Publications by authors named "Michael R Wester"

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Identification of novel substrates for human cytochrome P450 2J2.
Caroline A Lee, David Neul, Andrea Clouser-Roche, Deepak Dalvie, Michael R Wester

Drug Metab Dispos· February 2010

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CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profile.
Ping Kang, Mingxiang Liao, Michael R Wester, J Steven Leeder, Robin E Pearce

Drug Metab Dispos· March 2008

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The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution.
Jason K Yano, Michael R Wester, Guillaume A Schoch, Keith J Griffin, C David Stout

J Biol Chem· September 2004

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The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution.
Michael R Wester, Jason K Yano, Guillaume A Schoch, Christine Yang, Keith J Griffin

J Biol Chem· August 2004

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Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site.
Guillaume A Schoch, Jason K Yano, Michael R Wester, Keith J Griffin, C David Stout

J Biol Chem· March 2004

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An open conformation of mammalian cytochrome P450 2B4 at 1.6-A resolution.
Emily E Scott, You Ai He, Michael R Wester, Mark A White, Christopher C Chin

Proc Natl Acad Sci U S A· November 2003

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Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding.
Michael R Wester, Eric F Johnson, Cristina Marques-Soares, Sylvie Dijols, Patrick M Dansette

Biochemistry· August 2003

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Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes.
Cristina Marques-Soares, Sylvie Dijols, Anne-Christine Macherey, Michael R Wester, Eric F Johnson

Biochemistry· June 2003

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Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes.
Michael R Wester, Eric F Johnson, Cristina Marques-Soares, Patrick M Dansette, Daniel Mansuy

Biochemistry· June 2003

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Purification and crystallization of N-terminally truncated forms of microsomal cytochrome P450 2C5.
Michael R Wester, C David Stout, Eric F Johnson

Methods Enzymol· January 2003

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The structure of microsomal cytochrome P450 2C5: a steroid and drug metabolizing enzyme.
Eric F Johnson, Michael R Wester, C David Stout

Endocr Res· November 2002

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