Publications by authors named "Michal Smida"

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Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode.
Paula Martín Moyano, Tadeáš Kubina, Štěpán Owen Paruch, Aneta Jarošková, Jan Novotný

Angew Chem Int Ed Engl· January 2025

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A novel thrombocytopenia-4-causing CYCS gene variant decreases caspase activity: Three-generation study.
Jiří Štika, Michaela Pešová, Kateřina Staňo Kozubík, Magdalena Skalníková, Lenka Dostálová

Br J Haematol· December 2024

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CD20 expression regulates CD37 levels in B-cell lymphoma - implications for immunotherapies.
Malgorzata Bobrowicz, Aleksandra Kusowska, Marta Krawczyk, Andriy Zhylko, Christopher Forcados

Oncoimmunology· June 2024

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Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells.
Zankruti Dave, Olga Vondálová Blanářová, Štěpán Čada, Pavlína Janovská, Nikodém Zezula

Front Cell Dev Biol· February 2022

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A Variant in a Czech Family with Monoallelic Bernard-Soulier Syndrome.
Magdalena Skalníková, Kateřina Staňo Kozubík, Jakub Trizuljak, Zuzana Vrzalová, Lenka Radová

Int J Mol Sci· January 2022

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Functional analysis of germline mutation causing inherited thrombocytopenia and secondary acute lymphoblastic leukemia or essential thrombocythemia.
Katerina Stano Kozubik, Lenka Radova, Kamila Reblova, Michal Smida, Marketa Zaliova Kubricanova

Platelets· August 2021

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Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro.
Aneta Ledererova, Lenka Dostalova, Veronika Kozlova, Helena Peschelova, Adriana Ladungova, Michal Smida

J Immunother Cancer· August 2021

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Current State of CAR T-Cell Therapy in Chronic Lymphocytic Leukemia.
Veronika Mancikova, Michal Smida

Int J Mol Sci· May 2021

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CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells.
Veronika Kozlova, Aneta Ledererova, Adriana Ladungova, Helena Peschelova, Pavlina Janovska, Michal Smida

PLoS One· June 2020

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Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia.
Veronika Mancikova, Helena Peschelova, Veronika Kozlova, Aneta Ledererova, Adriana Ladungova, Michal Smida

J Immunother Cancer· March 2020

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MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated.
Michal Smida, Ferran Fece de la Cruz, Claudia Kerzendorfer, Iris Z Uras, Barbara Mair

Nat Commun· December 2016

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Treatment of chronic lymphocytic leukemia with monoclonal antibodies, where are we heading?
Michael Doubek, Michal Šmída

Expert Rev Hematol· December 2015

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A reversible gene trap collection empowers haploid genetics in human cells.
Tilmann Bürckstümmer, Carina Banning, Philipp Hainzl, Richard Schobesberger, Claudia Kerzendorfer, Michal Smida

Nat Methods· October 2013

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PAG/Cbp suppression reveals a contribution of CTLA-4 to setting the activation threshold in T cells.
Michal Smida, Clemens Cammann, Slavyana Gurbiel, Nadja Kerstin, Holger Lingel

Cell Commun Signal· April 2013

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Functional drug-gene interactions in lung cancer.
Michal Smida, Sebastian M B Nijman

Expert Rev Mol Diagn· April 2012

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A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.
Markus K Muellner, Iris Z Uras, Bianca V Gapp, Claudia Kerzendorfer, Michal Smida

Nat Chem Biol· September 2011

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Integrating signals from the T-cell receptor and the interleukin-2 receptor.
Tilo Beyer, Mandy Busse, Kroum Hristov, Slavyana Gurbiel, Michal Smida

PLoS Comput Biol· August 2011

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Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling.
Christine Börner, Michal Smida, Volker Höllt, Burkhart Schraven, Jürgen Kraus

J Biol Chem· December 2009

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Mechanisms of opioid-mediated inhibition of human T cell receptor signaling.
Christine Börner, Beate Warnick, Michal Smida, Roland Hartig, Jonathan A Lindquist

J Immunol· July 2009

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Control of lymphocyte development and activation by negative regulatory transmembrane adapter proteins.
Luca Simeoni, Jonathan A Lindquist, Michal Smida, Vanessa Witte, Boerge Arndt

Immunol Rev· August 2008

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A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration.
Anita Posevitz-Fejfár, Michal Smída, Stefanie Kliche, Roland Hartig, Burkhart Schraven

Eur J Immunol· January 2008

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Fyn regulates the duration of TCR engagement needed for commitment to effector function.
Andrew Filby, Benedict Seddon, Joanna Kleczkowska, Robert Salmond, Peter Tomlinson, Michal Smida

J Immunol· October 2007

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A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation.
Michal Smida, Anita Posevitz-Fejfar, Vaclav Horejsi, Burkhart Schraven, Jonathan A Lindquist

Blood· July 2007

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Right time, right place: the organization of membrane proximal signaling.
Luca Simeoni, Michal Smida, Vilmos Posevitz, Burkhart Schraven, Jonathan A Lindquist

Semin Immunol· February 2005

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