Publications by authors named "Michael Wormstone"

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A single-cell transcriptomic atlas of human lens epithelium: identification and functional insights into lens stem/progenitor cells.
Yuzhou Gu, Lu Chen, Shuying Chen, Yuhao Wu, Shengjie Hao, I Michael Wormstone

Stem Cell Res Ther· July 2025

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Lens capsule advanced glycation end products induce senescence in epithelial cells: Implications for secondary cataracts.
Grace Cooksley, Mi-Hyun Nam, Rooban B Nahomi, Johanna Rankenberg, Andrew J O Smith, Yvette M Wormstone, I Michael Wormstone

Aging Cell· October 2024

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Stereolithographic Rapid Prototyping of Clear, Foldable, Non-Refractive Intraocular Lens Designs: A Proof-of-Concept Study.
Veronica Hidalgo-Alvarez, Noelia D Falcon, Julie Eldred, Michael Wormstone, Aram Saeed

Curr Eye Res· August 2024

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27 Advancing the basic understanding and management of posterior capsule opacification following cataract surgery using human donor eyes.
Michael Wormstone

BMJ Open Ophthalmol· November 2022

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GSH Levels Serve As a Biological Redox Switch Regulating Sulforaphane-Induced Cell Fate in Human Lens Cells.
Thao Phuong Ngoc Huynh, Richard P Bowater, Federico Bernuzzi, Shikha Saha, I Michael Wormstone

Invest Ophthalmol Vis Sci· December 2021

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Fluorofenidone inhibits the epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification.
Michael Wormstone

Arq Bras Oftalmol· June 2021

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Interactions between polyphenolic antioxidants quercetin and naringenin dictate the distinctive redox-related chemical and biological behaviour of their mixtures.
Monika Baranowska, Zuzanna Koziara, Klaudia Suliborska, Wojciech Chrzanowski, Michael Wormstone

Sci Rep· June 2021

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Assessment of intraocular lens/capsular bag biomechanical interactions following cataract surgery in a human in vitro graded culture capsular bag model.
I Michael Wormstone, Niklas B Damm, Martin Kelp, Julie A Eldred

Exp Eye Res· April 2021

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Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Jingru Huangfu, Caili Hao, Zongbo Wei, I Michael Wormstone, Hong Yan

Cell Death Dis· April 2021

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The human capsular bag model of posterior capsule opacification.
I Michael Wormstone

Eye (Lond)· February 2020

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Aspirin inhibits TGFβ2-induced epithelial to mesenchymal transition of lens epithelial cells: selective acetylation of K56 and K122 in histone H3.
Mi-Hyun Nam, Andrew J O Smith, Mina B Pantcheva, Ko Uoon Park, Joseph A Brzezinski, I Michael Wormstone

Biochem J· January 2020

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Development and Validation of a Deep Learning System to Detect Glaucomatous Optic Neuropathy Using Fundus Photographs.
Hanruo Liu, Liu Li, I Michael Wormstone, Chunyan Qiao, Chun Zhang

JAMA Ophthalmol· December 2019

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Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention.
Andrew J O Smith, Julie A Eldred, I Michael Wormstone

Invest Ophthalmol Vis Sci· September 2019

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An In Vitro Human Lens Capsular Bag Model Adopting a Graded Culture Regime to Assess Putative Impact of IOLs on PCO Formation.
Julie A Eldred, Jiyun Zheng, Sulin Chen, I Michael Wormstone

Invest Ophthalmol Vis Sci· January 2019

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Mutation profiles of congenital cataract genes in 21 northern Chinese families.
Xiao Hui Zhang, Jin Da Wang, Hong Yan Jia, Jing Shang Zhang, Yang Li, Michael Wormstone

Mol Vis· November 2018

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Sulforaphane promotes ER stress, autophagy, and cell death: implications for cataract surgery.
Hanruo Liu, Andrew Jo Smith, Simon Sr Ball, Yongping Bao, Richard P Bowater, I Michael Wormstone

J Mol Med (Berl)· May 2017

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PARP-1 inhibition influences the oxidative stress response of the human lens.
Andrew J O Smith, Simon S R Ball, Richard P Bowater, I Michael Wormstone

Redox Biol· August 2016

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Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target.
Julie A Eldred, Matthew McDonald, Helen S Wilkes, David J Spalton, I Michael Wormstone

Sci Rep· April 2016

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Improving the drug development process by reducing the impact of adverse events: the case of cataracts considered.
Andrew F Smith, Alexander Klotz, I Michael Wormstone

Drug Discov Today· March 2016

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An in vitro evaluation of the Anew Zephyr open-bag IOL in the prevention of posterior capsule opacification using a human capsular bag model.
Julie A Eldred, David J Spalton, I Michael Wormstone

Invest Ophthalmol Vis Sci· September 2014

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Effect of total lens epithelial cell destruction on intraocular lens fixation in the human capsular bag.
David J Spalton, Sarah L Russell, Richard Evans-Gowing, Julie A Eldred, I Michael Wormstone

J Cataract Refract Surg· February 2014

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Serum deprivation can suppress receptor-mediated calcium signaling in pterygial-derived fibroblasts.
Chunlai Fang, Christopher D Illingworth, Limin Qian, I Michael Wormstone

Invest Ophthalmol Vis Sci· July 2013

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Sigma 1 receptor stimulation protects against oxidative damage through suppression of the ER stress responses in the human lens.
Lixin Wang, Julie A Eldred, Peter Sidaway, Julie Sanderson, Andrew J O Smith, I Michael Wormstone

Mech Ageing Dev· May 2013

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MMP2 activity is critical for TGFβ2-induced matrix contraction--implications for fibrosis.
Julie A Eldred, Lisa M Hodgkinson, Lucy J Dawes, John R Reddan, Dylan R Edwards, I Michael Wormstone

Invest Ophthalmol Vis Sci· June 2012

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A fully human in vitro capsular bag model to permit intraocular lens evaluation.
Lucy J Dawes, Christopher D Illingworth, I Michael Wormstone

Invest Ophthalmol Vis Sci· January 2012

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