Publications by authors named "Michelle Ehrlich"

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miR155 triplicated in Down syndrome regulates hippocampal GABAergic neurogenesis in Alzheimer's disease.
Xiaodong Zhu, Jean-Vianney Haure-Mirande, Mesude Bicak, Pengfei Dong, Ilya Kruglikov, Michelle E Ehrlich

bioRxiv· September 2025

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QuadST identifies cell-cell interaction-changed genes in spatially resolved transcriptomics data.
Xiaoyu Song, Yuqing Shang, Michelle E Ehrlich, Panos Roussos, Guo-Cheng Yuan

Genome Res· August 2025

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Cerulenin partially corrects the disrupted developmental transcriptomic signature in Huntington's disease striatal medium spiny neurons.
Carlos Galicia Aguirre, Kizito-Tshitoko Tshilenge, Elena Battistoni, Alejandro Lopez-Ramirez, Swati Naphade, Michelle E Ehrlich

Stem Cells· July 2025

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Characterization of human cytomegalovirus infection dynamics in human microglia.
Marcos Nuevalos Guaita, Tajudeen O Jimoh, Emma B Barrall, Kristina E Atanasoff, Michelle E Ehrlich

J Gen Virol· April 2025

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Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation.
Emilie L Castranio, Merina Varghese, Elentina K Argyrousi, Kuldeep Tripathi, Linda Söderberg, Michelle E Ehrlich

bioRxiv· March 2025

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Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.
Matthew G Engel, Sushma Narayan, Min-Hui Cui, Craig A Branch, Xusheng Zhang, Michelle Ehrlich

J Alzheimers Dis· January 2025

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Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain.
Benjamin P Readhead, Diego F Mastroeni, Qi Wang, Maria A Sierra, Camila de Ávila, Michelle E Ehrlich

Alzheimers Dement· January 2025

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Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.
Allen L Pan, Mickael Audrain, Emmy Sakakibara, Rajeev Joshi, Xiaodong Zhu, Michelle E Ehrlich

Front Aging Neurosci· June 2024

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TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.
Jordi Creus-Muncunill, Jean Vianney Haure-Mirande, Daniele Mattei, Joanna Bons, Angie V Ramirez, Michelle E Ehrlich

J Neuroinflammation· March 2024

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Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing.
Kizito-Tshitoko Tshilenge, Joanna Bons, Carlos Galicia Aguirre, Cristian Geronimo-Olvera, Samah Shah, Michelle E Ehrlich

Neurobiol Dis· January 2024

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Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease.
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich

Biomolecules· January 2024

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QuadST: A Powerful and Robust Approach for Identifying Cell-Cell Interaction-Changed Genes on Spatially Resolved Transcriptomics.
Jinmyung Choi, Michelle E Ehrlich, Panos Roussos, Pei Wang, Guo-Cheng Yuan

bioRxiv· December 2023

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Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy.
Sam Gandy, Michelle E Ehrlich

J Neuroinflammation· November 2023

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Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease.
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Ranjaraju, Nicholas T Seyfried, Michelle E Ehrlich

Res Sq· October 2023

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Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease.
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Ranjaraju, Nicholas T Seyfried, Michelle E Ehrlich

bioRxiv· September 2023

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miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy.
Sam Gandy, Michelle E Ehrlich

J Neuroinflammation· September 2023

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Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.
Georgina Perez Garcia, Mesude Bicak, Jacqueline Buros, Jean-Vianney Haure-Mirande, Gissel M Perez, Michelle E Ehrlich

Front Dement· September 2023

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Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.
Allen L Pan, Mickael Audrain, Emmy Sakakibara, Rajeev Joshi, Xiaodong Zhu, Michelle E Ehrlich

bioRxiv· August 2023

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Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease.
Emilie L Castranio, Philip Hasel, Jean-Vianney Haure-Mirande, Angie V Ramirez Jimenez, B Wade Hamilton, Michelle E Ehrlich

Alzheimers Dement· June 2023

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Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy.
Korey Kam, Kenny Vetter, Rachel A Tejiram, Ward D Pettibone, Kaitlyn Shim, Michelle E Ehrlich

J Neurosci· June 2023

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Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice.
Amelia D Dunn, Shivon A Robinson, Chiso Nwokafor, Molly Estill, Julia Ferrante, Michelle E Ehrlich

Front Behav Neurosci· June 2023

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BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT mouse model of tauopathy.
Georgina Perez-Garcia, Mesude Bicak, Jean-Vianney Haure-Mirande, Gissel M Perez, Alena Otero-Pagan, Michelle E Ehrlich

Neurosci Lett· February 2023

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Moving the Needle on Alzheimer's Disease with an Anti-Oligomer Antibody.
Sam Gandy, Michelle E Ehrlich

N Engl J Med· January 2023

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Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females.
Allen L Pan, Mickael Audrain, Emmy Sakakibara, Rajeev Joshi, Xiaodong Zhu, Michelle E Ehrlich

Cells· December 2022

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A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells.
Juliet Mengaziol, Amelia D Dunn, Gregory Salimando, Lisa Wooldridge, Jordi Crues-Muncunill, Michelle E Ehrlich

PLoS One· December 2022

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