Publications by authors named "Michael R Digruccio"

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Role of complexin 2 in the regulation of hormone secretion from the islet of Langerhans.
Xue Wen Ng, Chen Kong, Michael R DiGruccio, Jeongmin Lee, David W Piston

Am J Physiol Endocrinol Metab· December 2025

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Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans.
Xue Wen Ng, Michael R DiGruccio, Chen Kong, Jeongmin Lee, David W Piston

bioRxiv· October 2024

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Primary cilia control glucose homeostasis via islet paracrine interactions.
Jing W Hughes, Jung Hoon Cho, Hannah E Conway, Michael R DiGruccio, Xue Wen Ng

Proc Natl Acad Sci U S A· April 2020

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The Role of Free Oxygen Radicals in Lasting Hyperexcitability of Rat Subicular Neurons After Exposure to General Anesthesia During Brain Development.
Srdjan M Joksimovic, Michael R DiGruccio, Annalisa Boscolo, Vesna Jevtovic-Todorovic, Slobodan M Todorovic

Mol Neurobiol· January 2020

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The role of T-type calcium channels in the subiculum: to burst or not to burst?
Srdjan M Joksimovic, Pierce Eggan, Yukitoshi Izumi, Sonja Lj Joksimovic, Vesna Tesic, Michael R DiGruccio

J Physiol· October 2017

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Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
Talitha van der Meulen, Alex M Mawla, Michael R DiGruccio, Michael W Adams, Vera Nies

Cell Metab· April 2017

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Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.
Michael R DiGruccio, Alex M Mawla, Cynthia J Donaldson, Glyn M Noguchi, Joan Vaughan

Mol Metab· July 2016

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General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus.
Lorenza Dalla Massara, Hari Prasad Osuru, Azra Oklopcic, Desanka Milanovic, Srdjan Milan Joksimovic, Michael Robert DiGruccio

Anesthesiology· June 2016

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Hyperexcitability of rat thalamocortical networks after exposure to general anesthesia during brain development.
Michael R DiGruccio, Srdjan Joksimovic, Pavle M Joksovic, Nadia Lunardi, Reza Salajegheh

J Neurosci· January 2015

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Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone.
Christine Ayoola, Sung Mi Hwang, Sung Jun Hong, Kirstin E Rose, Christopher Boyd, Michael R DiGruccio

Psychopharmacology (Berl)· September 2014

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Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels.
Peihan Orestes, Hari Prasad Osuru, William E McIntire, Megan O Jacus, Reza Salajegheh, Michael R Digruccio

Diabetes· November 2013

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Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane.
Veit-Simon Eckle, Michael R Digruccio, Victor N Uebele, John J Renger, Slobodan M Todorovic

Neuropharmacology· August 2012

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Free radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway.
Peihan Orestes, Damir Bojadzic, Jeonghan Lee, Emily Leach, Reza Salajegheh, Michael R Digruccio

J Physiol· January 2011

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Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled receptors.
Marilyn H Perrin, Christy R R Grace, Michael R Digruccio, Wolfgang H Fischer, Samir K Maji

J Biol Chem· December 2007

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Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand.
Christy Rani R Grace, Marilyn H Perrin, Jozsef Gulyas, Michael R Digruccio, Jeffrey P Cantle

Proc Natl Acad Sci U S A· March 2007

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A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity.
Alon M Chen, Marilyn H Perrin, Michael R Digruccio, Joan M Vaughan, Bhawanjit K Brar

Proc Natl Acad Sci U S A· February 2005

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NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor.
Christy R R Grace, Marilyn H Perrin, Michael R DiGruccio, Charleen L Miller, Jean E Rivier

Proc Natl Acad Sci U S A· August 2004

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A soluble form of the first extracellular domain of mouse type 2beta corticotropin-releasing factor receptor reveals differential ligand specificity.
Marilyn H Perrin, Michael R DiGruccio, Steven C Koerber, Jean E Rivier, Koichi S Kunitake

J Biol Chem· May 2003

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