Publications by authors named "Michala Prause"

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The Gut Microbial Metabolite Butyrate Alleviates IL-1β-Induced Mitochondrial Dysfunction and Oxidative Stress in Pancreatic Islets.
Signe Schultz Pedersen, Richard Denis Maxime De Mets, Joana Mendes Lopes de Melo, Andrea Irazoki, Patrick E MacDonald, Michala Prause

FASEB J· June 2025

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Protection of beta cells against cytokine-induced apoptosis by the gut microbial metabolite butyrate.
Kasper Suhr Jørgensen, Signe Schultz Pedersen, Siv Annegrethe Hjorth, Nils Billestrup, Michala Prause

FEBS J· January 2025

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Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction.
Signe Schultz Pedersen, Lars Roed Ingerslev, Mathias Olsen, Michala Prause, Nils Billestrup

FEBS J· February 2024

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Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.
Adriana Ibarra Urizar, Michala Prause, Lars Roed Ingerslev, Matthew Wortham, Yinghui Sui

Cell Death Dis· July 2023

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Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice.
Signe Schultz Pedersen, Michala Prause, Christina Sørensen, Joachim Størling, Thomas Moritz

Int J Mol Sci· February 2023

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Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells.
Signe Schultz Pedersen, Michala Prause, Kristine Williams, Romain Barrès, Nils Billestrup

J Biol Chem· September 2022

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Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction.
Michala Prause, Signe Schultz Pedersen, Violeta Tsonkova, Min Qiao, Nils Billestrup

Int J Mol Sci· September 2021

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, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients.
Tina Fløyel, Kira Meyerovich, Michala C Prause, Simranjeet Kaur, Caroline Frørup

Diabetes· February 2021

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Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.
Adriana Ibarra Urizar, Michala Prause, Matthew Wortham, Yinghui Sui, Peter Thams

Mol Cell Endocrinol· October 2019

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Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis.
Seyed Mojtaba Ghiasi, Mattias Salling Dahllöf, Yama Osmai, Mirwais Osmai, Kathrine Kronberg Jakobsen, Michala Cecilie Burstein Prause

Mol Cell Endocrinol· December 2018

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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression.
Michala Prause, Christopher Michael Mayer, Caroline Brorsson, Klaus Stensgaard Frederiksen, Nils Billestrup

J Diabetes Res· December 2016

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TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells.
Michala Prause, Lukas Adrian Berchtold, Adriana Ibarra Urizar, Mette Hyldgaard Trauelsen, Nils Billestrup

Mol Cell Endocrinol· January 2016

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JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis.
Michala Prause, Dan Ploug Christensen, Nils Billestrup, Thomas Mandrup-Poulsen

PLoS One· February 2015

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Apolipoprotein CIII reduces proinflammatory cytokine-induced apoptosis in rat pancreatic islets via the Akt prosurvival pathway.
Joachim Størling, Lisa Juntti-Berggren, Gunilla Olivecrona, Michala C Prause, Per-Olof Berggren

Endocrinology· August 2011

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Subretinal posterior pole injury induces selective proliferation of RPE cells in the periphery in in vivo studies in pigs.
Jens F Kiilgaard, Jan U Prause, Michala Prause, Erik Scherfig, Mogens H Nissen

Invest Ophthalmol Vis Sci· January 2007

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