Publications by authors named "Michael Weekes"

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Virion proteomics of genetically intact HCMV reveals a regulator of envelope glycoprotein composition that protects against humoral immunity.
Kirsten Bentley, Evelina Statkute, Isa Murrell, Ceri A Fielding, Robin Antrobus, Michael P Weekes

Proc Natl Acad Sci U S A· September 2025

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Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11.
Benjamin J Ravenhill, Marisa Oliveira, George Wood, Ying Di, Joanne Kite, Michael P Weekes

Cell Rep· February 2025

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ISG15-Dependent Stabilisation of USP18 Is Necessary but Not Sufficient to Regulate Type I Interferon Signalling in Humans.
Andri Vasou, Katie Nightingale, Vladimíra Cetkovská, Jonathan Scheler, Connor G G Bamford, Michael P Weekes

Eur J Immunol· February 2025

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Scoping Review of the Published Guidelines for the Management of Traumatic Brachial Plexus Injuries.
Michael A Weekes, Christopher McGhee, Caroline Miller, Abdus Burahee, Ian Rouse

Cureus· February 2025

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Epstein-Barr virus BALF0/1 subverts the Caveolin and ERAD pathways to target B cell receptor complexes for degradation.
Stephanie Pei Tung Yiu, Yifei Liao, Jinjie Yan, Michael P Weekes, Benjamin E Gewurz

Proc Natl Acad Sci U S A· January 2025

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Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly.
Hanqi Li, Alice Fletcher-Etherington, Leah M Hunter, Swati Keshri, Ceri A Fielding, Michael P Weekes

Cell Host Microbe· April 2024

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HCMV US2 co-opts TRC8 to degrade the endoplasmic reticulum-resident protein LMAN2L.
Leah M Hunter, Joanne Kite, Alice Fletcher-Etherington, Katie Nightingale, Luis Nobre, Michael P Weekes

J Gen Virol· April 2024

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HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation.
Virginia-Maria Vlachava, Sepehr Seirafian, Ceri A Fielding, Simon Kollnberger, Rebecca J Aicheler, Michael P Weekes

Proc Natl Acad Sci U S A· December 2023

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Inhibition of human cytomegalovirus replication by interferon alpha can involve multiple anti-viral factors.
Shabab Chowdhury, Katie A Latham, Andy C Tran, Christopher J Carroll, Richard J Stanton, Michael P Weekes

J Gen Virol· December 2023

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Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Jonas D Albarnaz, Joanne Kite, Marisa Oliveira, Hanqi Li, Ying Di, Michael P Weekes

Nat Commun· December 2023

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ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.
Anzelika Rubina, Mihil Patel, Katie Nightingale, Martin Potts, Ceri A Fielding, Michael P Weekes

Proc Natl Acad Sci U S A· August 2023

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An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.
Stephanie Pei Tung Yiu, Cassie Zerbe, David Vanderwall, Edward L Huttlin, Michael P Weekes

Mol Cell· July 2023

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Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity.
Martin Potts, Alice Fletcher-Etherington, Katie Nightingale, Federica Mescia, Laura Bergamaschi, Michael P Weekes

Cell Rep· June 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Michael Weekes

mSphere· April 2023

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Strain-Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins.
Maria Jose Lista, Adam A Witney, Jenna Nichols, Andrew J Davison, Harry Wilson, Michael P Weekes

J Virol· March 2023

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Proteomic analysis of antiviral innate immunity.
Jonas D Albarnaz, Michael P Weekes

Curr Opin Virol· February 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Michael Weekes

J Virol· February 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Michael Weekes

mBio· February 2023

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Large-scale proteomic analysis of muscle-stage ESPs identifies a novel upstream motif for prediction of secreted products.
Bradley Nash, William F Gregory, Rhiannon R White, Anna V Protasio, Steve P Gygi, Michael P Weekes

Front Parasitol· January 2023

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A prospective study of risk factors associated with seroprevalence of SARS-CoV-2 antibodies in healthcare workers at a large UK teaching hospital.
Daniel J Cooper, Sara Lear, Laura Watson, Ashley Shaw, Mark Ferris, Michael P Weekes

J Infect· November 2022

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Demographic, behavioural and occupational risk factors associated with SARS-CoV-2 infection in UK healthcare workers: a retrospective observational study.
Daniel James Cooper, Sara Lear, Nyarie Sithole, Ashley Shaw, Hannah Stark, Michael P Weekes

BMJ Open· November 2022

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Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies.
Delphine M Depierreux, Arwen F Altenburg, Lior Soday, Alice Fletcher-Etherington, Robin Antrobus, Michael P Weekes

PLoS Pathog· June 2022

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Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19.
Jun Wang, Prasanti Kotagiri, Paul A Lyons, Rafia S Al-Lamki, Federica Mescia, Michael P Weekes

iScience· March 2022

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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments.
Stephanie Pei Tung Yiu, Rui Guo, Cassie Zerbe, Michael P Weekes, Benjamin E Gewurz

Cell Rep· March 2022

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Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission.
Dinesh Aggarwal, Ben Warne, Aminu S Jahun, William L Hamilton, Thomas Fieldman, Michael P Weekes

Nat Commun· February 2022

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