Publications by authors named "Michael Stocks"

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Discovery of a Potent Lysine-Specific Histone Demethylase-1 (LSD-1) Inhibitor for Cancer Treatment via Machine Learning, Molecular Modeling, and In Vitro Validation.
Shuya Wang, Lihui Duo, Zhangyi Ma, Zixuan Zhang, Biyu Hu, Michael J Stocks

Chemistry· December 2025

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Design, Synthesis, and Evaluation of Selective Ubiquitin-Specific Protease 11 (USP11) Inhibitors.
Mostafa A Hassan, Lodewijk V Dekker, Michael J Stocks, Ingrid Dreveny

ACS Omega· December 2025

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Correction to "Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema".
Rebecca L Davie, Hannah J Edwards, D Michael Evans, Simon T Hodgson, Michael J Stocks

J Med Chem· November 2025

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The Characterization of a Gonococcal HicAB Toxin-Antitoxin System Capable of Causing Bacteriostatic Growth Arrest.
Salwa S Bagabas, Jorge Trujillo-Mendoza, Michael J Stocks, David P J Turner, Neil J Oldfield

Microorganisms· July 2025

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Drug-like Antagonists of P2Y Receptor Subtypes: An Update.
Mahesh Puthanveedu, Rebecca Knight, Michael J Stocks

J Med Chem· May 2025

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Discovery of Highly Potent BET Inhibitors based on a Tractable Tricyclic Scaffold.
Jaffer M Zaidi, Eleonora Comeo, Andrew Baxter, Alex G S Preston, Weng C Chan, Michael J Stocks

ACS Med Chem Lett· April 2025

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Rapeseed oleosomes facilitate intestinal lymphatic delivery and oral bioavailability of cannabidiol.
Liuhang Ji, Wanshan Feng, Haojie Chen, YenJu Chu, Abigail Wong, Michael J Stocks

Int J Pharm· January 2025

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Delivery of imiquimod to intestinal lymph nodes following oral administration.
Haojie Chen, Liuhang Ji, Abigail Wong, Yenju Chu, Wanshan Feng, Michael J Stocks

Int J Pharm· December 2024

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Theoretical Study on the Biosynthesis of the Mandapamates: Mechanistic Insights Using Density Functional Theory.
Di Wang, Gerald Pattenden, Kam Loon Fow, Michael J Stocks, Jonathan D Hirst

J Org Chem· September 2024

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Design, Synthesis, and Evaluation of a New Chemotype Fluorescent Ligand for the P2Y Receptor.
Rebecca Knight, Laura E Kilpatrick, Stephen J Hill, Michael J Stocks

ACS Med Chem Lett· July 2024

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Discovery of α-Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein.
Matthew Allison, Rebecca L Davie, Adrian J Mogg, Sally L Hampton, Jonas Emsley, Michael J Stocks

ACS Med Chem Lett· April 2024

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CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans.
Carl W White, Simon Platt, Laura E Kilpatrick, Natasha Dale, Rekhati S Abhayawardana, Michael J Stocks

Sci Signal· March 2024

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Design, Synthesis, and Evaluation of New 1-Benzo[]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Infections.
Fadi Soukarieh, Alaa Mashabi, William Richardson, Eduard Vico Oton, Manuel Romero, Michael J Stocks

J Med Chem· January 2024

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Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3).
Sebastian Dekkers, Dehan Comez, Noemi Karsai, Marta Arimont-Segura, Meritxell Canals, Michael J Stocks

ACS Med Chem Lett· January 2024

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Distribution of lamivudine into lymph node HIV reservoir.
Abigail Wong, Yenju Chu, Haojie Chen, Wanshan Feng, Liuhang Ji, Michael J Stocks

Int J Pharm· December 2023

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Development of lipophilic ester prodrugs of dolutegravir for intestinal lymphatic transport.
Yenju Chu, Abigail Wong, Haojie Chen, Liuhang Ji, Chaolong Qin, Michael J Stocks

Eur J Pharm Biopharm· October 2023

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Small-Molecule Fluorescent Ligands for the CXCR4 Chemokine Receptor.
Sebastian Dekkers, Birgit Caspar, Joëlle Goulding, Nicholas D Kindon, Laura E Kilpatrick, Michael J Stocks

J Med Chem· April 2023

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Design of Quorum Sensing Inhibitor-Polymer Conjugates to Penetrate Biofilms.
Fadi Soukarieh, Pratik Gurnani, Manuel Romero, Nigel Halliday, Michael Stocks

ACS Macro Lett· March 2023

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Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema.
Rebecca L Davie, Hannah J Edwards, D Michael Evans, Simon T Hodgson, Michael J Stocks

J Med Chem· October 2022

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Vegetable oils composition affects the intestinal lymphatic transport and systemic bioavailability of co-administered lipophilic drug cannabidiol.
Wanshan Feng, Chaolong Qin, Salah Abdelrazig, Ziyu Bai, Mekha Raji, Michael J Stocks

Int J Pharm· August 2022

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Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs.
Jack Ayre, Joanna M Redmond, Giovanni Vitulli, Laura Tomlinson, Richard Weaver, Michael J Stocks

J Med Chem· July 2022

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Distribution of a highly lipophilic drug cannabidiol into different lymph nodes following oral administration in lipidic vehicle.
Adelaide Jewell, Alice Brookes, Wanshan Feng, Marianne Ashford, Paul Gellert, Michael J Stocks

Eur J Pharm Biopharm· May 2022

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Is oral lipid-based delivery for drug targeting to the brain feasible?
Alice Brookes, Liuhang Ji, Tracey D Bradshaw, Michael Stocks, David Gray

Eur J Pharm Biopharm· March 2022

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Assessing Lymphatic Uptake of Lipids Using Magnetic Resonance Imaging: A Feasibility Study in Healthy Human Volunteers with Potential Application for Tracking Lymph Node Delivery of Drugs and Formulation Excipients.
Adelaide Jewell, Hannah Williams, Caroline L Hoad, Paul R Gellert, Marianne B Ashford, Michael J Stocks

Pharmaceutics· August 2021

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Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle.
Wanshan Feng, Chaolong Qin, Elena Cipolla, Jong Bong Lee, Atheer Zgair, Michael J Stocks

Pharmaceutics· August 2021

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