Publications by authors named "Michael Schleimer"

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Experiments for a systematic comparison between stable-isotope-(deuterium) labeling and radio-((14)C) labeling for the elucidation of the in vitro metabolic pattern of pharmaceutical drugs.
Helge Grunwald, Patrick Hargreaves, Klaus Gebhardt, Dominique Klauer, Arnaud Serafyn, Michael Schleimer

J Pharm Biomed Anal· November 2013

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Investigation of the species-dependent in vitro metabolism of BAL30630 by stable isotope labeling and isotope exchange experiments analyzed by capillary liquid chromatography coupled to mass spectrometry.
Mathias Wind, Helge Grunwald, Klaus Gebhardt, Klaus Illig, Jochen Spickermann, Michael Schleimer

J Chromatogr A· May 2009

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Elucidation of the in vitro metabolic profile of stable isotope labeled BAL19403 by accurate mass capillary liquid chromatography/quadrupole time-of-flight mass spectrometry and isotope exchange.
Mathias Wind, Klaus Gebhardt, Helge Grunwald, Jochen Spickermann, Massimiliano Donzelli, Michael Schleimer

Rapid Commun Mass Spectrom· May 2007

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Investigation of low-abundant in vitro metabolites of stable isotope-labelled BAL4815 by accurate mass capillary-LC-ESI-qTof-MS and MS/MS.
Mathias Wind, Jochen Spickermann, Michael Schleimer, Massimiliano Donzelli, Klaus Gebhardt

J Mass Spectrom· July 2006

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Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL4815 after intravenous infusions (50, 100, and 200 milligrams) and oral administrations (100, 200, and 400 milligrams) of its prodrug, BAL8557, in healthy volunteers.
Anne Schmitt-Hoffmann, Brigitte Roos, Markus Heep, Michael Schleimer, Erhard Weidekamm

Antimicrob Agents Chemother· January 2006

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Single-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteers.
Anne Schmitt-Hoffmann, Brigitte Roos, Michael Schleimer, Jill Sauer, Anthony Man

Antimicrob Agents Chemother· July 2004

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Multiple-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteers.
Anne Schmitt-Hoffmann, Lars Nyman, Brigitte Roos, Michael Schleimer, Jill Sauer

Antimicrob Agents Chemother· July 2004

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Performance and reliability of splitless microliter gradient pumps in a metabolic stability study using cytochrome P450/3A4 and capillary liquid chromatography-mass spectrometry.
Fabian Kuhn, Michael Oehme, Michael Schleimer

J Chromatogr A· November 2003

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Preformulation approaches to improve the oral bioavailability of two novel piperidine renin inhibitors in dog.
Beate Bittner, Ruby Chou, Michael Schleimer, Brita Morgenroth, Manfred Zell

Arzneimittelforschung· October 2002

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