Publications by authors named "Michael Pieper"

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SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance.
Ali Mroueh, Paola Algara-Suarez, Walaa Fakih, Dal-Seong Gong, Kensuke Matsushita, Michael Paul Pieper

Cardiovasc Res· May 2025

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A novel soluble guanylate cyclase activator, avenciguat, in combination with empagliflozin, protects against renal and hepatic injury in diabetic mice.
Nisha Sharma, Wenjin Liu, Xiao-Qing E Tsai, Zhou Wang, Connor Outtrim, Michael P Pieper

Am J Physiol Endocrinol Metab· March 2025

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Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage.
Panagiota Efstathia Nikolaou, Lara S F Konijnenberg, Ioannis V Kostopoulos, Marios Miliotis, Nikolaos Mylonas, Michael Paul Pieper

JACC Basic Transl Sci· January 2025

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Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2.
Sha Chen, Qian Wang, Diane Bakker, Xin Hu, Liping Zhang, Michael P Pieper

Basic Res Cardiol· October 2024

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Activated factor X stimulates atrial endothelial cells and tissues to promote remodelling responses through AT1R/NADPH oxidases/SGLT1/2.
Walaa Fakih, Ali Mroueh, Dal-Seong Gong, Shinnosuke Kikuchi, Michael Paul Pieper

Cardiovasc Res· September 2024

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Retraction notice to "Increased levels of Th17 cells are associated with non-neuronal acetylcholine in COPD patients" [Immunobiology 219(5) (2014) 392-401].
Mirella Profita, Giusy Daniela Albano, Loredana Riccobono, Caterina Di Sano, Angela Marina Montalbano, Michael Paul Pieper

Immunobiology· September 2024

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Metabolic Analysis and Renal Protective Effects of Linagliptin and Empagliflozin in Alport Syndrome.
Mengyuan Ge, Judith Molina, Ian Tamayo, Guanshi Zhang, Jin-Ju Kim, Michael Paul Pieper

Kidney360· July 2024

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Retraction notice to "In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD" [Immunobiology 217/3 (2012) 345-353].
Mirella Profita, Loredana Riccobono, Angela Marina Montalbano, Anna Bonanno, Maria Ferraro, Michael Paul Pieper

Immunobiology· May 2024

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SGLT2 inhibition promotes glomerular repopulation by cells of renin lineage in experimental kidney disease.
Loïs A K van der Pluijm, Angela Koudijs, Wendy Stam, Joris J T H Roelofs, A H Jan Danser, Michael P Pieper

Acta Physiol (Oxf)· March 2024

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COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway.
Ali Mroueh, Walaa Fakih, Adrien Carmona, Antonin Trimaille, Kensuke Matsushita, Michael Paul Pieper

J Thromb Haemost· January 2024

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Cardioprotective Effect of Empagliflozin and Circulating Ketone Bodies During Acute Myocardial Infarction.
Carlos G Santos-Gallego, Juan Antonio Requena-Ibáñez, Belen Picatoste, Brian Fardman, Kiyotake Ishikawa, Michael Pieper

Circ Cardiovasc Imaging· April 2023

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The SGLT2 inhibitor empagliflozin improves cardiac energy status via mitochondrial ATP production in diabetic mice.
Jungmi Choi, Naoki Matoba, Daiki Setoyama, Daiki Watanabe, Yuichiro Ohnishi, Michael Paul Pieper

Commun Biol· March 2023

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The membrane-associated protein 17 (MAP17) is up-regulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy.
Ander Vergara, Carmen Llorens-Cebrià, Nerea Martos, Irene Martínez-Díaz, Frank Stein, Michael Paul Pieper

Clin Sci (Lond)· January 2023

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Enhanced Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice.
Ander Vergara, Conxita Jacobs-Cacha, Carmen Llorens-Cebria, Alberto Ortiz, Irene Martinez-Diaz, Michael Paul Pieper

Int J Mol Sci· October 2022

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Olodaterol exerts anti-inflammatory effects on COPD airway epithelial cells.
Nan Yang, Gurpreet K Singhera, Yi Xuan Yan, Michael P Pieper, Janice M Leung

Respir Res· February 2021

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SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans.
Heeyoung Chae, Robert Augustin, Eva Gatineau, Eric Mayoux, Mohammed Bensellam, Michael Pieper

Mol Metab· December 2020

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Muscarinic receptor M3 contributes to vascular and neural growth factor up-regulation in severe asthma.
Anna Folino, Vitina Carriero, Michela Bullone, Francesca Bertolini, Antonino Di Stefano, Michael Pieper

Allergy· March 2020

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Second M muscarinic receptor binding site contributes to bronchoprotection by tiotropium.
Loes E M Kistemaker, Carolina R S Elzinga, Christofer S Tautermann, Michael P Pieper, Daniel Seeliger

Br J Pharmacol· August 2019

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Cigarette smoke and non-neuronal cholinergic system in the airway epithelium of COPD patients.
Angela M Montalbano, Caterina Di Sano, Giuseppina Chiappara, Loredana Riccobono, Anna Bonanno, Michael P Pieper

J Cell Physiol· August 2018

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Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction.
Dimitrios Toumpanakis, Konstantinos Loverdos, Vassiliki Tzouda, Vyronia Vassilakopoulou, Eleni Litsiou, Michael Pieper

Int J Chron Obstruct Pulmon Dis· May 2018

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Modelling the asthma phenotype: impact of cigarette smoke exposure.
Maria G Belvisi, Katie Baker, Nicole Malloy, Kristof Raemdonck, Bilel Dekkak, Michael Pieper

Respir Res· May 2018

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Effects of tiotropium bromide on airway hyperresponsiveness and inflammation in mice exposed to organic dust.
Joshua A Gregory, Cecilia Kemi, Jie Ji, Jakob Karén, Ingrid Delin, Michael P Pieper

Pulm Pharmacol Ther· February 2018

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The effect of tiotropium in combination with olodaterol on house dust mite-induced allergic airway disease.
Gerrit John-Schuster, Stan de Kleijn, Yolanda van Wijck, Veerle Kremer, Hermelijn H Smits, Michael P Pieper

Pulm Pharmacol Ther· August 2017

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Autocrine Acetylcholine, Induced by IL-17A via NFκB and ERK1/2 Pathway Activation, Promotes MUC5AC and IL-8 Synthesis in Bronchial Epithelial Cells.
Angela Marina Montalbano, Giusy Daniela Albano, Anna Bonanno, Loredana Riccobono, Caterina Di Sano, Michael Paul Pieper

Mediators Inflamm· May 2017

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Effect of tiotropium on COPD exacerbations: A systematic review.
David M G Halpin, Claus Vogelmeier, Michael P Pieper, Norbert Metzdorf, Frank Richard

Respir Med· May 2016

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