Publications by authors named "Michelle Detry"

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Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial.
Lennie Derde, Anthony C Gordon, Paul R Mouncey, Farah Al-Beidh, Kathryn M Rowan, Michelle A Detry

Thorax· July 2025

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Strategies to Promote Resiliency: A Randomized Embedded Multifactorial Adaptative Platform (REMAP) Clinical Trial to Study Interventions to Improve Recovery After Surgery in High-Risk Patients.
Katherine M Reitz, Hasan Nassereldine, Jason Kennedy, Ryan Zeh, Farah Khandwala, Michelle Detry

Ann Surg Open· June 2025

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Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial.

JAMA Neurol· April 2025

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Intranasal oxytocin for apathy in people with frontotemporal dementia (FOXY): a multicentre, randomised, double-blind, placebo-controlled, adaptive, crossover, phase 2a/2b superiority trial.
Kristy K L Coleman, Scott Berry, Jeffrey Cummings, Ging-Yuek R Hsiung, Robert Laforce, Michelle A Detry

Lancet Neurol· February 2025

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Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Sabrina Paganoni, Christina N Fournier, Eric A Macklin, Lori B Chibnik, Melanie Quintana, Michelle A Detry

JAMA Netw Open· February 2025

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Pridopidine in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial.

JAMA· February 2025

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CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial.

JAMA· February 2025

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Favipiravir for COVID-19 in adults in the community in PRINCIPLE, an open-label, randomised, controlled, adaptive platform trial of short- and longer-term outcomes.
Fd Richard Hobbs, Oghenekome A Gbinigie-Thompson, Milensu Shanyinde, Ly-Mee Yu, Victoria Harris, Michelle A Detry

J Infect· October 2024

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Thrombectomy for Stroke With Large Infarct on Noncontrast CT: The TESLA Randomized Clinical Trial.

JAMA· September 2024

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Ivermectin for COVID-19 in adults in the community (PRINCIPLE): An open, randomised, controlled, adaptive platform trial of short- and longer-term outcomes.
Gail Hayward, Ly-Mee Yu, Paul Little, Oghenekome Gbinigie, Milensu Shanyinde, Michelle A Detry

J Infect· April 2024

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Simvastatin in Critically Ill Patients with Covid-19.

N Engl J Med· December 2023

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Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.

JAMA· November 2023

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Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis.
Melanie Quintana, Benjamin R Saville, Matteo Vestrucci, Michelle A Detry, Lori Chibnik

Ann Neurol· September 2023

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Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.

JAMA· April 2023

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Conditional Power: How Likely Is Trial Success?
Benjamin R Saville, Michelle A Detry, Kert Viele

JAMA· February 2023

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Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.

JAMA· January 2023

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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Christopher C Butler, F D Richard Hobbs, Oghenekome A Gbinigie, Najib M Rahman, Gail Hayward, Michelle A Detry

Lancet· January 2023

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Colchicine for COVID-19 in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial.
Jienchi Dorward, Ly-Mee Yu, Gail Hayward, Benjamin R Saville, Oghenekome Gbinigie, Michelle A Detry

Br J Gen Pract· July 2022

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Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: A Multicenter Randomized Clinical Trial.
Georgene W Hergenroeder, Shoji Yokobori, Huimahn Alex Choi, Karl Schmitt, Michelle A Detry

Neurocrit Care· April 2022

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National Institutes of Health Stroke Scale as an Outcome in Stroke Research: Value of ANCOVA Over Analyzing Change From Baseline.
Eva A Mistry, Sharon D Yeatts, Pooja Khatri, Akshitkumar M Mistry, Michelle Detry

Stroke· April 2022

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Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

JAMA· April 2022

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Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development.
Sabrina Paganoni, James D Berry, Melanie Quintana, Eric Macklin, Benjamin R Saville, Michelle A Detry

Ann Neurol· February 2022

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How to Use and Interpret the Results of a Platform Trial: Users' Guide to the Medical Literature.
Jay J H Park, Michelle A Detry, Srinivas Murthy, Gordon Guyatt, Edward J Mills

JAMA· January 2022

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Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

JAMA· November 2021

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Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.
Ly-Mee Yu, Mona Bafadhel, Jienchi Dorward, Gail Hayward, Benjamin R Saville, Michelle A Detry

Lancet· September 2021

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