Publications by authors named "Michele Simbolo"

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PI3K/mTORC2-RICTOR axis in early squamous non-small-cell lung cancer: genomics, molecular expression, and clinical relevance.
Sara Pilotto, Lorenzo Belluomini, Federico Monaca, Michele Simbolo, Antonio Agostini

Ther Adv Med Oncol· November 2025

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White paper on best practices for translational research in neuroendocrine neoplasms.
Jerome Cros, Oriol Casanovas, Justo P Castaño, Talya Dayton, Alejandro Garcia Alvarez, Michele Simbolo

J Neuroendocrinol· October 2025

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Prognostic and predictive implications of tumor suppressor gene alterations in non-small cell lung cancer.
Marco Sposito, Lorenzo Belluomini, Riccardo Nocini, Jessica Insolda, Ilaria Mariangela Scaglione, Michele Simbolo

Sci Rep· October 2025

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Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization.
Antonio Pea, Michele Bevere, Anastasios Gkountakos, Davide Pasini, Denise Fiorini, Michele Simbolo

J Pathol· August 2025

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ARID1A mutational status in non-small cell lung cancer: from molecular pathology to clinical implications with a focus on the relationships with EGFR.
Claudia Di Lecce, Serena Eccher, Michele Simbolo, Alessandra Cocomazzi, Maria L Piredda

Lung Cancer· July 2025

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Oncocytic and spindle cell typical carcinoids of lung: different immunophenotype and biological behavior.
Giovanna Sabella, Giovanni Centonze, Patrick Maisonneuve, Federica Grillo, Vincenzo Lagano, Michele Simbolo

J Pathol Clin Res· March 2025

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Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres).
Paola Mattiolo, Michele Bevere, Andrea Mafficini, Anna Vera D Verschuur, Martina Calicchia, Michele Simbolo

Endocr Pathol· December 2024

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Tubulocystic Carcinoma of Bile Ducts: A Distinct Type of Cholangiocarcinoma Associated With Adenofibroma-type Lesions.
Francesca Masetto, Andrea Mafficini, Burcu Saka, Ayse Armutlu, Deyali Chatterjee, Michele Simbolo

Am J Surg Pathol· September 2024

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Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms.
Valentina Angerilli, Giovanna Sabella, Michele Simbolo, Vincenzo Lagano, Giovanni Centonze

Br J Cancer· July 2024

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Tissue- and liquid-biopsy based NGS profiling in advanced non-small-cell lung cancer in a real-world setting: the IMMINENT study.
Marco Sposito, Lorenzo Belluomini, Riccardo Nocini, Jessica Insolda, Ilaria Mariangela Scaglione, Michele Simbolo

Front Oncol· July 2024

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Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives.
Michele Simbolo, Giovanni Centonze, Anastasios Gkountakos, Valentina Monti, Patrick Maisonneuve

Virchows Arch· May 2024

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Exceptional Response in BRAF p.V600E-Mutant Enteric-Type Adenocarcinoma of the Lung With Cutaneous Spread: A Case Report.
Marco Sposito, Ilaria Mariangela Scaglione, Serena Eccher, Luca Pasqualin, Alice Avancini, Michele Simbolo

JTO Clin Res Rep· December 2023

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Editorial: Primary and acquired resistance in lung cancer.
Rossella Bruno, Michele Simbolo, Iacopo Petrini

Front Oncol· November 2023

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Clinical and Genomic Characterization of Pancreatic Ductal Adenocarcinoma with Signet-Ring/Poorly Cohesive Cells.
Michele Simbolo, Nicola Silvestris, Giuseppe Malleo, Andrea Mafficini, Laura Maggino

Mod Pathol· September 2023

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Transcriptome analysis of primary sporadic neuroendocrine tumours of the intestine identified three different molecular subgroups.
Paola Mattiolo, Anastasios Gkountakos, Giovanni Centonze, Michele Bevere, Paola Piccoli, Michele Simbolo

Pathol Res Pract· August 2023

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An Overview of Circulating Biomarkers in Neuroendocrine Neoplasms: A Clinical Guide.
Michele Bevere, Francesca Masetto, Maria Elena Carazzolo, Alice Bettega, Anastasios Gkountakos, Michele Simbolo

Diagnostics (Basel)· August 2023

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Atypical meningiomas with an immunohistochemical profile consistent with hypermetabolic or proliferative molecular groups show high mitotic index, chromosomal instability, and higher recurrence risk.
Valeria Barresi, Serena Ammendola, Michele Simbolo, Serena Pedron, Maria Caffo

Virchows Arch· July 2023

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Ascl1 and OTP tumour expressions are associated with disease-free survival in lung atypical carcinoids.
Giovanni Centonze, Patrick Maisonneuve, Michele Simbolo, Vincenzo Lagano, Federica Grillo

Histopathology· May 2023

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Long-term organoid culture of a small intestinal neuroendocrine tumor.
Sabrina D'Agosto, Elena Fiorini, Francesco Pezzini, Pietro Delfino, Michele Simbolo

Front Endocrinol (Lausanne)· April 2023

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Loss of Primary Cilia Potentiates Pathway Activation in Rhabdoid Colorectal Carcinoma: A Series of 21 Cases Showing Ciliary Rootlet CoiledCoil () Alterations.
Andrea Remo, Federica Grillo, Luca Mastracci, Michele Simbolo, Matteo Fassan

Genes (Basel)· April 2023

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Extrahepatic Distal Cholangiocarcinoma vs. Pancreatic Ductal Adenocarcinoma: Histology and Molecular Profiling for Differential Diagnosis and Treatment.
Anastasios Gkountakos, Filippo M Martelli, Nicola Silvestris, Michele Bevere, Mario De Bellis, Michele Simbolo

Cancers (Basel)· February 2023

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Lung carcinoid tumours: histology and Ki-67, the eternal rivalry.
Giovanni Centonze, Patrick Maisonneuve, Michele Simbolo, Vincenzo Lagano, Federica Grillo

Histopathology· January 2023

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An Insight on Functioning Pancreatic Neuroendocrine Neoplasms.
Michele Bevere, Anastasios Gkountakos, Filippo Maria Martelli, Aldo Scarpa, Claudio Luchini, Michele Simbolo

Biomedicines· January 2023

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Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma.
Andrea Mafficini, Michele Simbolo, Tatsuhiro Shibata, Seung-Mo Hong, Antonio Pea

Mod Pathol· December 2022

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Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications.
Michele Simbolo, Giovanni Centonze, Luca Giudice, Federica Grillo, Patrick Maisonneuve

Cancers (Basel)· September 2022

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