PubHawk
Physiol Rev October 2019 PMID 31507244

The Neuroscience of Drug Reward and Addiction.

Nora D Volkow, Michael Michaelides, Ruben Baler

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Mentions

44
Peak: 9 in Sep 2019
across 4 sources since Sep 2019

Extended reach

560,802
potential audience

Total likes

21,008

Video views

522,731

Mentions per month

Sep 2019 – Dec 2025

Where it's discussed

  • X / Twitter28 posts
  • YouTube9 videos
  • News5 articles
  • Facebook2 posts

AI synopsis

What people are saying

Discussions reflect a strong agreement with the scientific focus of the publication, with posts praising the importance of neurobiological explanations and citing research papers; the tone shows enthusiasm and curiosity, especially when referencing new reviews and studies, which underlines the perceived relevance and impact of this scientific work.

AgreementModerate agreement

Most posts acknowledge and support the scientific findings, emphasizing the importance of neuroscience in understanding addiction.

InterestHigh interest

The discussions are highly focused on neurobiological details and implications, showing strong curiosity and relevance for those interested in science and addiction.

EngagementModerate engagement

Posts include references to recent research, sharing links and commentary, demonstrating active engagement and consideration of the article's content.

ImpactModerate impact

The discourse highlights the significance of neuroscience research for understanding addiction, with mentions of advances in therapy and scientific validation, indicating meaningful influence.

Abstract in brief

  • The reward and addiction cycle in the brain is primarily driven by dopamine signaling in areas like the nucleus accumbens, and chronic drug use causes neuroadaptations in brain regions responsible for decision making, memory, and emotion, which can lead to addiction.
  • Negative emotional states caused by changes in the amygdala and other limbic pathways can motivate ongoing drug use, even as the brain's response to drugs becomes less rewarding, leading to a cycle of craving and consumption.
  • Addiction involves a disrupted balance between increased drug cues triggering dopamine release, and a weakened prefrontal cortex that reduces self-control, making compulsive drug-taking more likely; future treatments aim to reverse these neuroadaptations.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Rei Akaishi
@rei_akaishi · X

The Neuroscience of Drug Reward and Addiction https://t.co/VKBb3ABfu9

Sep 17, 2019 · 8 likes · 1 share · 2,858 followers View post →
Will Lawn
@Will_Lawn · X

This diagram in Volkow's new review demonstrates the extreme reductivism present in addiction neuroscience research. Do neuroadaptations, such as increased dendritic spine density, really cause addiction? Might there be other things going on!? https://t.co/3pORB9ygsS https://t.co/HjUfVsuCDs

Sep 20, 2019 · 6 likes · 1,190 followers View post →
APS Publications
@APSPublications · X

The #Neuroscience of #Drug Reward and #Addiction - new review article in @physiolrev #dopamine #opioids #cannabis https://t.co/cbgXhGeNkL https://t.co/HrWEn16Qlj

Sep 13, 2019 · 5 likes · 2 shares · 7,349 followers View post →
Maria Nalberczak-Skora
@brabuska · X

Nora Volkow just cited my paper! Yay! :) 10.1152/physrev.00014.2018

Oct 3, 2019 · 3 likes · 80 followers View post →
Physiological Reviews
@physiolrev · X

In our October includes an update of The Neuroscience of Drug Reward and Addiction, summarizing a very broad range of addiction research with regard to human studies, genetics and novel therapeutic strategies. https://t.co/TxXCHhvk2g #Physiology #Addiction #Drug #neuroscience https://t.co/wMPkaG7ypx

Sep 16, 2019 · 2 likes · 2 shares · 5,236 followers View post →
McGuffin
@GuffyNicola · X

@ClarkeMicah @HockleyToby I know Dr.Hitchens doesn’t believe in neuroscience either but others may find this interesting. https://t.co/oHrVbRBhEe

May 14, 2021 · 1 like · 2,324 followers View post →

All mentions

@tiagodeathayde@mastodon.social
@tiagodeathayde · X

@mariguilherme e Andrei Mayer no youtube, especialmente este episódio https://t.co/7q9HOSUUoQ

Feb 23, 2024 · 1 like · 292 followers View post →
Douglas
@douglasbhaber · X

VÍCIOS: Tratamento e Diagnóstico (álcool, drogas, celular e outros) https://t.co/ngkTc8py6l

Aug 10, 2023 · 3,083 followers View post →
@tiagodeathayde@mastodon.social
@tiagodeathayde · X

VÍCIOS: Tratamento e Diagnóstico (álcool, drogas, celular e outros) https://t.co/7q9HOSUUoQ

Aug 6, 2023 · 292 followers View post →
Bola de Fogo
@masolzs · X

Vício em celular e dormir https://t.co/OIV7ktUznM

Aug 2, 2023 · 432 followers View post →
Tina Trautmann
@tina_trautmann · X

@TimSodermanns @Shadowrush1 @tagesschau Für die meisten ist Cannabis sicher keine Lösung für gesundheitliche Probleme. https://t.co/0yqZaIfqRc

Apr 13, 2023 · 1,770 followers View post →
Tina Trautmann
@tina_trautmann · X

@MadDiasYoung1 @tagesschau Der Begriff „Prohibition“ ist ja völlig falsch gewählt in diesem Zusammenhang. Aber das wird Dich eh nicht interessieren. Guck Dir mal das Video an und dann nenne mir mal einen Grund, weshalb noch weitere Drogen legalisiert werden sollten. https://t.co/0yqZaIfqRc

Apr 13, 2023 · 1,770 followers View post →
Juan Ignacio Gil-Hutton
@jgilhutton · X

https://t.co/eRYqWDFuhj

Apr 6, 2023 · 314 followers View post →
Dylan
@UtdDxIan · X

@daboftruth @big939793 @tahhlorrdmade @FollowMy_Dreams They’re just some of the factors that make you more likely to be addicted, but you also have to look into the neuroscience of addiction. Addiction is pretty much a chronic “disease” of the brain by fucking up the way your brain uses dopamine, have a read: https://t.co/bjBQqMjDme

Feb 14, 2022 · 177 followers View post →
RS
@Rye_Sullivan_ · X

@ClarkeMicah Some useful reading that I can fit in one tweet - demonstrating that addiction is a proven neurological condition: https://t.co/Wn1vYNW5vc https://t.co/wCJMdANVnB https://t.co/bKBxb2eWMw https://t.co/P6eojRPckB

Jan 3, 2022 · 266 followers View post →
BeyondStigma
@BeyondStigma · X

RT @JosephHay92: @CuckSwarm @nanimator @AndrewBrookLdn @LinManuelRwanda @doukhobour @ClarkeMicah Oh look, more scientific literature on the…

Dec 6, 2021 · 1 share · 807 followers View post →
Joe Cicero
@JosephHay92 · X

@CuckSwarm @nanimator @AndrewBrookLdn @LinManuelRwanda @doukhobour @ClarkeMicah Oh look, more scientific literature on the link between neuroscience and addiction.... I could go all day long with these papers, it is after all, been heavily researched... https://t.co/cuVVMZDkwC

Dec 6, 2021 · 1 like · 1 share · 190 followers View post →
Demone Razionale
@DemoneRazionale · X

@TheQueerFae @nojussoli @fabiomonac @MadameA02 Evidentemente ti sfuggono gli ultimi 50 anni di neurofisiologia e psicopatologia. Per non parlare della giurisprudenza, che Rotari era più avanti di te. https://t.co/5DC5mAAwqw E fattela una corsetta ogni tanto, che sennò poi aumenti i fattori di rischio.

Jul 14, 2021 · 54 followers View post →
McGuffin
@GuffyNicola · X

@ClarkeMicah @HockleyToby I know Dr.Hitchens doesn’t believe in neuroscience either but others may find this interesting. https://t.co/oHrVbRBhEe

May 14, 2021 · 1 like · 2,324 followers View post →
Mary, Mary quite contrary
@Sea_hag_ · X

https://t.co/jdcskJwMxC

Apr 8, 2021 · 543 followers View post →
Mary, Mary quite contrary
@Sea_hag_ · X

@marshallcsp @EnricoPallazo5 @countdowntoFI @FitFounder Enrico is apparently not educated in neuroscience. Such is Twitter. https://t.co/jdcskJwMxC https://t.co/ApeZtoB1KG

Apr 8, 2021 · 543 followers View post →
Ancyborov Andrei
@ancyborov · X

RT @Neuro_psych: The Neuroscience of Drug Reward and Addiction by Nora D. Volkow, Michael Michaelides, and Ruben Baler Physiological Review…

Oct 17, 2019 · 1 share · 28 followers View post →
Anton Pashkov
@anton_pashkov03 · X

The Neuroscience of Drug Reward and Addiction by Nora D. Volkow, Michael Michaelides, and Ruben Baler Physiological Reviews| Latest issue https://t.co/PwLYprt6I2 https://t.co/hiIgen7tpK

Oct 17, 2019 · 1 like · 1 share · 1,680 followers View post →
Frank Ryan
@drfnryan · X

Yet to read full txt, but this looks interesting. The Neuroscience of Drug Reward and Addiction | Physiological Reviews https://t.co/M4hahhqVCk

Oct 8, 2019 · 1 like · 264 followers View post →
Maria Nalberczak-Skora
@brabuska · X

Nora Volkow just cited my paper! Yay! :) 10.1152/physrev.00014.2018

Oct 3, 2019 · 3 likes · 80 followers View post →
BiNE Network
@BineNetwork · X

RT @physiolrev: In our October includes an update of The Neuroscience of Drug Reward and Addiction, summarizing a very broad range of addic…

Sep 26, 2019 · 2 shares · 161 followers View post →
Dr. Laura Ginesi
@laura_ginesi · X

RT @physiolrev: In our October includes an update of The Neuroscience of Drug Reward and Addiction, summarizing a very broad range of addic…

Sep 25, 2019 · 2 shares · 561 followers View post →
Will Lawn
@Will_Lawn · X

This diagram in Volkow's new review demonstrates the extreme reductivism present in addiction neuroscience research. Do neuroadaptations, such as increased dendritic spine density, really cause addiction? Might there be other things going on!? https://t.co/3pORB9ygsS https://t.co/HjUfVsuCDs

Sep 20, 2019 · 6 likes · 1,190 followers View post →
David V. Smith (@dvsmith.bsky.social)
@DVSneuro · X

RT @rei_akaishi: The Neuroscience of Drug Reward and Addiction https://t.co/VKBb3ABfu9

Sep 17, 2019 · 1 share · 1,542 followers View post →
Rei Akaishi
@rei_akaishi · X

The Neuroscience of Drug Reward and Addiction https://t.co/VKBb3ABfu9

Sep 17, 2019 · 8 likes · 1 share · 2,858 followers View post →
Physiological Reviews
@physiolrev · X

In our October includes an update of The Neuroscience of Drug Reward and Addiction, summarizing a very broad range of addiction research with regard to human studies, genetics and novel therapeutic strategies. https://t.co/TxXCHhvk2g #Physiology #Addiction #Drug #neuroscience https://t.co/wMPkaG7ypx

Sep 16, 2019 · 2 likes · 2 shares · 5,236 followers View post →
AJP-Endocrinology and Metabolism
@AJPEndoMetab · X

RT @APSPublications: The #Neuroscience of #Drug Reward and #Addiction - new review article in @physiolrev #dopamine #opioids #cannabis htt…

Sep 14, 2019 · 2 shares · 2,653 followers View post →
Andrés A. Ponce M.D., Ph.D.
@aponce · X

RT @APSPublications: The #Neuroscience of #Drug Reward and #Addiction - new review article in @physiolrev #dopamine #opioids #cannabis htt…

Sep 13, 2019 · 2 shares · 1,580 followers View post →
APS Publications
@APSPublications · X

The #Neuroscience of #Drug Reward and #Addiction - new review article in @physiolrev #dopamine #opioids #cannabis https://t.co/cbgXhGeNkL https://t.co/HrWEn16Qlj

Sep 13, 2019 · 5 likes · 2 shares · 7,349 followers View post →