Publications by authors named "Michael Ominsky"

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Once-Weekly Navepegritide in Children With Achondroplasia: The APPROACH Randomized Clinical Trial.
Ravi Savarirayan, Ciara McDonnell, Carlos A Bacino, Daniel G Hoernschemeyer, Janet M Legare, Michael S Ominsky

JAMA Pediatr· November 2025

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High-dose romosozumab promoted bone regeneration of critical-size ulnar defect filled with demineralized bone matrix in nonhuman primates.
Xiaodong Li, Frank Asuncion, Michael Ominsky, Qing-Tian Niu, Kristina E Akesson

J Orthop Translat· September 2025

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Setrusumab for the treatment of osteogenesis imperfecta: 12-month results from the phase 2b asteroid study.
Francis H Glorieux, Bente Langdahl, Roland Chapurlat, Suzanne Jan De Beur, Vernon Reid Sutton, Michael S Ominsky

J Bone Miner Res· September 2024

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Palopegteriparatide Treatment Improves Renal Function in Adults with Chronic Hypoparathyroidism: 1-Year Results from the Phase 3 PaTHway Trial.
Lars Rejnmark, Elvira O Gosmanova, Aliya A Khan, Noriko Makita, Yasuo Imanishi, Michael S Ominsky

Adv Ther· June 2024

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Dual Inhibition of the Wnt Inhibitors DKK1 and Sclerostin Promotes Fracture Healing and Increases the Density and Strength of Uninjured Bone: An Experimental Study in Nonhuman Primates.
Monica Florio, Paul J Kostenuik, Marina Stolina, Franklin J Asuncion, Mario Grisanti, Michael S Ominsky

J Bone Joint Surg Am· August 2023

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Gender-Related Impact of Sclerostin Antibody on Bone in the Osteogenesis Imperfecta Mouse.
Mickaël Cardinal, Antoine Chretien, Thomas Roels, Sébastien Lafont, Michael S Ominsky

Front Genet· August 2021

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Early Effects of Abaloparatide on Bone Formation and Resorption Indices in Postmenopausal Women With Osteoporosis.
David W Dempster, Hua Zhou, Sudhaker D Rao, Chris Recknor, Paul D Miller, Michael S Ominsky

J Bone Miner Res· April 2021

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Effects of systemically administered abaloparatide, an osteoanabolic PTHrP analog, as an adjuvant therapy for spinal fusion in rats.
Heike Arlt, Tatiana Besschetnova, Michael S Ominsky, Douglas C Fredericks, Beate Lanske

JOR Spine· March 2021

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Effects of abaloparatide and teriparatide on bone resorption and bone formation in female mice.
Heike Arlt, Tara Mullarkey, Dorothy Hu, Roland Baron, Michael S Ominsky

Bone Rep· December 2020

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Sclerostin-Antibody Treatment Decreases Fracture Rates in Axial Skeleton and Improves the Skeletal Phenotype in Growing oim/oim Mice.
Mickaël Cardinal, Alicia Dessain, Thomas Roels, Sébastien Lafont, Michael S Ominsky

Calcif Tissue Int· May 2020

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Sclerostin antibody reduces long bone fractures in the oim/oim model of osteogenesis imperfecta.
Mickaël Cardinal, Janne Tys, Thomas Roels, Sébastien Lafont, Michael S Ominsky

Bone· July 2019

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Abaloparatide improves cortical geometry and trabecular microarchitecture and increases vertebral and femoral neck strength in a rat model of male osteoporosis.
Tatiana Besschetnova, Daniel J Brooks, Dorothy Hu, Kenichi Nagano, Jordan Nustad, Michael Ominsky

Bone· July 2019

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Abaloparatide, a PTH receptor agonist with homology to PTHrP, enhances callus bridging and biomechanical properties in rats with femoral fracture.
Beate Lanske, Heidi Chandler, Allen Pierce, Jeffery Brown, Michael Ominsky

J Orthop Res· April 2019

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Abaloparatide, a novel osteoanabolic PTHrP analog, increases cortical and trabecular bone mass and architecture in orchiectomized rats by increasing bone formation without increasing bone resorption.
Heidi Chandler, Beate Lanske, Aurore Varela, Martin Guillot, Marilyne Boyer, Michael Ominsky

Bone· March 2019

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Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury.
Wei Zhao, Xiaodong Li, Yuanzhen Peng, Yiwen Qin, Jiangping Pan, Michael S Ominsky

Calcif Tissue Int· October 2018

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Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody.
Rogely Waite Boyce, Danielle Brown, Melanie Felx, Nacera Mellal, Kathrin Locher, Michael S Ominsky

Bone Rep· June 2018

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Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats.
Scott Taylor, Rong Hu, Efrain Pacheco, Kathrin Locher, Ian Pyrah, Michael S Ominsky

Bone Rep· June 2018

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Sclerostin Antibody Reverses Bone Loss by Increasing Bone Formation and Decreasing Bone Resorption in a Rat Model of Male Osteoporosis.
Xiaodong Li, Michael S Ominsky, Kelly S Villasenor, Qing-Tian Niu, Frank J Asuncion

Endocrinology· January 2018

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Etelcalcetide (AMG 416), a peptide agonist of the calcium-sensing receptor, preserved cortical bone structure and bone strength in subtotal nephrectomized rats with established secondary hyperparathyroidism.
Xiaodong Li, Longchuan Yu, Frank Asuncion, Mario Grisanti, Shawn Alexander, Michael S Ominsky

Bone· December 2017

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Sclerostin Blockade and Zoledronic Acid Improve Bone Mass and Strength in Male Mice With Exogenous Hyperthyroidism.
Elena Tsourdi, Franziska Lademann, Michael S Ominsky, Eddy Rijntjes, Josef Köhrle

Endocrinology· November 2017

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Kinetic reconstruction reveals time-dependent effects of romosozumab on bone formation and osteoblast function in vertebral cancellous and cortical bone in cynomolgus monkeys.
Rogely Waite Boyce, Qing-Tian Niu, Michael S Ominsky

Bone· August 2017

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Romosozumab Treatment Converts Trabecular Rods into Trabecular Plates in Male Cynomolgus Monkeys.
Jonathan B Matheny, Ashley M Torres, Michael S Ominsky, Christopher J Hernandez

Calcif Tissue Int· July 2017

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Comparing the incidence of bone tumors in rats chronically exposed to the selective PTH type 1 receptor agonist abaloparatide or PTH(1-34).
Jacquelin Jolette, Bassem Attalla, Aurore Varela, Gerald G Long, Nacera Mellal, Michael S Ominsky

Regul Toxicol Pharmacol· June 2017

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Sclerostin Antibody Treatment Enhances Rotator Cuff Tendon-to-Bone Healing in an Animal Model.
Shivam A Shah, Ioannis Kormpakis, Necat Havlioglu, Michael S Ominsky, Leesa M Galatz

J Bone Joint Surg Am· May 2017

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Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys.
Michael S Ominsky, Steven K Boyd, Aurore Varela, Jacquelin Jolette, Melanie Felx

J Bone Miner Res· April 2017

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