Publications by authors named "Michael Stumm"

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First-in human, phase 1, dose-escalation pharmacokinetic and pharmacodynamic study of the oral dual PI3K and mTORC1/2 inhibitor PQR309 in patients with advanced solid tumors (SAKK 67/13).
Andreas Wicki, Nicholas Brown, Alexandros Xyrafas, Vincent Bize, Hanne Hawle, Michael Stumm

Eur J Cancer· June 2018

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Validation of a postfixation tissue storage and transport medium to preserve histopathology and molecular pathology analyses (total and phosphoactivated proteins, and FISH).
Michael M Stumm, Maja R Walker, Caroline Stork, Noelle Hanoteau, Urs Wagner

Am J Clin Pathol· March 2012

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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Gideon Bollag, Peter Hirth, James Tsai, Jiazhong Zhang, Prabha N Ibrahim, Michael Stumm

Nature· September 2010

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Anti-Angiogenic/Vascular Effects of the mTOR Inhibitor Everolimus Are Not Detectable by FDG/FLT-PET.
Michael Honer, Thomas Ebenhan, Peter R Allegrini, Simon M Ametamey, Mike Becquet, Michael Stumm

Transl Oncol· August 2010

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Quantified tumor t1 is a generic early-response imaging biomarker for chemotherapy reflecting cell viability.
Paul M J McSheehy, Claudia Weidensteiner, Catherine Cannet, Stephane Ferretti, Didier Laurent, Michael Stumm

Clin Cancer Res· January 2010

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Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer.
José Baselga, Vladimir Semiglazov, Peter van Dam, Alexey Manikhas, Meritxell Bellet, Michael Stumm

J Clin Oncol· June 2009

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Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.
Kristen Pollizzi, Izabela Malinowska-Kolodziej, Michael Stumm, Heidi Lane, David Kwiatkowski

Mol Cancer· June 2009

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Fate of undifferentiated mouse embryonic stem cells within the rat heart: role of myocardial infarction and immune suppression.
Qing He, Pedro T Trindade, Michael Stumm, Jian Li, Prisca Zammaretti

J Cell Mol Med· January 2009

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Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging.
Christian R Schnell, Frédéric Stauffer, Peter R Allegrini, Terence O'Reilly, Paul M J McSheehy, Michael Stumm

Cancer Res· August 2008

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The Ret receptor tyrosine kinase pathway functionally interacts with the ERalpha pathway in breast cancer.
Anne Boulay, Madlaina Breuleux, Christine Stephan, Caroline Fux, Cathrin Brisken, Michael Stumm

Cancer Res· May 2008

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Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.
Josep Tabernero, Federico Rojo, Emiliano Calvo, Howard Burris, Ian Judson, Michael Stumm

J Clin Oncol· April 2008

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Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure.
Stephane Ferretti, Peter R Allegrini, Terence O'Reilly, Christian Schnell, Michael Stumm

Clin Cancer Res· November 2005

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Expression of mRNA for ROS-generating NADPH oxidases in the aging stomach.
Nathalie Salles, Ildiko Szanto, François Herrmann, Berge Armenian, Michael Stumm

Exp Gerontol· April 2005

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Enzymatic digestion of adult human articular cartilage yields a small fraction of the total available cells.
Marcel Jakob, Olivier Démarteau, Dirk Schäfer, Michael Stumm, Michael Heberer

Connect Tissue Res· July 2004

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STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake.
Kristian Pietras, Michael Stumm, Martine Hubert, Elisabeth Buchdunger, Kristofer Rubin

Clin Cancer Res· September 2003

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Beta1 integrins regulate myoblast fusion and sarcomere assembly.
Martin Schwander, Marco Leu, Michael Stumm, Olivier M Dorchies, Urs T Ruegg

Dev Cell· May 2003

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Inhibition of NO biosynthesis, but not elevated blood pressure, reduces angiogenesis in rat models of secondary hypertension.
Fabrice N Kiefer, Heidi Misteli, Nabil Kalak, Karin Tschudin, Jürgen Fingerle, Michael Stumm

Blood Press· December 2002

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Endothelial, but not the inducible, nitric oxide synthase is detectable in normal and portal hypertensive rats.
Michael Martin Stumm, Daniel D'Orazio, Lazar Trajan Sumanovski, Pierre-Yves Martin, Juerg Reichen

Liver· December 2002

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Accurate gene expression measurement in formalin-fixed and paraffin-embedded tumor tissue.
Daniel D'Orazio, Michael Stumm, Cornel Sieber

Am J Pathol· January 2002

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