece C Budinich, Michael Michaelides

Mol Psychiatry· March 2024

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Synthesis and preclinical evaluation of [C]uPSEM792 for PSAM-GlyR based chemogenetics.
Sridhar Goud Nerella, Sanjay Telu, Jeih-San Liow, Madeline D Jenkins, Sami S Zoghbi, Michael Michaelides

Sci Rep· January 2024

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Sex dependence of opioid-mediated responses to subanesthetic ketamine in rats.
Tommaso Di Ianni, Sedona N Ewbank, Marjorie R Levinstein, Matine M Azadian, Reece C Budinich, Michael Michaelides

Nat Commun· January 2024

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Enabling, Decagram-Scale Synthesis of Macrocyclic MCL-1 Inhibitor ABBV-467.
Patrick B Brady, Bryan K Sorensen, Roberto M Risi, Michael L Curtin, Robert A Mantei, Michael R Michaelides

J Org Chem· November 2023

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DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates.
Sascha A L Mueller, Jonathan A Oler, Patrick H Roseboom, Nakul Aggarwal, Margaux M Kenwood, Michael Michaelides

Curr Res Neurobiol· October 2023

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