Publications by authors named "Michelle DuPont"

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The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.
Mandy Lawson, Natalie Cureton, Susana Ros, Azadeh Cheraghchi-Bashi, Jelena Urosevic, Michelle DuPont

Cancer Res· December 2023

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BET inhibition targets ABC-DLBCL constitutive B-cell receptor signaling through PAX5.
Derek B Oien, Samanta Sharma, Maureen M Hattersley, Michelle DuPont, Steven W Criscione

Blood Adv· September 2023

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A pharmacokinetic-pharmacodynamic model for the MET tyrosine kinase inhibitor, savolitinib, to explore target inhibition requirements for anti-tumour activity.
Rhys D O Jones, Mike Grondine, Alexandra Borodovsky, Maryann San Martin, Michelle DuPont

Br J Pharmacol· February 2021

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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Kerry A Whalen, Brian H White, James M Quinn, Kristina Kriksciukaite, Rossitza Alargova, Michelle M DuPont

Mol Cancer Ther· November 2019

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Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
Brian H White, Kerry Whalen, Kristina Kriksciukaite, Rossitza Alargova, Tsun Au Yeung, Michelle DuPont

J Med Chem· March 2019

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Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.
Emily A Peterson, Alessandro A Boezio, Paul S Andrews, Christiane M Boezio, Tammy L Bush, Michelle DuPont

Bioorg Med Chem Lett· August 2012

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Discovery of triazine-benzimidazoles as selective inhibitors of mTOR.
Emily A Peterson, Paul S Andrews, Xuhai Be, Alessandro A Boezio, Tammy L Bush, Michelle DuPont

Bioorg Med Chem Lett· April 2011

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IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis.
Lisa Schopf, Anneli Savinainen, Karen Anderson, Julie Kujawa, Michelle DuPont

Arthritis Rheum· October 2006

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Mice deficient in PKC theta demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases.
Karen Anderson, Michael Fitzgerald, Michelle Dupont, Tao Wang, Nancy Paz

Autoimmunity· September 2006

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