Publications by authors named "Michael Seagar"

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The downregulation of Kv channels in Lgi1mice is accompanied by a profound modification of its interactome and a parallel decrease in Kv channels.
Jorge Ramirez-Franco, Kévin Debreux, Marion Sangiardi, Maya Belghazi, Yujin Kim, Michael Seagar

Neurobiol Dis· June 2024

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A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c.
Christian Lévêque, Yves Maulet, Qili Wang, Marion Rame, Léa Rodriguez, Michael Seagar

Cells· February 2023

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Patient-derived antibodies reveal the subcellular distribution and heterogeneous interactome of LGI1.
Jorge Ramirez-Franco, Kévin Debreux, Johanna Extremet, Yves Maulet, Maya Belghazi, Michael Seagar

Brain· November 2022

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Molecular landscape of BoNT/B bound to a membrane-inserted synaptotagmin/ganglioside complex.
Jorge Ramirez-Franco, Fodil Azzaz, Marion Sangiardi, Géraldine Ferracci, Fahamoe Youssouf, Michael Seagar

Cell Mol Life Sci· August 2022

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Gangliosides interact with synaptotagmin to form the high-affinity receptor complex for botulinum neurotoxin B.
Alessandra Flores, Jorge Ramirez-Franco, Richard Desplantes, Kévin Debreux, Géraldine Ferracci, Michael Seagar

Proc Natl Acad Sci U S A· September 2019

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Chromophore-Assisted Light Inactivation of the V-ATPase V0c Subunit Inhibits Neurotransmitter Release Downstream of Synaptic Vesicle Acidification.
Sylvain Rama, Norah Boumedine-Guignon, Marion Sangiardi, Fahamoe Youssouf, Yves Maulet, Michael Seagar

Mol Neurobiol· May 2019

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LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels.
Michael Seagar, Michael Russier, Olivier Caillard, Yves Maulet, Laure Fronzaroli-Molinieres

Proc Natl Acad Sci U S A· July 2017

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Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor.
Richard Desplantes, Christian Lévêque, Benjamin Muller, Manuela Lotierzo, Géraldine Ferracci, Michael Seagar

Sci Rep· April 2017

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An optical biosensor assay for rapid dual detection of Botulinum neurotoxins A and E.
Christian Lévêque, Géraldine Ferracci, Yves Maulet, Christelle Mazuet, Michel R Popoff, Michael Seagar

Sci Rep· December 2015

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A chip-based assay for botulinum neurotoxin A activity in pharmaceutical preparations.
Christian Lévêque, Géraldine Ferracci, Yves Maulet, Chloé Grand-Masson, Michael Seagar

Appl Microbiol Biotechnol· May 2015

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AaTX1, from Androctonus australis scorpion venom: purification, synthesis and characterization in dopaminergic neurons.
Saoussen Mlayah-Bellalouna, Martial Dufour, Kamel Mabrouk, Hafedh Mejdoub, Edmond Carlier, Michael Seagar

Toxicon· December 2014

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Direct biosensor detection of botulinum neurotoxin endopeptidase activity in sera from patients with type A botulism.
Christian Lévêque, Géraldine Ferracci, Yves Maulet, Christelle Mazuet, Michel Popoff, Michael Seagar

Biosens Bioelectron· July 2014

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A substrate sensor chip to assay the enzymatic activity of Botulinum neurotoxin A.
Christian Lévêque, Géraldine Ferracci, Yves Maulet, Chloé Grand-Masson, Marie-Pierre Blanchard, Michael Seagar

Biosens Bioelectron· November 2013

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A role for V-ATPase subunits in synaptic vesicle fusion?
Oussama El Far, Michael Seagar

J Neurochem· May 2011

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A label-free biosensor assay for botulinum neurotoxin B in food and human serum.
Géraldine Ferracci, Séverine Marconi, Christelle Mazuet, Emmanuel Jover, Marie-Pierre Blanchard, Michael Seagar

Anal Biochem· March 2011

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[SNARE, V-ATPase and neurotransmission].
Oussama El Far, Michael Seagar

Med Sci (Paris)· January 2011

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Calcium-dependent regulation of SNARE-mediated membrane fusion by calmodulin.
Jerome Di Giovanni, Cécile Iborra, Yves Maulet, Christian Lévêque, Oussama El Far, Michael Seagar

J Biol Chem· July 2010

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V-ATPase membrane sector associates with synaptobrevin to modulate neurotransmitter release.
Jérôme Di Giovanni, Sami Boudkkazi, Sumiko Mochida, Andrzej Bialowas, Nada Samari, Michael Seagar

Neuron· July 2010

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A fast, single-vesicle fusion assay mimics physiological SNARE requirements.
Erdem Karatekin, Jérôme Di Giovanni, Cécile Iborra, Jeff Coleman, Ben O'Shaughnessy, Michael Seagar

Proc Natl Acad Sci U S A· February 2010

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A protein chip membrane-capture assay for botulinum neurotoxin activity.
Séverine Marconi, Géraldine Ferracci, Maëlys Berthomieu, Shunji Kozaki, Raymond Miquelis, Michael Seagar

Toxicol Appl Pharmacol· December 2008

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Nuclear localization of a novel human syntaxin 1B isoform.
Sandrine Pereira, Annick Massacrier, Patrice Roll, Alain Vérine, Marie-Christine Etienne-Grimaldi, Michael Seagar

Gene· November 2008

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Toxicity and endocytosis of spinocerebellar ataxia type 6 polyglutamine domains: role of myosin IIb.
Béatrice Marquèze-Pouey, Nicole Martin-Moutot, Marie Sakkou-Norton, Christian Lévêque, Yong Ji, Michael Seagar

Traffic· July 2008

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Distinct evolution of calcium channel antibody types in Lambert-Eaton myasthenic syndrome.
Nicole Martin-Moutot, Luc De Haro, Michael Seagar

J Neuroimmunol· June 2008

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Phoneutria nigriventer toxin 1: a novel, state-dependent inhibitor of neuronal sodium channels that interacts with micro conotoxin binding sites.
Nicole Martin-Moutot, Pascal Mansuelle, Gisèle Alcaraz, Raquel Gouvêa Dos Santos, Marta N Cordeiro, Michael Seagar

Mol Pharmacol· June 2006

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MAU-8 is a Phosducin-like Protein required for G protein signaling in C. elegans.
Caroline Lacoste, Véronique Barthaux, Cécile Iborra, Michael Seagar, Madeleine Erard-Garcia

Dev Biol· June 2006

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